#MerTK - Twitter Hashtag

10 months ago

#EndothelialCell #MerTK #Efferocytosis #Atherosclerosis EC MerTK KO🐭+ AAV8-PCSK9 + #HighFatDiet 2-mo 👉⏫lesion burden 👉⏫NADPH oxidase 👉⏫inflamm cytokines Aortic Arch lesion #Proteomics➡️ ⏫TGFβ HIF1α Wnt3a IL2 ⏬LARP1 NAMPT TEAD1 Zufeng Ding lab #RedoxBiol 2025 https://t.co/y0ntOn2ZzR

HaoYin20's tweet photo. #EndothelialCell #MerTK #Efferocytosis #Atherosclerosis

EC MerTK KO🐭+ AAV8-PCSK9 + #HighFatDiet 2-mo
👉⏫lesion burden
👉⏫NADPH oxidase
👉⏫inflamm cytokines

Aortic Arch lesion #Proteomics➡️
⏫TGFβ HIF1α Wnt3a IL2
⏬LARP1 NAMPT TEAD1

Zufeng Ding lab #RedoxBiol 2025
https://t.co/y0ntOn2ZzR

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MAIDEN @MAIDEN_MAFLD

over 2 years ago

🆕 study in a @ScienceTM discover that a protein called #MERTK plays a key role in fibrosis in various organs including liver, lung and kidney, which holds immense promise in treating #fibrosis — scar tissue that interferes with organ function. #MAFLD

MAIDEN_MAFLD's tweet photo. 🆕 study in a @ScienceTM discover that a protein called #MERTK plays a key role in fibrosis in various organs including liver, lung and kidney, which holds immense promise in treating #fibrosis — scar tissue that interferes with organ function. #MAFLD https://t.co/NuSTOreCAs

MAIDEN @MAIDEN_MAFLD

almost 3 years ago

📌Fibrotic diseases account for nearly half of worldwide deaths. 📌 Fibrosis shares common features among tissues. 📌Could we see one day a drug that treat organ fibrosis? 🤔 #livertwitter #medtwitter #MAFLD

MAIDEN_MAFLD's tweet photo. 📌Fibrotic diseases account for nearly half of worldwide deaths.
📌 Fibrosis shares common features among tissues.
📌Could we see one day a drug that treat organ fibrosis? 🤔
#livertwitter #medtwitter #MAFLD https://t.co/KMslZlqDBi

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MAIDEN @MAIDEN_MAFLD

over 2 years ago

🆕 study in a @ScienceTM discover that a protein called #MERTK plays a key role in fibrosis in various organs including liver, lung and kidney, which holds immense promise in treating #fibrosis — scar tissue that interferes with organ function. #MAFLD

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Australian Science Media Centre @AusSMC

over 2 years ago

🧬Inhibiting a gene called Mer tyrosine kinase #MERTK can reduce fibrosis in multiple organs, including the liver, kidneys and lungs, say @WestmeadInst @Sydney_Uni @GarvanInstitute and @UNSW https://t.co/kjh7JBBAyB

AusSMC's tweet photo. 🧬Inhibiting a gene called Mer tyrosine kinase #MERTK can reduce fibrosis in multiple organs, including the liver, kidneys and lungs, say @WestmeadInst @Sydney_Uni @GarvanInstitute and @UNSW

https://t.co/kjh7JBBAyB https://t.co/T5IexftGhV

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Hao Yin

@HaoYin20

over 2 years ago

My continued biomedical education Specialized Pro-resolving Mediators in vascular inflammation and atherosclerotic cardiovascular disease Lipoxin Resolvin Protectin Maresin #EndothelialCell-#Neutrophil coordination in SPM biosynthesis🤠 ⏫Macrophage #efferocytosis #MERTK signal #FattyAcidOxidation Gabrielle Fredman & Charles Serhan @NatRevCardiol 2024 @GabbyFredman https://t.co/5hqy9MgTGI

HaoYin20's tweet photo. My continued biomedical education

Specialized Pro-resolving Mediators in vascular inflammation and atherosclerotic cardiovascular disease

Lipoxin
Resolvin
Protectin
Maresin

#EndothelialCell-#Neutrophil coordination in SPM biosynthesis🤠

⏫Macrophage #efferocytosis #MERTK signal #FattyAcidOxidation

Gabrielle Fredman & Charles Serhan @NatRevCardiol 2024 @GabbyFredman
https://t.co/5hqy9MgTGI

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Linda Nguyen @LindaNeuN

almost 3 years ago

🎉 Published! 🎉 My PhD work looking at #Mertk in #microglia and #myelination is now published in the Journal of Neuroinflammation @BioMedCentral ! Thank you to @GoodTAMsGoBad, Trevor Kilpatrick, Boris Zalc and all the team for your support and hard work! https://t.co/YoGAbBQOzW

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Marta Delpo @DelpoMarta

about 3 years ago

And here you can check the most important findings of our work on #IRD #IRDgenes #retinaisoforms #5UTR #5UTRcoverage #retina #rarediseases #WES #WGS #noncodingvariation #pathogenic5UTRvariants #MERTK #RDH12 For more, please read the manuscript 🤓 (highly recommended 👌)

Frauke Coppieters @CoppietersF

about 3 years ago

Check out our preprint on combining a prioritization strategy and functional studies to nominate 5'UTR variants underlying inherited retinal disease #IRDs! Excellent work from Alfredo Dueñas Rey @ITN_StarT @DelpoMarta @Bouckaert_M @GenomicsEngland @elfridedebaere.

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JCIM & JCTC Journals @JCIM_JCTC

over 4 years ago

Effective Reaction-Based De Novo Strategy for #Kinase Targets: A Case Study on #MERTK Inhibitors #drugdiscovery https://t.co/377ygfKnYj #current_issue #JCIM #cheminfrmatics

JCIM_JCTC's tweet photo. Effective Reaction-Based De Novo Strategy for #Kinase Targets: A Case Study on #MERTK Inhibitors #drugdiscovery
https://t.co/377ygfKnYj
#current_issue #JCIM #cheminfrmatics https://t.co/E5Gironbu1

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Linda Nguyen @LindaNeuN

over 4 years ago

Thank you @MS_Australia for bringing me to #Hobart for this year’s #MSResearchconf22! Great to be together in person to discuss #RealMSResearch and celebrate #50yearsofprogress! Photo: Dr Vivien Li and I, repping #Mertk with our poster and oral presentation awards 🤘🏻❤️

LindaNeuN's tweet photo. Thank you @MS_Australia for bringing me to #Hobart for this year’s #MSResearchconf22! Great to be together in person to discuss #RealMSResearch and celebrate #50yearsofprogress!

Photo: Dr Vivien Li and I, repping #Mertk with our poster and oral presentation awards 🤘🏻❤️ https://t.co/b8GjQZzjWk

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Cancer Research @CR_AACR

over 5 years ago

Immunotherapies for #BreastCancer might benefit from targeting Axl expressed on tumor cells and #Mertk in the #TumorMicroenvironment, Davra et al @RutgersCancer demonstrate. @quigley_mike @tom_spires https://t.co/v2q5WYS27y

CR_AACR's tweet photo. Immunotherapies for #BreastCancer might benefit from targeting Axl expressed on tumor cells and #Mertk in the #TumorMicroenvironment, Davra et al @RutgersCancer demonstrate. @quigley_mike @tom_spires
https://t.co/v2q5WYS27y https://t.co/APMmmGku4T

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Juan Manuel Ortiz W. @OrtizWilcJM

over 5 years ago

Then, @CintHia_Xn helped us to perform a FAMD resulting in a very clear separation of infected from uninfected patients across Dim1(28.8%), where the main contributors to discriminate them were #TYRO3, #MERTK and #GAS6 together with IgE, Eosinophils and EDSS score #type2immunity

OrtizWilcJM's tweet photo. Then, @CintHia_Xn helped us to perform a FAMD resulting in a very clear separation of infected from uninfected patients across Dim1(28.8%), where the main contributors to discriminate them were #TYRO3, #MERTK and #GAS6 together with IgE, Eosinophils and EDSS score #type2immunity https://t.co/pW4ueNsKIq

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Juan Manuel Ortiz W. @OrtizWilcJM

over 5 years ago

- We noted that circulating monocytes (CD11b high) expressed higher levels of #TYRO3, as did it so DCs (CD1c high), which also showed higher #AXL and #MERTK expression. On the other hand, CD4+ T cells expressed much more #GAS6

OrtizWilcJM's tweet photo. - We noted that circulating monocytes (CD11b high) expressed higher levels of #TYRO3, as did it so DCs (CD1c high), which also showed higher #AXL and #MERTK expression. On the other hand, CD4+ T cells expressed much more #GAS6 https://t.co/NmU4K8lTJY

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MedChemExpress

@MedChemExpress

over 5 years ago

CJ-2360 is an orally active #ALK #inhibitor. CJ-2360 displays potent inhibitory activity against two clinically reported ALK mutants (#C1156Y and #L1196M) and a few other kinases (#LTK, #MERTK, #CLK1, #DAPK1, and #DAPK2). #drugdiscovery. #Monday. https://t.co/8sGTO8pgtc

MedChemExpress's tweet photo. CJ-2360 is an orally active #ALK #inhibitor. CJ-2360 displays potent inhibitory activity against two clinically reported ALK mutants (#C1156Y and #L1196M) and a few other kinases (#LTK, #MERTK, #CLK1, #DAPK1, and #DAPK2). #drugdiscovery. #Monday. https://t.co/8sGTO8pgtc https://t.co/bTmjFJuwe8

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Michelle Williams, PhD @mwilli323

almost 6 years ago

Interesting paper about how targeting #macrophage #MerTk could limit #efferocytosis to improve response of #breastcancer to #immunotherapy

Cancer Research @CR_AACR

almost 6 years ago

Immunotherapies for #BreastCancer might benefit from targeting Axl expressed on tumor cells and #Mertk in the #TumorMicroenvironment, Davra et al @RutgersCancer report. @quigley_mike @tom_spires https://t.co/p5344DoAlD

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Cancer Research @CR_AACR

almost 6 years ago

Immunotherapies for #BreastCancer might benefit from targeting Axl expressed on tumor cells and #Mertk in the #TumorMicroenvironment, Davra et al @RutgersCancer report. @quigley_mike @tom_spires https://t.co/p5344DoAlD

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Norwegian PURE-3® @npure3

almost 6 years ago

@immunoresolvent @rhg_1 @JuliaB_fitness @NatRevImmunol #RvD1 (DHA) promotes efferocytosis in aging by limiting senescent cell‐induced #MerTK cleavage. 2019 "Our results offer an entirely new mechanism whereby senescence promotes defective efferocytosis & this can be therapeutically targeted by RvD1. #AntiAging https://t.co/OPftRdjCj4

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