Norwegian PURE-3®

Ultra-pure true pharmaceutical grade omega-3. Always produced in Norway. The purest omega-3 on the planet.™

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @theSamParr @davidasinclair @NUSMedicine @IRBBarcelona @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab Mechanistically connecting #DNAmethylation & #AntiAging: Recent study confirms 5 g EPA/DHA /day pharma-grade #Omega3 leads to significant hypermethylation (downregulation/silencing) of major aging-related signaling networks in middle-aged women🧬https://t.co/55mLJp0mwC

[Norwegian PURE-3® @npure3]

The relationship of #Omega3 fatty acids with #Dementia and cognitive decline: (@ADNI3study + prospective cohorts): "Our findings support the hypothesis that the efficacy of omega-3 fatty acid supplementation is dose-dependent. We found that omega-3 fatty acid supplementation was significantly associated with a decreased risk of #Alzheimers, particularly among long-term users. The risk of cognitive decline decreased when the intake of omega-3 fatty acids exceeded 1.0 g/d. For this reason, we propose that 1.0 g/d may be the threshold dosage of omega-3 fatty acids for the prevention of cognitive decline." https://t.co/Zzb1Phf8ns

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms @UriAlonWeizmann @IdoAmitLab @AxL_Montagne @ADNI3study A new pre-clinical #BrainAging study indicates DHA have more potent anti-inflammatory effects than EPA. #Aging elevated proinflammatory factors TNFα, IL-1β, IL-6 & increased TLR4 & NLRP3. #DHA attenuated most cytokine changes, but EPA only suppressed IL-6. https://t.co/gGQ1buvMnN

[Norwegian PURE-3® @npure3]

The relationship of #Omega3 fatty acids with #Dementia and cognitive decline: (@ADNI3study + prospective cohorts): "Our findings support the hypothesis that the efficacy of omega-3 fatty acid supplementation is dose-dependent. We found that omega-3 fatty acid supplementation was significantly associated with a decreased risk of #Alzheimers, particularly among long-term users. The risk of cognitive decline decreased when the intake of omega-3 fatty acids exceeded 1.0 g/d. For this reason, we propose that 1.0 g/d may be the threshold dosage of omega-3 fatty acids for the prevention of cognitive decline." https://t.co/Zzb1Phf8ns

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms #Atherosclerosis is a systemic pro-inflammatory/pro-oxidative disease, accounting for a third of deaths globally. New systematic review suggests increasing #Omega3/upper limits of daily intake to improve clinical outcomes/reduce risk of cardiac mortality. https://t.co/xb7vOrTRPT

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms @UriAlonWeizmann @IdoAmitLab New major study of aging human brains shows progression to #Alzheimers disease trajectory starts with lipid/inflammation-related pathways. And @foundmyfitness & @AxL_Montagne have an excellent talk about #Omega3/dementia prevention. https://t.co/L6tfwnV3ZR https://t.co/azzApSMVJy

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms #Atherosclerosis is a systemic pro-inflammatory/pro-oxidative disease, accounting for a third of deaths globally. New systematic review suggests increasing #Omega3/upper limits of daily intake to improve clinical outcomes/reduce risk of cardiac mortality. https://t.co/xb7vOrTRPT

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @IRBBarcelona @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke A new large Atlas of 249 plasma biomarkers for health & disease in 118,461 individuals from the @uk_biobank confirms #Omega3 levels are at top for #AntiAging/disease. The findings were replicated in 5 cohorts in Finland with over 30 000 individuals. https://t.co/QtHADtjOtd

[Dr. Rhonda Patrick @foundmyfitness]

Could there be a critical missing piece to preventing and treating Alzheimer's disease?

New episode with Dr. Axel Montagne (@axl_montagne) suggests dysfunction of the smallest vessels of the blood-brain barrier may be a cornerstone cause of dementia.

https://t.co/OvjtPVm57d

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms And @UriAlonWeizmann/@IdoAmitLab shows #Rejuvenation strategies converge on reduced inflammation & restored fatty acid metabolism. "Argues in favor of directly targeting inflammation & fatty acid metabolism pathways to mitigate age-related health decline." https://t.co/r7jZ1ek3d8

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms @CNSerhanLab: #ResolutionMedicine: are we on track to address the next Pandemic (& #Aging)?
https://t.co/PGTd37HmMd A new high-sensivity method for measuring #Oxylipins/#SPMs: https://t.co/rXEYfbh06u And #Maresin2 (DHA) is another pro-repair molecule: https://t.co/CO11y3tmlt

[Norwegian PURE-3® @npure3]

@philosophising4 @JuliaB_fitness @mdpatrick @thesamparr @davidasinclair @NUSMedicine @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms https://t.co/s3z0jIw7WG

[Norwegian PURE-3® @npure3]

@foundmyfitness @NatureAging @EricVerdin @AkbarLab @Dr_Epel New important study by @ParianteLab et al identifies LOX/CYP450 derived EPA/DHA bioactive lipid metabolites (increased by high-dose #Omega3 administration) as neuroprotective/anti-inflammatory factors for human hippocampal neurogenesis & anti-depression. https://t.co/pfnE0UETtz

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @IRBBarcelona @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke A new large Atlas of 249 plasma biomarkers for health & disease in 118,461 individuals from the @uk_biobank confirms #Omega3 levels are at top for #AntiAging/disease. The findings were replicated in 5 cohorts in Finland with over 30 000 individuals. https://t.co/QtHADtjOtd

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms @CNSerhanLab Previously EPA #ResolvinE1 (RvE1) was shown to be a potent pro-repair molecule and RvE1 & Maresin-2 and their precursors #18HEPE & #14HDHA have been shown to increase dose-dependently in humans by high-purity/concentration EPA/DHA administration. https://t.co/J3OYpDTyxI

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms @CNSerhanLab: #ResolutionMedicine: are we on track to address the next Pandemic (& #Aging)?
https://t.co/PGTd37HmMd A new high-sensivity method for measuring #Oxylipins/#SPMs: https://t.co/rXEYfbh06u And #Maresin2 (DHA) is another pro-repair molecule: https://t.co/CO11y3tmlt

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @IRBBarcelona @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms @BuckInstitute @foundmyfitness @LaukkanenJari @OmegaQuant

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @IRBBarcelona @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @AlwaysOmega3s @FariOmega3 @foundmyfitness @humanageing @USherbrooke @uk_biobank @NgaleHealth @NatureComms «Clustering analyses indicate similar biomarker association patterns across different disease types, suggesting latent systemic connectivity in the susceptibility to a diverse set of diseases.» https://t.co/QK6GZaRrBF https://t.co/O0LP9M6DI0

[Norwegian PURE-3® @npure3]

"In summary, in a global pooled analysis of prospective studies, long chain #Omega3 PUFA levels were inversely associated with risk for death from all causes and from CVD, cancer, and other causes." #AntiAging

[Norwegian PURE-3® @npure3]

@ShangMa5 @valeriavasquezr @LuisOctavioR Very interesting! Also, recently: https://t.co/aMW7jUKmYD

[Norwegian PURE-3® @npure3]

@mdpatrick @JuliaB_fitness @thesamparr @davidasinclair @NUSMedicine @IRBBarcelona @AndreaBMaier @ResetYourClock @DrMorganLevine @LizRose14449371 @OcampoLab @Nature @Cell_Metabolism And a new EPA anti-inflammatory mechanism/target: New study shows EPA is a potent physiological blocker of #VNUT (vesicular nucleotide transporter) that potently alleviates neuropathic and inflammatory pain & insulin resistance. https://t.co/OKOZmALO2B https://t.co/PzxxOvyJFZ

[Norwegian PURE-3® @npure3]

@jacobmhands @JuliaB_fitness @camillebesse @foundmyfitness @DrMorganLevine We now have reasons to suspect that rTG-form #Omega3 may be substantially more potent for Anti-inflammatory effects than other Omega-3 forms. May be especially important regarding #DHA and all-important #NFkB targets for #AntiAging. More to come, also see: https://t.co/RRpZYN5ULn