Top Tweets for #MicroCirculation
Check out our latest issue in @The_InnovationJ! Volume 7, Issue 6 is now online!
https://t.co/O1470PAyJq
#PlanetaryScience #astronomy #biocrusts #biomasswaste #renewableenergy #electricvehicles #OLED #biosensors #LifeSciences #microcirculation #PublicHealth #greenhousewarning #alzheimersdisease #clinicalmedicine #EnergyStorage #LargeLanguageModels #artificialintelligence
If It Doesn’t Look Like a Tree: #Fractals, #Microcirculation, and Why Small Artery Disease Is So Easy to See https://t.co/hLKOu38MWZ
#CoronaryPhysiology
#AbsoluteBloodFlow
#Microcirculation
Outstanding
achievement
thanks to
all🌟 #NURSES
#EuroPcr2026 Presentation:
INOCA/ANOCA:
⏰ 20/05 9:45-10:45
📍The Exchange
Simultaneous
PUBLICATION:
👇
https://t.co/eaifQf0ONm
Beyond the big coronaries, the microvascular network tells the real story of myocardial perfusion.
@MattersoftheH14
#MedTwitter #Cardiology #CoronaryArteries #Microcirculation
📖💡1. Pilot anterior #STEMI: SSO2 halved angio-IMR; benefit concentrated when baseline angio-IMR >40. Toward targeted SSO2 post-PCI. #STEMI #PCI
2. SSO2 cut angio-IMR ~50% in anterior STEMI; biggest gains when baseline >40—signal for stratified use. #Microcirculation #SupersaturatedOxygen
➡️ https://t.co/2Fhsd7cHrT
@GBaronerochette
Comprehensive Physiology ☕ Monday Briefing: NEW PODCAST! 🎧 Li and Liu describe their latest 🐁 research: Functional Segregation of #Pancreatic #Microcirculation Reveals Sex-Dependent #Microhemodynamic Signatures. Listen: https://t.co/3XfW3dEX8c Read: https://t.co/jWKrjrR8Gd
脳微小血管networkをlaplacian行列で解析し実効的な血流増加には複数血管の協調的拡張が不可欠であることを証明
120万個の赤血球を3D追跡する革新的手法で分岐点での血流steal及びphase separation効果をin vivoで初定量化
#microcirculation
#CBF
#papers
https://t.co/aNptxYCP5s
#CoronaryPhysiology
#Atherectomy
#Microcirculation
A T H E R E C T O M Y :
• impact on post-PCI MICROCIRCULATORY indices
• contribution to MYOCARDIAL INJURY
👇
https://t.co/RbdgM0ZIjI
👋
Satoshi Nakawatase
Osamu Iida
@CRMjournal
Feeding has to do with tissue perfusion and uncoupling at interface two. Not whether you are on vasopressors or not. #MicroCirculation.
Do you feed ICU patients on vasopressors? #ISICEM26
Evidence says it can be safe—and lifesaving when patients are adequately resuscitated.
🆕 New paper online today in @SurgicalClinics
Key points 👇
• Vasopressors ≠ automatic contraindication to enteral nutrition
• Dose, stability, and trends matter more than presence alone
• Early trophic EN is reasonable once resuscitated
• Close monitoring for intolerance is essential
• PN remains critical when EN isn’t safe or feasible
Not “feed everyone early” ❌
Feed the right patient, at the right time, the right way ✅
How do you approach feeding patients on pressors in your ICU?
Protocol-driven or individualized?
Read the full paper: https://t.co/eGdw54vR5m
#ICUNutrition #FOAMcc #ICURehab #Dietitian #CriticalCare #SCCMSoMe
On croit que les acouphènes, c’est juste l’oreille ou la tête. Parfois c’est plus bête: le sang circule mal (stress + assis). Genre sirop. Moins d’oxygène, batterie à plat.
#acouphenes #microcirculation #fatiguechronique #sante
https://t.co/JRvZhUvAi4
🧠 REGIONAL ANESTHESIA PARADOX: Why RA ↓ Blood Loss but ↑ Tissue Perfusion
#RegionalAnesthesia #RAEducation #AnesthesiaEducation #UltrasoundGuidedBlocks #MedicalEducation #RegionalAnesthesiaParadox #Microcirculation
#TipOfTheDay #MyRATips
Tip of the Day:
During RA, Surgeons often notice:
🟢 Less bleeding
🟢 Better surgical field
🟢 Improved tissue perfusion
But physiologically
👉 Isn’t vasodilation supposed to increase bleeding?
Let’s decode the paradox.
⚡ CORE CONCEPT
RA simultaneously produces:
⬇️ Macrocirculatory pressure
⬆️ Microcirculatory perfusion
➡️ Same intervention
➡️ Different circulatory levels
🔵 1️⃣ THE MASTER MECHANISM (Sympathetic Blockade) :
RA causes Controlled Sympathectomy
🟡 Local anesthetics block
➡️ Somatic nerve fibers
➡️ Sympathetic efferent fibers
👉 Sympathetic fibers are highly sensitive → functional sympathectomy
🟢 Physiological Consequences
✔ Loss of α-adrenergic vasoconstrictor tone
✔ Arteriolar dilation
✔ Increased venous capacitance
✔ Suppression of surgical stress response
🔬 2️⃣ MICROCIRCULATORY EFFECT (Improved Tissue Perfusion) :
🟢 A. Arteriolar Vasodilation (ARTERIAL END):
Sympathetic blockade causes:
⬇️ Peripheral vascular resistance
⬆️ Capillary recruitment
⬆️ Oxygen delivery
👉 RA improves microvascular perfusion, not large-vessel flow.
🟢 Better tissue oxygenation
🟢 Improved wound healing
🟢 Reduced ischemia
🟢 Enhanced graft survival
➡️ Vasoconstricted tissue → Nutritively perfused tissue
🟢 B. Redistribution of Blood Flow by RA (CAPILLARY BED):
🟢 Opens dormant capillary beds
🟢 Enhances nutritive circulation
🟢 Reduces microvascular shunting
👉 Mild hypotension but effective perfusion increases
🟢 C. Improved Venous Drainage (VENOUS END):
Venodilation produces
🟢 Reduced venous congestion
🟢 Decreased interstitial edema
🟢 Lower compartment pressure
✔ Optimized inflow
✔ Efficient outflow
➡️ Enhanced microcirculation
🩸 3️⃣ WHY LESS SURGICAL BLEEDING
Despite vasodilation → bleeding decreases
🔴 Mechanism 1 - Reduced Perfusion Pressure
RA causes:
⬇️ Controlled hypotension
⬇️ Arterial inflow pressure
🩸 Bleeding ∝ Perfusion Pressure
👉 Lower pressure → Less blood loss
🔴 Mechanism 2 - Stress Response Suppression
Blocking nociceptive input reduces:
⬇️ Catecholamine release
⬇️ Cortisol surge
⬇️ Renin–angiotensin activation
Results:
🟢 Less tachycardia
🟢 Less hypertension
🟢 Reduced capillary bleeding
👉 RA prevents sympathetic surges seen with GA.
🔴 Mechanism 3 - Reduced Venous Oozing
Most operative bleeding is venous.
RA:
⬇️ Muscle tone
⬆️ Venous drainage
⬇️ Venous pressure
👉 Less venous engorgement → Cleaner surgical field
🔴 Mechanism 4 - Improved Surgical Conditions
RA provides:
✔ Muscle relaxation
✔ Hemodynamic stability
✔ Reduced tissue trauma
Consequences:
🟢 Clear surgical planes
🟢 Shorter operative duration
🟢 Secondary reduction in blood loss
⚖️ 4️⃣ MICRO vs MACROCIRCULATION (Resolving the Paradox) :
🔴 Macrocirculation
⬇️ Systemic pressure → ⬇️ Surgical bleeding
🟢 Microcirculation
⬆️ Capillary flow → ⬆️ Tissue perfusion
👉 RA lowers pressure but improves perfusion quality
🌿 5️⃣ PHYSIOLOGICAL ADVANTAGES :
🟢 Improved Oxygen Utilization → Enhanced oxygen extraction
🟢 Reduced Hypercoagulability → Lower thrombosis risk
🟢 Endothelial Protection → Preserved microvascular integrity
🧩 CONCEPTUAL Transformation
FROM
🔴 High-pressure & Poorly perfused circulation
TO ⬇️
🟢 Low-pressure & Well-perfused circulation
⭐ TAKE HOME
RA reduces blood loss despite VASODILATATION via
✔ Sympathetic Modulation,
✔ Microcirculatory Recruitment,
✔ Neurohumoral Attenuation.
That statement isn't entirely accurate. You can directly observe #microcirculation in areas with accessible, transparent tissues, such as the conjunctiva and retina in the eye, the sublingual mucosa, and the skin (nail folds and beds), using specialized devices like vital microscopes, which reveal tiny #capillaries and red blood cell flow, offering a window into systemic vascular health.
This is the basis of one of the most important complementary examinations in #Rheumatology: Nailfold video-#capillaroscopy (NVC). This test allows for the evaluation of the size, morphology, and density of the capillaries in the nail fold, and in some cases, it is even possible to observe the flow of the red blood cell column along the capillary loops.
NVC constitutes a non-invasive biomarker to evaluate #Raynaud's phenomenon, differentiate between primary and secondary, and diagnose early #autoimmune diseases such as scleroderma, dermatomyositis, lupus, and MCTD, detecting microcirculatory changes long before clinical symptoms, predicting organ involvement and evaluating the response to treatment.
📹 Video showing blood circulation in the capillaries of fingers in a patient with diabetes mellitus. The clip was taken with the medical device Capillaroscope, from the portofolio of ONKOCET company medical devices. Credits: Kristian Seffer.
What you see are red blood cells doing their work.
The eye is the only site in the human body where we can directly see this microcirculation. 👁️
IG: dra.vanessa_oftalmologia
#VNS
AI eye scan: narrower retinal arteries flag BMI, BP, clot risk in stable angina, offering window to microcirculation sans invasion. 👁️🩺
@eyetubenet @CooperVision #BMI #BP #microcirculation
Details: https://t.co/goKobxvqXC
🏆 Highly Cited!
17β-Estradiol promotes sex-specific dysfunction in isolated human arterioles
🔬Gopika SenthilKumar, et al.
https://t.co/EfCCMLF2eP
#AJPHeartCirc #HormoneTherapy #Microcirculation #Estrogen
Erst als Fakt kommunizieren, und wenn der Unsinn auffliegt, sagen: Es war nur eine Einschätzung. So wird man berühmt, wie ein Pokal durch die Medien gereicht, fällt die Leiter nach oben, kassiert Orden und bleibt am Ende juristisch völlig unangetastet.
New review with @resiapretorius on #nailfold #capillaroscopy for assessing effects of #microclots on the #microcirculation. Cheap to buy microscope extensions for cellphones. https://t.co/j5oWF05OlQ #TeamClots
In patients with angina and non-obstructive CAD, structural #CMD showed true tissue-level hyperaemic flow restriction independent of subtended myocardial mass, whereas functional CMD does not impair hyperaemic flow once mass is considered.
#Cardiology #Microcirculation #CoronaryPhysiology
https://t.co/WYkrMV4U1L
🫀In #ANOCA patients, coronary microvascular function is usually homogeneous—supporting single-artery testing per guidelines. But some show variation across territories, suggesting multi-vessel assessment may be wise in select cases. #Microcirculation
🔗 https://t.co/Woskk3lm6b
A new review with @resiapretorius on two more imaging methods for measuring effects of #fibrinaloid #microclots on the #microcirculation and endothelial damage. #TeamClots #pwLC #pwME https://t.co/ULgbEfoRkT. Much pricier than #nailfold #capillaroscopy but impactful.
#Microvascular and #microcirculation problems within ocular area resisting conventional treatments for #SARSCoV2. #remdesivir #ME #PAIS #PCS #LongCovid #COVIDー19
Ocular microvascular changes in COVID-19: role of hypoxia, D-dimer, IL-6 and systemic treatment
🔥Interesting Polish study, small, but with a healthy control group, again demonstrating the potential damaging C19 impact on your EYES, especially post hospitalisation!
➡️"In this study of post-COVID-19 patients, no significant differences in density RPC VD were associated with hypertension status or treatment with dexamethasone or remdesivir."
➡️"Vessel density (VD) in specific radial peripapillary capillary (RPC) areas correlated inversely with D-dimer and IL-6 levels, highlighting the need for monitoring peripapillary microvasculature for potential long-term ocular effects of COVID-19."
➡️"These findings indicate that elevated systemic inflammation and coagulation markers may be linked to retinal microvascular alterations following COVID-19, potentially identifying IL-6 and D-dimer as candidate biomarkers for such changes."
➡️"Long-term ophthalmic monitoring may be warranted, particularly in patients with elevated inflammatory and coagulation markers, but further studies are necessary to confirm this need( cfr study limitations)." 1/2
https://t.co/zLkYcRFXod
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