Top Tweets for #NSCLCs
🌟Cancer-Associated Fibroblasts (#CAFs) actively drive resistance to ALK inhibitors in #NSCLCs
💡#Alectinib + #Capmatinib and/or #Cilengitide showed better outcome than single agent in suppressing tumor growth in vivo.
We offer for research use only.
🔥Hot Off the Press | #CAFs actively drive resistance to ALK inhibitors in #NSCLCs
💡#Alectinib + #Capmatinib and/or #Cilengitide showed better outcome than single agent in suppressing tumor growth in vivo
🌟We provide alectinib, capmatinib and cilengitide for research use
Proud to present my poster on #osimertinib efficacy in advanced #NSCLCs harbouring uncommon #EGFR mutations: analysis form Italian biomarker #ATLAS database 🇮🇹 🎯. @myESMO #esmo2025 @pbyronz @PassigliaFra #silvianovello
Nearly 1-2% of #NSCLCs harbor RET fusions. In order to provide characterization & outcome of this rare population, these authors found that patients w/RET+ NSCLC have mainly thoracic & bone disease & potentially improved survival w/specific RET inhibitors. https://t.co/iAACMRMmzS
As a tumor suppressor with aberrant expression in ∼10% of #NSCLCs, SMARCA4 possesses many biological functions.
Check out 'SMARCA4: Current Status and Future Perspectives in NSCLC' on innovative treatment 💉 strategies by SMARCA4 alterations!
🔗 https://t.co/1dwBEtszJw
4) #HER2 mutations were identified in 2006 as oncogenic drivers and are detected in 2-3% of #NSCLCs, more often in ♀️ pts, never-smokers and lung #adenocarcinoma #ADK. HER2 amp & HER2 mutations are distinct molecular targets in 🫁 cancers. See 🔓 https://t.co/ybJvIQ8scv
#Immunotherapy has shown a remarkable contribution to the treatment of #NSCLCs.
But data shows that NSCLCs affected individuals with #RET alteration have lesser PD-L1 and #TMB and are unresponsive towards #ICI drugs.
Read more here:https://t.co/hghE4Wtq3I
#MedTwitter #Genomics
Wonderful news made possible by many great minds-including early work from @ACS_Research Professors Drs. Matthew Meyerson @meyersonlab and Pasi Janne @DanaFarber who 1st showed #NSCLCs with #EGFR exon 20 insertions required alternative treatment strategies https://t.co/u1SdTxQSHJ
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