Top Tweets for #OPSIN
When light hits an opsin in the eye it separates vitamin A. If vitamin A is not recycled by the DHA loop then circadian disease (e.g., inability to sleep, type 2 diabetes, inflammation) results. The leptin prescription & cold thermogenesis protocol
Max Gotzler: "Could you explain the vitamin D and A cycle? […] How does that work in the brain in relation to mitochondria, electrons, and light?"
Dr. Jack Kruse: "Well, this is a pretty complicated story. […] Vitamin D in the brain and vitamin A are yoked, and this goes back to embryology. […] We have something called neuroectoderm. Neuroectoderm is where our brain and our skin come from. In humans that are in fully adult form, there is no direct connection between the skin and the brain.
"Vitamin D and vitamin A bridge that gap, and they are what we call hydrated proteins that act like semiconductors that bring in light. Vitamin D happens to work best with the UVB part of the spectrum that we get from the sun, which is why I wanted Max to ski down the mountain with no clothes on to gain that. […]
"Every opsin in our eye, both in the rods and the cones and also in the nighttime cones called melanopsin, any opsin is bound by vitamin A, and that's called retinol. That's the specific name. In humans (or any animal that's diurnal, meaning that lives in the light) that covalent bond is weak, so anytime light comes in, it separates. When it separates, the vitamin A has to be recycled, and it gets recycled in quantum precision with that DHA loop that I told you in your eye.
"The reason why the eye is incredibly important for vitamin A being yoked, it's been shown in many, many studies that when vitamin A is not yoked properly, the patient will have circadian disease, meaning they won't be able to sleep, they'll have type 2 diabetes, they'll have multiple different problems tied to that. And the reason for that is that connection is the way that the skin and the brain talks to each other by way of light frequencies through the eye. So the brain needs that constant connection, otherwise it cannot tell proper time.
"And when it can't tell proper time, I have an analogy that I use. […] If the deliveries all came at the same day and weren't spaced out appropriately, what would it be like to work at Home Depot at that day? It would be crazy. We would call that chaos.
"What do we call chaos in a cell? Inflammation. And that's the problem. So you need to have the proper yoking within your skin and your eye so the brain is able to tell time. When you can't tell time, that's when you get a circadian mismatch, and that explains to you truly how the leptin prescription and the cold thermogenesis protocol really work, because those things are designed to work in the anterior visual system. Why? The retinas here, the suprachiasmatic nucleus in the middle, and what's distal to that, the leptin receptor. That's a giant semiconductor circuit that allows the human brain to tell night from day, day from night. […]
"DHA is a quantum lipid, and it absorbs light and turns it into an electric current. And really what all our hydrated proteins and lipids do in that circuit act just like a semiconductor. […] Light is used in the system in order to tell time, and that's the key.
"That's why circadian biology is incredibly important to biology. In fact, I think it's the single most important thing. That's why I don't focus a lot of time, Max, talking about food, because it's inconsequential when you understand how important light is in the way that we're put together. And I always tell people that mitochondria, fundamentally, are an electromagnetic sensor for our environment, meaning it's a light sensor, and that's how it's designed to work."
@DrJackKruse with @MaxeeeGeee @ 30:33–35:14 (posted 2017-02-15) https://t.co/3f5eclxtzf
Our study shows that Artificial Light At Night (ALAN) disrupts #zebrafish #circadian clock 🌙💡
In #zebrafish, #ALAN alters daily activity, dampens #clock gene and #opsin rhythms, and drives #circadian arrhythmicity. @UniFerrara @UNI_FIRENZE https://t.co/R476d6dpHf
Our Lepidoptera #opsin story is now out in full print! 🦋
Huge gratitude to all involved, including very helpful input from the reviewers and a smooth publication process with @MolBioEvol
https://t.co/BidodKoWVS
Opsin Elektro Optik'in iş ilanlarını incelemek ve başvuru yapmak için tıklayın ⬇️
🔗 https://t.co/UuzcLuCQ9Y
#VizyonerGenç #Kariyer #İşilanı #Opsin
Opsin diversity and evolution in the Elateroidea superfamily: Insights from transcriptome data: https://t.co/pVoWW32tEC #Elateroidea #Opsin #Phylogeny
In case you missed it, the lab's first #cnidarian paper studying #opsin evolution in the sea anemone #Nematostella vectensis is out! Check it out in EvoDevo! Congrats Kyle and the whole team!
#Evodevo #sensorybiology #evolution
https://t.co/ZYcGU27PF3
How do moths and butterflies see?🦋👀
Our new preprint looks at the evolution of #opsin genes across #Lepidoptera. We uncover fascinating patterns of opsin duplication, translocation, and expression by analysing 219 genomes (most from @darwintreelife)
🔗https://t.co/GgR0qTZeyl
@neuroethology Today's afternoon session is opened with a talk by @MarjorieLienard from @LundVision about the "Functional basis of #insect visual #opsin #evolution" 🦋
#Bisphenol S decreased T3 levels in larval eyes, induced retinal expression of #thyroid hormone receptor β & thereby down-regulated expression of TH-mediated #opsin genes & impaired subsequent phototransduction pathways.
https://t.co/bU4X9DcZJ4
I will not hesitate to follow anyone who follows me, we will grow from the beginning and support each other.
🚀🚀🚀 #NFTCommunity #Web3 #GarbageTalk #garbagefriends #spreadthegoop #opSIN
Me the day before mint waiting to take my chance and join the @operationSIN familly
LET ME IN GUYS
@SINRecruits when me guys
@jerezizzz
@aya_ms888
@Day1Degen
@BIGMANNETH
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#opSIN #vigilante #Sinners #NFTs #freemintNFT
HELLO @operationSIN familly
and G.M to All the familly MODS and their big artist @HatoETH
it really started making me crazy
WEN WL GUYS ?? ??
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#opSIN
#Vigilante #Sinners #NFTs
HELLO @operationSIN FAMILLY
never knew @HatoETH can sing too
really enjoyed it
#vigilante #sinner #opSIN
Good things take time.
Finally day has come
Thank y'all for all the love n support❤️ @operationSIN ❤️
@HatoETH @HelenKellerETH @jerezizzz @Provoker_gm @BIGMANNETH
#SINNERS #opSIN #SINclusion
Just submitted my application for @operationSIN
If you are looking for a project that has a unique art concept, an amazing storytelling & lore, highly experienced team then #opSIN is the one.
Don't forget to check out their website:
https://t.co/DzP2F1IzfG
This is not just an NFT to be minted but is another story to be told. Get ready!!
Join the community
👇👇
https://t.co/pK8qUZbZUE
#gem #opsin #Whitelist #NFTcommunity
I'm in.
Got my @operationSIN codes from @Llamaverse_. The next big thing from @LlamaLabsNFT.
If you like a good mystery, this will be it. Dope Manga style art.
This is going to HUGE!!
Don't fade this!
#opSIN
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