Top Tweets for #OpenTargets
「GWASで関連領域はわかった。でも原因遺伝子はどれ?」
この”最後の1マイル”を解くOpen TargetsのL2Gスコアの解説と、それを使った未探索ターゲット発掘ワークフローを書きました
L2G > 0.5 × Tractable × 未承認 の3条件、シンプルだけど強力です
👉 https://t.co/NInJCq7fOw
#OpenTargets
Open Targets入門 #3 を公開しました📡
OpenTargetsからアルツハイマー病の関連ターゲットの情報を取得するコードを解説。
datatypeスコアの読み方・大量取得時のParquet活用まで。
コードをそのまま使えば、疾患IDを変えるだけで他疾患にも応用できます。https://t.co/SOlnAvEqOu
#OpenTargets
「創薬ターゲット、どうやって選ぶ?」
Open Targets Platformはコード不要、ブラウザだけで疾患→ターゲット探索ができます🔍
スコアの読み方からL2G・Tractabilityまで丁寧に解説👇
#OpenTargets #創薬 #バイオインフォマティクス
https://t.co/INrb90tGHh
Open Targetsとても便利なんですが、
意外と日本語の解説記事がなさそうなので、シリーズで記事書いていこうと思います。
Open Targetsについて
https://t.co/JFxnQAl9fk
#OpenTargets
Looking forward to sharing our #OpenTargets research from the @sangerinstitute 🧬 Illuminating therapeutic targets of neurodegeneration using genome-wide phenotypic CRISPR screens 🧠 on Wednesday at 14:00 in the Four Seasons Ballroom 2-3 at #ASHG24 #ASHG2024 #OpenTargetsAt10 !

🔬 Thrilled to announce our new publication: "Automated Annotation of Disease Subtypes"! Here’s the key takeaways:
#MachineLearning #Bioinformatics #PrecisionMedicine #opentargets #medicalAI
Impact of #Rhesus #bloodtype on the survival of advanced #heartfailure patients with #cardiacresynchronizationthetapy just published in #nature scientific reports. A few potential mechanistic links depicted using bioinformatics platforms #opentargets #ChEMBL

Explore how AI and Open Targets are revolutionizing drug discovery and precision medicine. Check out our latest article: https://t.co/4Twy7mu2qn
#genomics #drugdiscovery #opentargets

Sjoerd, Sander, and Mirella from our Genomics and Target Discovery Team will be at the #aacr2023 Annual Meeting. They would love to answer questions about #opensource solutions to #cancer genomics & drug discovery #CancerResearch #DrugdiscoveryChemistry #cbioportal #opentargets

Two new excellent #dataengineers, Femke Kopmels and Tim Kuijpers, have joined The Hyve team! Femke is now part of the #ResearchDataManagement team, and Tim will be working on #cBioPortal and #OpenTargets. We can’t wait to see what we can achieve together!
#welcometotheteam

📌#HIRING
We are looking for a new colleague to take on the #bioinformatician role in our #OpenTargets team!
Requirements:
- #Python skill
- Bioinformatics domain knowledge
- Eager to learn new technologies e.g. React, Spark
- Fluent in English
Apply now: https://t.co/wxKmHGi82N

Are you interested in learning more about the drug discovery process? Learn about Open Targets and Open Targets Genetics by watching Björn Wouters's talk from the Festival of Genomics 2022 here: https://t.co/BDQHXE4uIQ
#fog2022 #opentargets #drugdiscovery #genetics #gwas
Briefly review of 2021 and coming goals for 2022!
cc: @OpenTargets @SvelteSociety @JotaSolano
#Reactjs #svelte #rust #openTargets
https://t.co/lTigVblXHQ
Finding, validating and ranking new drug targets with #OpenTargets. Explore The Hyve's services around Open Targets and see what we can do for you: https://t.co/hKFtt3Hj81
#targetdiscovery #drugdevelopment #drugdiscovery

The Hyve supports clients in the installation, customization and maintenance of the Open Targets Platform and Genetics Portal and the loading of proprietary data.
Read more our services: https://t.co/isiftxWoce
#OpenTargets #drugdiscovery #drugdevelopment #opensourcesoftware
Fantastic work led by @LiliNYC11 from #OpenTargets & @sangerinstitute + @AnnaCuomo92 & @DanielDSeaton from @EMBLEBI: first #eQTL map at different stages of human neuronal differentiation + hundreds of novel neurological disease-#QTL colocalisations.
https://t.co/EGD46Jt6k0
Very proud of this work. Thanks to this amazing team.
"Services we offer are installation of #OpenTargets system (@targetvalidate), linking the system to clients’ #data, or modifying the application [...] In practice, I’m working as a #datascientist, with a bit of #softwareengineering" #healthIT #opensource https://t.co/POl7OvGl2X
We're celebrating #RandomActsofKindnessWeek highlighting #RandomActsOfKindness that come our way at #OpenTargets.
#RandomActsOfKindnessDay 1: when users take their time to contact our support team to say how useful #OpenTargetsGenetics is & to suggest further improvements.👇👇

Exciting and important research, fantastic team to work with lead by @MayaGhoussaini, great #OpenTargets community. You can make a difference for drug discovery, come join us.
We're looking for a #statisticalgeneticist to develop & apply computational pipelines to find causal genes from #GWAS, eQTL/pQTL, #biobanks. Could this be you? Come & join #OpenTargetsGenetics. #drugdiscovery #OpenTargetsJobs https://t.co/YGNpOdxh42

The Hyve supports clients in the installation, customization and maintenance of the Open Targets Platform and Genetics Portal and the loading of proprietary data. @targetvalidate https://t.co/MIihHl2OBD
#OpenTargets #drugdiscovery #healthdata #bioinformatics #opensource
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