Top Tweets for #Osteolytic

about 1 year ago

#Microgeodic disease is a rare primary #osteolysis disorder characterized by multiple small #osteolytic areas and sclerosis in the phalanges of one or both hands associated with swelling and redness of the phalanges. The term microgeodic was coined by a French radiologist Maroteaux to describe the X-ray finding of very small (< 1mm) punched out lacunar-like osteolytic lesions in the small bones of the fingers of infants affected by this condition. The average age at diagnosis is 7 years. Microgeodic disease usually occurs in the winter months. Patients present with swelling, redness, and sometimes pain in one or more fingers or toes (hands are more commonly affected than feet). Often the clinical changes are described as 'chilblain-like'. The disease course is mostly benign, however, complications such as fracture and digit shortening can occur. While the pathogenesis of this disease is unknown, it is thought to be a transient disturbance of the peripheral circulation caused by cold temperatures. A spectrum of disease with #Raynaud’s and #chilblains at the milder end, and microgeodic disease at the more severe end has been proposed. The differential diagnoses include sickle cell dactylitis, chilblains, spondyloarthritis or infections including cellulitis, osteomyelitis, syphilis and tuberculous dactylitis. The typical imaging findings, best demonstrated on MRI, confirm the diagnosis without the need for biopsy or surgical treatment. *Stranks KF, Tiller G, Liyanage N, Bao D. Microgeodic disease in an infant. BMJ Case Rep. 2022;15(8):e245179. 🔗https://t.co/0TSQn9ZsW8

$alb_giraldo's tweet photo. #Microgeodic disease is a rare primary #osteolysis disorder characterized by multiple small #osteolytic areas and sclerosis in the phalanges of one or both hands associated with swelling and redness of the phalanges. The term microgeodic was coined by a French radiologist Maroteaux to describe the X-ray finding of very small (< 1mm) punched out lacunar-like osteolytic lesions in the small bones of the fingers of infants affected by this condition. The average age at diagnosis is 7 years. Microgeodic disease usually occurs in the winter months. Patients present with swelling, redness, and sometimes pain in one or more fingers or toes (hands are more commonly affected than feet). Often the clinical changes are described as 'chilblain-like'. The disease course is mostly benign, however, complications such as fracture and digit shortening can occur. While the pathogenesis of this disease is unknown, it is thought to be a transient disturbance of the peripheral circulation caused by cold temperatures. A spectrum of disease with #Raynaud’s and #chilblains at the milder end, and microgeodic disease at the more severe end has been proposed. The differential diagnoses include sickle cell dactylitis, chilblains, spondyloarthritis or infections including cellulitis, osteomyelitis, syphilis and tuberculous dactylitis. The typical imaging findings, best demonstrated on MRI, confirm the diagnosis without the need for biopsy or surgical treatment. *Stranks KF, Tiller G, Liyanage N, Bao D. Microgeodic disease in an infant. BMJ Case Rep. 2022;15(8):e245179. 🔗https://t.co/0TSQn9ZsW8$

297

Advances in Radiotherapy & Nuclear Medicine (ARNM) @ARNM_ASP

over 2 years ago

🧐#OpenAccess "Secondary #syphilis: An unusual cause of #osteolytic lesion diagnosed by 99mTc-MDP SPECT and presenting features" 👥By Xia Lu et al. Enjoy reading: https://t.co/uhIbJcpMum

ARNM_ASP's tweet photo. 🧐#OpenAccess "Secondary #syphilis: An unusual cause of #osteolytic lesion diagnosed by 99mTc-MDP SPECT and presenting features"
👥By Xia Lu et al.
Enjoy reading: https://t.co/uhIbJcpMum https://t.co/gePlheH8fm

105

Syed Salahuddin Ahmed @SyedSal55391459

over 3 years ago

#histopath #bone #osteolytic lesion 7-yr. boy Osteolytic lesion of tibia. Photomicrograph. Dx: Fibrous dysplasia.

Sharon Russo @Sharon_russo_

about 4 years ago

(4/7) Furthermore, aged mutant mice developed impressive #SkeletalAlterations. We described polyostotic #osteolytic-like lesions, #wovenbone, cortical #trabecularisation, and #osteosclerotic lesions, consistent with a #pagetic phenotype.

Sharon_russo_'s tweet photo. (4/7) Furthermore, aged mutant mice developed impressive #SkeletalAlterations. We described polyostotic #osteolytic-like lesions, #wovenbone, cortical #trabecularisation, and #osteosclerotic lesions, consistent with a #pagetic phenotype. https://t.co/WGSe55RoOy

Sharon Russo @Sharon_russo_

about 4 years ago

(3/7) In cortical bone of mutant mice, we found #osteolytic lesions, with giant-sized and hyper-activated #osteoclasts (a). We also described altered matrix deposition by P937R mutant #osteoblasts (b), resulting in increased deposition of non-mineralised bone matrix.

Sharon_russo_'s tweet photo. (3/7) In cortical bone of mutant mice, we found #osteolytic lesions, with giant-sized and hyper-activated #osteoclasts (a). We also described altered matrix deposition by P937R mutant #osteoblasts (b), resulting in increased deposition of non-mineralised bone matrix. https://t.co/WX3gmOc9qv

ECTS Academy @AcademyEcts

almost 7 years ago

Latest papers from members of ECTS Academy: "LIGHT/TNFSF14 promotes #osteolytic bone #metastases in non‐small cell #lung cancer patients" by Ilaria Roato in JBMR. https://t.co/E1Hj5rHBoh @ASBMR

Yale Rosen @yro854

about 8 years ago

Left: #Osteolytic vertebral lesions - #MultipleMyeloma Right: #Osteoblastic vertebral metastases - #ProstaticAdenocarcinoma #gross #bone

yro854's tweet photo. Left: #Osteolytic vertebral lesions - #MultipleMyeloma
Right: #Osteoblastic vertebral metastases - #ProstaticAdenocarcinoma
#gross #bone https://t.co/H0DrzQ7053

139

Dr Amanda J. Meyer linkedin.com/in/amandameyerphd @amandameyerphd

over 9 years ago

#Osteolytic & #osteoblastic #spine #metastases from #breastcancer , #lungcancer , #ProstateCancer #RCC doi: 10.4103/2152-7806.182549 #free

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