Top Tweets for #PATINA
Scars and rust once seen as disrespect are now celebrated badges of honor in the car community. These 'war wounds' tell a story of resilience and character. #CarCulture #Patina
Patinar, es una excelente elección para pasar tiempo con tus hijos e incentiva el deporte como forma de vida. #Patina
Có những thứ càng dùng càng đẹp.
Da thật là một trong số đó.
#leathercraft #dathat #patina #handmade #dodathucong
@pfizer Ibrance Combination Receives FDA Approval as a Maintenance Therapy for HR+, HER2+ Metastatic Breast Cancer
#pfizer #ibrance #usfda #approval #maintenancetherapy #metastaticbreastcancer #breastcancer #patina
https://t.co/Nm8zPV24OU
#PATINA got @FDAOncology approved today. #Palbociclib + #trastuzumab ± #pertuzumab + ET as 1L maintenance in HR+/HER2+ mBC. 44.3 vs 29.1 months PFS. A 15-month gain in a chemo-free maintenance phase. Including patients with asymptomatic CNS mets.
And I'm sitting here thinking about the triple-positive patients I started on T-DXd + pertuzumab six months ago.
#DB_09 changed 1L HER2+ in December. Continuous IV every 3 weeks, no defined induction-to-maintenance transition, no THP backbone. If your triple-positive patient is on that regimen, #PATINA doesn't slot in. There is no palbociclib insertion point. The architectures are incompatible.
So today we have two FDA-approved 1L strategies for the same patient, built on fundamentally different structural paradigms. The patient in front of you gets one. You're choosing blind.
PATINA is a real win and the biology is coherent. Congratulations to @Otto_DFCI and the full investigator team.
Metzger O, Mandrekar S, Goel S, et al. N Engl J Med. 2026;394(5):451-462. doi:10.1056/NEJMoa2511218
#BreastCancer #HER2 #MedTwitter
🚨 FDA APPROVAL — palbociclib (IBRANCE) + trastuzumab ±pertuzumab + ET as 1L maintenance in HR+/HER2+ mBC, based on #PATINA (mPFS 44.3 vs 29.1 mo, HR 0.74).
KOL reactions and criticisms + data ↓ https://t.co/CO1f2hPXjB
Leading KOL Voices:
@PTarantinoMD @drsarahsam @OncBrothers @Otto_DFCI @pfizer
🚨 BREAKING: FDA approves palbociclib + trastuzumab ± pertuzumab + ET as 1L maintenance in HR+/HER2+ metastatic breast cancer based on #PATINA! @Otto_DFCI
Median PFS 44.3 vs 29.1 months a >15-month gain for adding a CDK4/6i to anti-HER2 + endocrine therapy after induction. (Any induction approved).
The first phase III trial to show benefit of CDK4/6 inhibition in HR+/HER2+ MBC. #bcsm
Lovely. Just enjoy it as it is. #patina
I’m selling my super-rare 1959 Land Rover SII. I know it looks rubbish but bear with me. This is a one family owned car from new that has never been restored or has any paintwork but it is as solid as a rock. It drives and runs fantastically!
What is rare about it is that this is a very early SII with some cross over Series I features such as the dial vent openers and a split rear tailgate.
Bidding is from £0 and you won’t be disappointed. It even has an EV number plate so it’s green too! Also it has stacks of paperwork but C&C have got the advert wrong and are being slow to change it.
View it here: https://t.co/3bTYni1aLK
**Please share**
Jerry Kleeman’s bagged patina 1949 Chevrolet 3100 step-side
#SolidWhipzTrucks #Patina #Bagged #Chevrolet
Our Patina x Kid Acne T-Shirt in White is now up for pre-order. Support the indie massive and look rad at the same time
https://t.co/Qbq9tJgczz
#patina #kidacne #leicester #shop #shopsmall #graphictshirt #illustration
Great speaking w/ talented actor #MalcolmMays on the final season of @RaisingKanan ; working w/ #Patina Miller (Raq Thomas) & more…
FINAL Season begins June 13 on @STARZ
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