Top Tweets for #PIPPAF_PFA

about 2 months ago

Important data from #PIPPAF_PFA at #ESCCongress, but in my view the primary endpoint—recurrence of any atrial tachyarrhythmia—is a relatively weak measure of treatment effect in persistent #AFib. AF burden may be the more clinically and biologically meaningful endpoint, and notably, the burden data in this study appeared more favorable with PWI (6.9% vs 11%) The larger message, however, is not whether we should empirically add posterior wall isolation to every PVI. We should be moving away from empirical “one-size-fits-all” ablation beyond the pulmonary veins. #AFib is a heterogeneous disease. As we have learned from studies including DECAAF II and #CAPLA, simply adding ablation based on anatomy alone does not necessarily improve outcomes. The challenge is to identify which patient, which atrial substrate, and which target will benefit from additional ablation. The future should be integration of atrial structure and #fibrosis, the spatial and temporal behavior of AF, and increasingly AI-derived phenotyping to individualize what we do beyond PVI—not simply adding another empirical lesion set. Beyond PVI, the question should no longer be “what else should we ablate?” but “who needs additional ablation, where, and why?” #AtrialFibrillation #PFA #AFib #CardiacEP #AI @S_NarayanMD @drjohnm @peterkistler3 @Phiso_de @AndreaSarkozy @TinaBaykaner @DrRoderickTung @purerfellner @TulaneTriad @TulaneHeart

JAMA

@JAMA_current

about 2 months ago

Presented at #ESCCongress: Among patients with symptomatic persistent #AtrialFibrillation, adding posterior wall isolation to pulsed field ablation-based pulmonary vein isolation did not significantly reduce recurrence of atrial tachyarrhythmia compared with pulmonary vein isolation alone. Continuous implantable cardiac monitor follow-up showed recurrence in about half of patients receiving posterior wall isolation and in more than half receiving pulmonary vein isolation alone. 🔗 https://t.co/0nnzLSfwCH

JAMA_current's tweet photo. Presented at #ESCCongress:

Among patients with symptomatic persistent #AtrialFibrillation, adding posterior wall isolation to pulsed field ablation-based pulmonary vein isolation did not significantly reduce recurrence of atrial tachyarrhythmia compared with pulmonary vein isolation alone.

Continuous implantable cardiac monitor follow-up showed recurrence in about half of patients receiving posterior wall isolation and in more than half receiving pulmonary vein isolation alone.

🔗 https://t.co/0nnzLSfwCH

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