Top Tweets for #Poise3
@ElenaG_Bignami #POISE3 by @PHRIresearch @SRAnesthesiaICU was an excellent 2023 publication
In patients having noncardiac surgery, hypotension-avoidance and hypertension-avoidance strategies resulted in a similar incidence of major vascular complications
https://t.co/qDnbulZgIu
@germ_red @BJAJournals @jlvincen @chileanestesia @iceman_ex @Thom_Langer the main results of our meta-analysis (no difference in mortality) are the same when removing the #POISE3 trial…
https://t.co/8Om2JLD3MI
Pooled randomised evidence shows that a target intraoperative mean arterial pressure ≤60 mm Hg is not associated with increased mortality
👨🏻💻🖍️Agree with this correspondence related to @BJAJournals meta analysis on intraoperarive hypotension; all is related to the #POISE3 , where patients spent a median of 0.0 minutes with MAP < 60 mmHg @giovannilandoni @jlvincen @chileanestesia @iceman_ex @Thom_Langer

Long-term antihypertensive therapy in the periop
interrupting 🟰not interrupting
@sranesthesiaicu coordinated the Italian centers participating in the #poise3 RCT
https://t.co/qDnbulZgIu

Look at the effects of interrupting vs non-interrupting chronic antihypertensive medicaments in the perioperative period
we helped randomizing into the #POISE3
https://t.co/B4Lc2rwJoF
Look at the effects of interrupting vs non-interrupting chronic antihypertensive medicaments in the perioperative period
we helped randomizing into the #POISE3
https://t.co/qDnbulZgIu

2/2
In #POISE3 RCT, vascular death, nonfatal myocardial injury, stroke and cardiac arrest at 30 days were identical: 13.9% in the hypotension-avoidance group and 14.0% in the hypertension-avoidance group
#MedTwitter #FOAMcc
https://t.co/FcoTehmSsT

We helped to randomize 7490 pts in #POISE3
In hypotension-avoidance group, intraop MAP target was ≥80 mmHg (before and for 2d after surgery), ACEinhs were withheld and other long-term antihypertensives given only for SBP≥130
Guess the results 1/2 👇
🔗https://t.co/asXwmbYFOw

We helped to randomize 7490 pts in #POISE3
In hypotension-avoidance group, intraop MAP target was ≥80 mmHg (before and for 2d after surgery), ACEinhs were withheld and other long-term antihypertensives given only for SBP≥130
Guess the results 1/2 👇
🔗https://t.co/asXwmbYFOw

@GongGasGirl @doctorhelgi @passing_gas @RCoA and @RCS are advocating tranexamic acid to reduce blood product use following the #POISE3 trial

Are you joining our Twitter Chat focussing on recent @BJAJournals papers on Tranexamic acid tonight at 6pm UK / BST? Send us your questions using the hashtag #bjachat

The haematologist's favourite #Tranexamic acid is widely used in trauma/women's health but use in surgery lags behind despite #POISE3 study. Great to see this important initiative from @RCPhysicians @RCSnews @RCoANews @NHSBT Tranexamic acid for safer surgery: the time is now!👈
If you aren’t routinely using tranexamic acid in surgery, why not? “We have the evidence, we now need to act on it.” The UK Royal Colleges Tranexamic Acid in Surgery Implementation Group. https://t.co/xYrSTscD43

@GongGasGirl @giovannilandoni No. #POISE3 only included patients having more significant noncardiac surgery @ctn_anzca
Prof PJ Devereaux is presenting the #POISE3 @PHRIresearch at #PratoAnaes2022 is it time to give #tranexamic acid to all 300M perioperative patients worldwide?
LET’S REDUCE TRANSUSION BY 20% WITH #TRANEXAMIC acid #TXA
1/
We helped @PHRIresearch in conducting the #POISE3 #RCT published in the @NEJM and presented #ACC22
also #mortality is reduced by 10% in this @NEJM #RCT on #tranexamic acid. This is probably the most important finding
@sedar_es @fabiodoc64 @jaacc_online #poise3 #RCT just completed by @PHRIresearch @SRAnesthesiaICU will give important answers on the management of perioperative medications to minimize hypotension @fabiodoc64 @YukiKotani5 https://t.co/m8hb1aZLc6
#InternationalClinicalTrials Day. These are the trials I have been working on today; @PenguinRct @ITACStrial #POISE3 #ASOSQI (& these studies #PANDA #ASOSPaeds ). Keep pushing for better healthcare for all. @GH_PeriopCare @africanSOS @NIHR_GSU @PHRIresearch @monashperiopmed
@twpainter live at #ASM22PER acknowledging the huge contribution of @ctn_anzca & @POISE3_ANZ to the #POISE3 trial. Thank you to all of the site contributors #whatateam! @gillyormo @katy_skier @ealmaxwell @davimcall @AlliKearney

NZ & Australian POISE-3 sites- tune into @twpainter presenting TxA results of @PHRIresearch #POISE3 trial shortly! @ctn_anzca Late Breaking Trials Sessions at #ASM22PER @ANZCA @katy_skier
#poise3 TXA should be routine
#POISE3 @RACSurgeons @ctn_anzca Tranexamic acid reduces bleeding - mechanistically it cannot cause clots it just stabilises

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