Tom Painter

Anaesthetist. Clinical trials in anaesthesia and perioperative medicine.

[Tom Painter @twpainter]

@TheRealPBarry @ABCmediawatch @Leila_MA There is no doubt that there have, and continue to be war crimes committed. All wars feature them. Atrocities. Israel needs to step away from BN and Gaza need to step away from Hamas and Lebanon from Hezbollah. Ultimately this also means that Iran needs to step away too.

[POISE-3 Australia and New Zealand @POISE3_ANZ]

@twpainter live at #ASM22PER acknowledging the huge contribution of @ctn_anzca & @POISE3_ANZ to the #POISE3 trial. Thank you to all of the site contributors #whatateam! @gillyormo @katy_skier @ealmaxwell @davimcall @AlliKearney

[ANZCA Clinical Trials Network @ctn_anzca]

Call out to all our NZ & Australian POISE-3 sites to tune into @twpainter presenting the TxA arm results of the POISE-3 trial shortly! Learn about the implications to patient care & safety! Thank you for your hard work and dedication! #ASM22PER @ANZCA @PHRIresearch @katy_skier

[ANZCA Clinical Trials Network @ctn_anzca]

The results of the tranexamic acid (TxA) arm of the @POISE3_ANZ #RCT have been published in @NEJM.
The trial definitely showed the benefits of using TxA in non-cardiac surgery patients. Read our press release:
https://t.co/L1Eit81mFS @ANZCA @PHRIresearch @twpainter @katy_skier

[Tom Painter @twpainter]

@shobanarajan51 @ChowdhuryTumul @david__highton Out of an abundance of caution and given the higher seizure rate seen with TXA in the ATACAS trial, these patients were excluded.

[Tom Painter @twpainter]

Translation of our results will be very important @POISE3_ANZ

[Tumul Chowdhury (तुमुल चौधरी) MD, DM, FRCPC, MSc @ChowdhuryTumul]

@david__highton @twpainter All major surgical procedures do not lead to significant blood risks so need to choose TXA wisely (if bleeding risk is significant enough or microhemostasis is a problem etc.) These risks are multi factorial.

[Tom Painter @twpainter]

@ChowdhuryTumul @david__highton But this is impossible to tell beforehand and we have shown there is no downside to using TXA. We also know that blood transfusion is a scarce supply. So why not use a safe and proven drug to prevent it? TXA is safe, inexpensive and proven in all major areas of surgery. @NEJM

[Tom Painter @twpainter]

@david__highton Yes I believe we should. Clear evidence now of reduced bleeding and non-inferiority wrt thrombosis. Lots of secondary analyses yet to come!

[Critical Care at UniMelb @CritCareUniMelb]

Congratulations to Prof Kate Leslie @katy_skier, Dr @twpainter, co-investigators & coordinators at sites across Australia and New Zealand who contributed to the first publication from the @nhmrc funded #POISE3 Trial @PHRIresearch @ctn_anzca @ANZCA @UniMelbMDHS @TheRMH @MischHub

[Tom Painter @twpainter]

@NEJM I believe it should be standard of care in at risk patients undergoing major surgery. The incidence of significant bleeding is often vastly underestimated as is its impact on morbidity and mortality. We also now have evidence that it is non-inferior with regards to thrombosis

[NEJM @NEJM]

Among patients undergoing noncardiac surgery, the incidence of the composite bleeding outcome was significantly lower with tranexamic acid than with placebo. #ACC22 https://t.co/cYIQhE7YCD

[POISE-3 Australia and New Zealand @POISE3_ANZ]

@POISE3_ANZ was only made possible due to the amazing the contribution of our dedicated @ctn_anzca sites. Thank you 🙏🏻 @NEJM @NHMRC @twpainter @katy_skier @ealmaxwellhard @PHRIresearch #ACC22 @AlliKearney @gillyormo @ACTAcommunity @CritCareUniMelb

[ANZCA Clinical Trials Network @ctn_anzca]

Thank you to @katy_skier @twpainter @ealmaxwell for your incredible leadership to run @POISE3_ANZ in Australia and New Zealand. Thank you to @gillyormo @AlliKearney @davimcall for coordinating the trial. @ANZCA @CritCareUniMelb @NEJM @nhmrc @ACTAcommunity #ACC22 #CTN2022 @ANZCA

[Kate Leslie @katy_skier]

Good question 🤔 @david__highton cogPOISE-3 randomizing patients to hypertension-avoidance or hypotension-avoidance should provide a definitive answer @POISE3_ANZ @twpainter @gillyormo @ctn_anzca @CritCareUniMelb @PHRIresearch

[Tom Painter @twpainter]

@SAPoliceNews @abcnews

[Tom Painter @twpainter]

Can I just point out that the car wasn’t driving itself? I think this is unfair to Ford Fairmonts.

[Tom Painter @twpainter]

Can I just point out that the car wasn’t driving itself? I think this is unfair to Ford Fairmonts.

[Tom Painter @twpainter]

@ctn_anzca @ANZCA @POISE3_ANZ 1993. A very long time ago … and my embouchure (Google it) has suffered in the interim! What I would like to know is who else within the @ctn_anzca has musical talents? Maybe we could make a chamber group? 😉

[Tom Painter @twpainter]

A fabulous end to a great meeting @ctn21 @ctn_anzca @anzca. Thank you to all the wonderful people that have made this possible.

[Tom Painter @twpainter]

@POISE3_ANZ

[Tom Painter @twpainter]

Cake wars