Top Tweets for #Protectiontrial
🫀In #CardiacSurgery amino acids infusion prevents AKI.
The infusion must be brief, <48h
➡️ reduced need for RRT
➡️ sufficient to prevent AKI
Less is more!
Read the latest manuscript from the #PROTECTIONtrial, now @BJAJournals
🔗 https://t.co/3hPMjA2hn3
This article on #AMINOACIDS for prevention of #AKI is more important than our @NEJM
Hundreds of centers which are implementing perioperative AA based on the #PROTECTIONtrial and European guidelines should limit the duraton of infusion of AA to<=48 h https://t.co/q7DLwUnxzX
In this secondary analysis of the #PROTECTIONtrial, the renal protective effect of amino acid infusion after cardiac surgery was similar in diabetic and non-diabetic patients, supporting its use for all patients undergoing cardiac surgery.
🔗 https://t.co/FcVufXlEyF
Just published on Journal of Endocrinological Investigation our secondary analysis of the #PROTECTIONtrial
Don't miss: https://t.co/Z5YIn8FVO4
In diabetic pts from the #PROTECTIONtrial, #AminoAcids infusion showed a 97.5% posterior probability of #AKI reduction
The AA beneficial effects don't change in high risk pts!
Dozens of centers worldwide are already implementing AA in routine clinical practice!
What about you?⬇️
it impressive that there is no FDA approved treatment for AKI
#KidneyWk
should the FDA read the #PROTECTIONtrial ?
https://t.co/uLxWyjb29M
One of our latest works with a great mentor, Prof. Rinaldo Bellomo
Intravenous amino acids uniquely protect renal function in cardiac surgery (#PROTECTIONtrial)
AA boost GFR 30-50% in >100 studies
No hemodynamic optimization (SVV/PPV) can match this!
🔗 https://t.co/pv1ldVt96l
Simple, effective, and cost-saving!!
Intravenous amino acids reduce AKI risk after cardiac surgery (~5% ARR, #PROTECTIONtrial)
But that’s not all!!
They also reduce hospital costs in 5 health systems ($184–$2521/pt)
Is your center using AA routinely?
🔗 https://t.co/74Pvl0ypin
@YukiKotani5 high protein intake is likely detrimental for survival of ICU patients
low dose short term AA infusion is beneficial for AKI prevention #PROTECTIONtrial published in @NEJM
Further insights from the #PROTECTIONtrial ✅
@giovannilandoni @PontilloD_ @alessanro_pruna @BaiardoMartina @alebelletti1
A secondary analysis of the #PROTECTIONtrial!
Does #AminoAcids infusion reduce #AKI in #CardiacSurgery patients receiving prolonged-CPB?
Results!✅
⬇️any stage AKI (32% vs 40%, RR 0.79, p<.001)
⬇️stage3 AKI (2.2% vs 5.0%, RR 0.45, p<.001)
🔗 Full text: https://t.co/SQuIgnIjSM
A secondary analysis of the #PROTECTIONtrial!
Does #AminoAcids infusion reduce #AKI in #CardiacSurgery patients receiving prolonged-CPB?
Results!✅
⬇️any stage AKI (32% vs 40%, RR 0.79, p<.001)
⬇️stage3 AKI (2.2% vs 5.0%, RR 0.45, p<.001)
🔗 Full text: https://t.co/SQuIgnIjSM
@YukiKotani5 @NEJM @JAMA_current @CritCareReviews @alebelletti1 @BaiardoMartina we’re now analyzing the #protectiontrial results to see if >48h AA infusion is already dangerous! stay tuned @LosiggioRosario
low dose short term iv aminoacid infusion is beneficial #PROTECTIONtrial @NEJM
Augmented enteral protein during citical illness is bad according to @JAMA_current PUBLISHED TODAY and presented in Belfast @CritCareReviews #CCR25 #TARGETtrial
@alebelletti1 @BaiardoMartina
🚨 Just published our secondary subgroup analysis of the #PROtectionTrial! 🚨
💡 Does IV #AminoAcids infusion still offer #renal protection in cardiac surgery patients with prolonged #CPB?
📌 Full paper https://t.co/NpU7uUUUwO
#AKI #CardiacSurgery #CriticalCare
Excited to present in shortly the role of
➡️Amino acids to prevent AKI
at #ERA25 in Wien 🇦🇹
@ERAkidney
In the meantime you can have a look at the #PROTECTIONtrial
🔗 https://t.co/cBdxReimbh
👏 Stellar presentation by @alebelletti1 on the Protection trial! IV amino acids can reduced AKI in cardiac surgery— key insights, especially for patients with tMCs. Important data, big implications! #Nephrology #ClinicalTrials #PROTECTIONtrial @anzics #prato25
💉 Amino acids were found effective in the prevention of AKI in cardiac surgery
In case you missed the #PROTECTIONtrial ⤵️
🔗 https://t.co/cBdxReimbh
Tomorrow the results will be presented also at #ERA25 🇦🇹 in Wien
🫘The main mechanisms of action of AA on #kidney function in preventing #AKI
Both #tubular and #glomerular factors seem to be involved: they contribute to recruit #RFR
#PROTECTIONtrial
🔗https://t.co/kpArRNvX99
@LosiggioRosario @BaiardoMartina @giovannilandoni @alessanro_pruna
Today at the @Smart_Meeting_M, I had the honor of presenting a secondary analysis of the #PROTectionTrial
There continues to be strong interest in the topic of #AminoAcids for #renal protection in several high-risk settings for #AKI
DM to collaborate with us on it!
Professor @RinaldoBellomo presenting the results of the #PROTECTIONtrial on Amino Acids for AKI 🫘 prevention
Read the full article @NEJM
🔗 https://t.co/cBdxReimbh
and our meta analysis that followed
🔗 https://t.co/2xGpUWKWlE
#ISICEM25
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