Top Tweets for #SACVal
ðŦPRAISE-MR: sacubitril/valsartan in #HFpEF with atrial functional mitral regurgitation #AFMR?
Presented by @S_Dhont at #HeartFailure26:
ð#SacVal improved exercise-induced #PH, âŽïļ mPAP/CO slope vs standard care
ð#ARNI therapy promoted reverse remodeling and blunted the dynamic increase in MR during exercise
ðImprovements were also seen in KCCQ, peak VOâ, NT-proBNP, LV-GLS & LAVI
@escardio @WilfriedMullens @MarcoMetra @jozinetm @HFA_President

ðĻENVAD-HF: 1st prospective RCT of #SacVal in #LVAD #HM3 patientsðŦ
Presented by @MajaCikes
ðLess composite events (deathâ ïļ, worsening kidney function, hypotension, hyperkalemia: 7.6 vs 18.2 /100 pt-yrs
ðSafe, feasible & well tolerated
ð Improved patient-reported outcomes (KCCQâŽïļ)
ðâŽïļneed for additional antihypertensives
SimPub at #JACCHF: https://t.co/MhKWbt3O94
#ESCCongress #advancedHF
@escardio @scottdsolomon #WCCardio

Delighted to have shared the results of ENVAD-HF as late-breaking science at #ESCCongress: 1st prospective RCT of #HeartFailure #GDMT #sacval in #LVADs:
-numerically less primary outcome (death, âŽïļ renal fn, hypotn and hyperK)
-safe, feasible, well tolerated
-improved PROs

ENVAD-HF, a prospective RCT in stable HM3 #LVAD recipients, shows angiotensinâneprilysin inhibition is safe and well-tolerated, paving the way for trials of #HF therapies in this population. https://t.co/NrayztGHvi
#JACCHF #ESCCongress #WCCardio @MajaCikes @scottdsolomon

The SARAH trial tested #SacVal vs placebo to prevent cardiotoxicity from chemotherapy
In this #HREV mini-review we discuss and contextualize the results @victoriavinje @AlbulenaMecinaj âĪĩïļ
https://t.co/CJQS2tXHEg

15) Among #CVdeaths, there was a higher proportion of sudden deaths (45% of CV deaths in the #enalapril group) than due to worsening #HF (https://t.co/t2WjNzDRxr)
#SacVal âŽïļSCD more than enalapril, and the benefit was independent of #ICD
https://t.co/glCjTJ8WAC

#SACVAL
sin diferencias con iECA post IAM
PresentaciÃģn de Marc Pfeffer del Paradise-MI
CÃģmo bajÃģ la mortalidad del IAM desde los '90!
Ahora es mucho mÃĄs difÃcil demostrar reducciÃģn de eventos.
ð§es lo mismo el IAM en 1990 con CPK=30000 y fey20% q el infartito troponÃnico actual?

Reflection of Infinity āļāļīāļāļĢāļĢāļĻāļāļēāļĢāļĒāđāļāļāļŦāļĨāļąāļāļāļāļ Val (1967-2016) āļāļąāļāđāļŠāļāļāđāļŦāđāļāļĄāļāļąāđāļāđāļāđāļ§āļąāļāļāļĩāđāļāļāļāļķāļāļ§āļąāļāļāļĩāđ 14 āļĄāļĩāļāļēāļāļĄ 2021 āļ āļāļēāļāļēāļĢ Arts Centre, SAC Gallery āđāļāļīāļāļāļĢāļīāļāļēāļĢāļāļļāļāļ§āļąāļāļāļąāļāļāļēāļĢ-āļ§āļąāļāđāļŠāļēāļĢāđ āđāļ§āļĨāļē 10.00-18.00 āļ. (āļāļīāļāļāļģāļāļēāļĢāļāļļāļāļ§āļąāļāļāļēāļāļīāļāļĒāđ, āļ§āļąāļāļāļąāļāļāļĢāđ āđāļĨāļ°āļ§āļąāļāļŦāļĒāļļāļāļāļąāļāļāļąāļāļĪāļāļĐāđ)
#sacbangkok
#sacVal

Amazing retrospective of the late sculptor Val at #SACBangkok #SACVal #reflectionofinfinity. Running until March. #ContemporaryArt #bangkok
https://t.co/l5y3ZbuzTT
SPOIL ALERT ðĻ
.
āļāļāļ°āļāļĩāđ āļāļĢāļ°āļāļīāļĄāļēāļāļĢāļĢāļĄāļāļāļ Val āđāļāđāđāļāļīāļāļāļēāļāļĄāļēāļāļķāļ #sacbangkok āđāļĢāļĩāļĒāļāļĢāđāļāļĒāđāļĨāđāļ§āļāļĢāļąāļ ð
.
Reflection of Infinity
āļāļīāļāļĢāļĢāļĻāļāļēāļĢāļĒāđāļāļāļŦāļĨāļąāļāļāļāļ Val (1967-2016)
āļāļąāļāđāļŠāļāļāļāļąāđāļāđāļāđāļ§āļąāļāļāļĩāđ 21 āļĄāļāļĢāļēāļāļĄ-14 āļĄāļĩāļāļēāļāļĄ 2021
.
#sacVal
#RefectionofInfinity

Day 2 Hotline #RCTs #ESCCongress
H/T @AHAScience
#CAD - #trimetazidine vs placebo post PCI
#CKD - #dapagliflozin vs placebo
#HF EF>40% - #SacVal vs placebo
#TAVR - #ASA vs #ASA + #clopidogrel 2/2
@ShrillaB @drsonyaburgess @yaqoub_lina @cardioPCImom @drbrowncares @AnkurKalraMD

#ESCCongress #PARALLAX
And how did we do relative to our predictions on effect of #SacVal on the primary outcomes in in #HFmrEF and #HFpEF?
We (collectively) got one out of two primary outcomes correct! My prediction was spot on though.. just luck!ð 3/3
#PARALLAX #ESCCongress
RCT detailsðð―
#ARNI vs ACEI /ARB /placebo in #HF w/ EF>40% (#HFmrEF #HFpEF)
Your bet on effect of #ARNI vs #ACEI? @DrRajivsankar @foziaahmedMD @Hragy @Sarah_Moharem @HeartOTXHeartMD @EkateriniL @SolovevaAnzhela @DrRaniKhatib @MihaiTrofenciuc @AndreasGevaert
Con ganas de conocer en #ESCcongress que significa que âpor los pelosâ #SacVal no alcanzÃģ significaciÃģn estadÃstica en el objetivo principal de #PARAGON pero aporta beneficios clÃnicos https://t.co/T19MFKQFz9
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