Top Tweets for #Synnotch
ποΈ New podcast episode is out!
Hear, hear and learn (so much!) about #SyntheticBiology, #synNotch & cell-cell-comms from the famous @mikhailshapiro around a paper by the team of @John_A_Ronald!
And discover why @TimWitney dreams of jumping sheep π...
https://t.co/AUxcR8THR8

The authors investigated how synthetically triggered #cytokine circuits could help #CARTcells overcome immunologically cold solid #tumors. They created an #IL2 circuit induced by #synNotch receptors that enabled #microenvironment remodeling and tumor clearance in vivo. (2/4)
#synNotch receptors enable construction of custom sense-and-respond programs in cells. They were developed by members of the Lim and @roybal_lab at CDI, and first published in 2016. We're excited to see the technology out in the wild! #synNotch plasmids are available on @Addgene.

We're excited to highlight recent #synbio #devbio work from the Shanghai Institute of Biochemistry and Cell Biology in @ScienceMagazine. Zhang et al. used CDI-developed #synNotch technology to trace cell-cell contact histories in mouse development.
https://t.co/lwih7SWt79
and now is the turn of @KoleRoybal of @UCSF and @czbiohub. #synNotch all the way for T-cell engineering for cancer and other complex disease. #msbw5
Congrats to our collaborator @KoleRoybal for his outstanding work on the #SynNotch engineering of synthetic signaling modules. @UCSFCancer https://t.co/lNPqEUtv11
Congrats to PICI scientist @KoleRoybal @UCSFCancer for winning inaugural Sartorius @ScienceMagazine prize for his pioneering #SynNotch work in synthetic bio & #Tcell engineering #CARTcell #immunotherapy #celltherapy https://t.co/6FRd3WW8gX
Congrats to PICI scientist @KoleRoybal @UCSFCancer for winning inaugural Sartorius @ScienceMagazine prize for his pioneering #SynNotch work in synthetic bio & #Tcell engineering #CARTcell #immunotherapy #celltherapy https://t.co/6FRd3WW8gX
While #SynNotch results lookvery impressive,it nonetheless lack some of the critical elements to assess its benefits
https://t.co/S6NFmLCUsu

#New analysis: Engineering #Tcells to cellular factories with #synthetic Notch receptors #SynNotch
https://t.co/S6NFmLCUsu

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