Top Tweets for #Syntheticlethality
Read the cover feature of the September 1 issue: Deficiency in POLE Exonuclease Causes #SyntheticLethality in Highly Aneuploid Cancer Cells https://t.co/eA0D8sVyan #GenomeBiology #TumorHeterogeneity #OpenAccess
Learn how #SyntheticLethality could target #ColorectalCancer.
This study shows #ALDH2 inhibition selectively kills APC-deficient tumor cells, revealing a promising precision therapy approach.
#OpenAccess in #GenesAndDiseases: https://t.co/4F6pprp52P
Explaining how Olaparib targets PARP1, 2, or 3
https://t.co/tjTYO4Hmb5
#Olaparib #PARPInhibitor #SyntheticLethality #BRCA #HRD (or #HomologousRecombinationDeficiency)
#OvarianCancer #BreastCancer #Oncology
With the development of novel #MTAcooperative #PRMT5inhibitors, #MTAP deficiency has become an important #target to be exploited through #SyntheticLethality.
Had the opportunity to discuss this at an #educationalsession dedicated to Rare Thoracic Cancers during @myESMO #ESMORareCancers26. Happy to share some key slides and takeaways.
#drugdevelopment @CUHKMedicine #CUHKSarcoma @apoddc @APCLC_2023
A detailed look at synthetic lethality from BRCA–PARP therapy to next-generation SL targets reshaping precision oncology.🧬
Read more:
https://t.co/0HJyzmz7fv
#oncology #syntheticlethality #precisionmedicine #OncoDaily #Cancer #BRCA #PARP_Inhibitors
Looking for more content related to the #AACR25 Major Symposium on #SyntheticLethality? Read this related @MCR_AACR paper on synthetic lethality in HR-deficient #leukemia: https://t.co/CREBMjZbFR @AACR
We’re headed to Chicago! Repare is pleased to announce that we will present two mini-oral and four poster presentations during hashtag#AACR25. Read our press release for more details: https://t.co/U74IG0aIuo #precisiononcology #syntheticlethality #cancerresearch
Recently published:
#PLK1 inhibition induces #syntheticlethality in #Fanconianemia pathway-deficient #acutemyeloidleukemia, by Aditya S. Sheth et al. https://t.co/0mhWwxQBnN
@IUWellsCenter @IUMedSchool @Dr_AmerZeidan #AML #openaccess
Ryvu will present new preclinical data from its #SyntheticLethality pipeline at the 2025 #AACR Annual Meeting in Chicago, April 23-30. Read more: https://t.co/ZryEvGRnGX
Join us for a webinar! Learn more about our progress in RVU120, RVU305, WRN programs, and the ONCO Prime Platform. Register today and be part of the conversation! ➡ https://t.co/zZHwBXreUY
#RyvuTx #SyntheticLethality #DrugDiscovery #RVU120 #RVU305 #WRN #ENA
We are thrilled to present clinical and preclinical data for our four main programs at the 2024 EORTC-NCI-AACR Symposium. Read more: https://t.co/5aI7P5huzS
Download our posters: https://t.co/Heq2yJHCc8
#RyvuTx #ENA #SyntheticLethality #DrugDiscovery #RVU120 #RVU305 #WRN
We're gearing up for the 2024 EORTC-NCI-AACR Symposium in Barcelona! This time, we will present clinical and preclinical data on several programs!
Learn more: https://t.co/WGZAQ9hk9d
#DiscoverForPatients #EORTC #SyntheticLethality #RVU120 #RVU305 #ONCOPrime #WRN #PRMT5
Forging New Pathways In The Fight Against Cancer - Dr. Oren Gilad Ph.D. - CEO, Aprea Therapeutics, joins me on Progress, Potential, And Possibilities #Cancer #Oncology #TumorBiology #OrenGilad #ApreaTherapeutics #Biotechnology #DrugDevelopment #Macrocycles #SyntheticLethality #DNADamageResponse #ATRKinase #WEE1 #Doylestown #Philadelphia #BRCA #PARP #ProgressPotentialAndPossibilities #IraPastor #Podcast #STEM #Innovation #Technology #Science #Research
Forging New Pathways In The Fight Against Cancer - @DrOrenGilad Ph.D. - CEO, Aprea Therapeutics @ProgressPotent1 #Cancer #Oncology #TumorBiology #OrenGilad #ApreaTherapeutics #Biotechnology #DrugDevelopment #Macrocycles #SyntheticLethality #DNADamageResponse #ATRKinase #WEE1 #Doylestown #Philadelphia #BRCA #PARP #ProgressPotentialAndPossibilities #IraPastor #Podcast #STEM #Innovation #Technology #Science #Research https://t.co/7XlWPCdseu
Today at the @myESMO Gastrointestinal Cancers Congress 2024, we're presenting positive new data from our MINOTAUR clinical trial combining lunresertib with FOLFIRI. Learn more here: https://t.co/B6UEJBJC9s #precisiononcology #clinicaltrials #syntheticlethality
CONFERENCE UPDATE: The abstract is available for @RepareRx's presentation at #ESMOGI from the Phase 1 MINOTAUR trial evaluating lunresertib in combination with FOLFIRI. Learn more here: https://t.co/fZtE9un9IT #precisiononcology #syntheticlethality #clinicaltrials
Thrilled to have @FoundationATCG as a partner in helping us genomically match the patients who will most benefit from our new medicines! #precisiononcology #syntheticlethality
We are collaborating with @FoundationATCG to deliver genomic profiling to patients in our lunresertib clinical trials and beyond. We are thrilled to take this next step with potential to develop a companion diagnostic and expand access to clinical trial sites for lunresertib.
Join @RepareRx's management team in a fireside chat at the @GoldmanSachs 45th Annual Global Healthcare Conference in Miami. Check out our webcast to hear the latest updates: https://t.co/35B3BoxXWC #syntheticlethality #clinicaltrials $RPTX
PUBLICATION ALERT: we are proud of our team and collaborators for continuing to advance our ATR inhibitor, camonsertib. Learn more here: https://t.co/9sRwwyKviB. #syntheticlethality #biotechcollaboration #precisiononcology
So pleased to see @AlexMMutch from the @Lappin_Lab_QUB presenting his cool synthetic lethality PhD project so well!! Well done! @LAL_NI @QubPGJCCR #CRISPR #SF3B1 #syntheticlethality
Congratulations to Alex Mutch @Alex_Mutch_ @QUBBloodCancer for winning best oral presentation #YoungEHA #BSH2024 @britsochaem discussing spliceosomes in MDS/AML. Congrats to all speakers and poster winners too!
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