Top Tweets for #PLK1
Research Article by P Singh et al. (@vardhanediga @UCincyMedicine) #PLK1 inhibition by #volasertib suppresses key transcriptional regulators underlying #fibroblast activation and #pulmonary #fibrosis
https://t.co/XwLEffdnT5
🔬 Antibody of the Week: AbFlex® PLK1 antibody (rAb)
Meet our AbFlex® PLK1 antibody, part of our AbFlex recombinant antibody (rAb) collection [https://t.co/Hxs8rUbH53]
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#AntibodyOfTheWeek #Epigenetics #ActiveMotif #AbFlex #PLK1 #RecombinantAntibody #Research
![activemotif's tweet photo. 🔬 Antibody of the Week: AbFlex® PLK1 antibody (rAb)
Meet our AbFlex® PLK1 antibody, part of our AbFlex recombinant antibody (rAb) collection [https://t.co/Hxs8rUbH53]
_______
#AntibodyOfTheWeek #Epigenetics #ActiveMotif #AbFlex #PLK1 #RecombinantAntibody #Research https://t.co/PeFWyACTYP](https://pbs.twimg.com/media/G5fsx4tbcAM9ubk.jpg)
Wohaaa! 🤯🤯🤯
Playing polo (#Plk1) outside de pitch. Another great example on how mitotic genes perform important roles outside the cell cycle. And again Plk1, what an amazing enzyme!
Activation of polo-like kinase 1 correlates with selective motor neuron vulnerability in familial ALS https://t.co/I0xRCc18lF
#ASCO25 #MetastaticBreastCancer Poster Session:
A phase 1b study of #Plk1 inhibitor onvansertib in combination with paclitaxel in metastatic triple-negative breast cancer (#mTNBC) patients.
Abstract 1100 | Poster Bd 79 | 9-12 PM CDT | Hall A
@antgiorda @stolaney1 @drsarahsam @nlinmd @KristinaFanucci @elmayermd @FilipaLynce @GShapiroMDPhD @JinQingchun #MBC
Recently published:
#PLK1 inhibition induces #syntheticlethality in #Fanconianemia pathway-deficient #acutemyeloidleukemia, by Aditya S. Sheth et al. https://t.co/0mhWwxQBnN
@IUWellsCenter @IUMedSchool @Dr_AmerZeidan #AML #openaccess
Recently published:
MYC and #HSF1 Cooperate to Drive Sensitivity to #PLK1 Inhibitor Volasertib in High Grade Serous #OvarianCancer, by Imade Williams et al. https://t.co/GqI9z3foX7
@carpenter_lab @JoeRDelaney1 @kennyneph @IUMedSchool @IUCancerCenter #HGSOC #openaccess
Chronic myelomonocytic leukemia: molecular pathogenesis and therapeutic innovations [Oct 17, 2024] @LudovicaMarando @ccsizmar @MrinalPatnaik @Haematologica https://t.co/7WzEEEFW3L #leusm #CMMLsm #PrecisionMedicine #KRAS #NRAS #SHP2 #PLK1 #WEE1 @MayoCancerCare
![mtmdphd's tweet photo. Chronic myelomonocytic leukemia: molecular pathogenesis and therapeutic innovations [Oct 17, 2024] @LudovicaMarando @ccsizmar @MrinalPatnaik @Haematologica https://t.co/7WzEEEFW3L #leusm #CMMLsm #PrecisionMedicine #KRAS #NRAS #SHP2 #PLK1 #WEE1 @MayoCancerCare https://t.co/mS3ZnR5eTP](https://pbs.twimg.com/media/GcDeQzeXgAAMM1N.jpg)
Are you interested in understanding how #RAS mutations could be targeted in #CMML please read our review in @Haematologica by @LudovicaMarando and @ccsizmar #KRAS #NRAS #SHP2 #PLK1 #WEE1 @MayoCancerCare
Cardiff Oncology’s Onvansertib is a novel investigational PLK1 inhibitor in combination therapy for Relapsed or Refractory Acute Myeloid Leukemia. Chemenu supplies novel building blocks https://t.co/lIWzNTWoWS
#PARP #Inhibitors #PLK1 #Molecules
#Cancer #KRAS #Colorectal #CRC
How do #cellcycle oscillators generate exactly two #meiotic divisions to produce haploid gametes?
Wolfgang Zachariae and coworkers @MPI_Biochem show that #Spo13/#MEIKIN and #Cdc5/#Plk1 cooperate to prevent premature APC/C-Ama1 activation after #meiosis I
https://t.co/TmODGOz0QA
#PLK1 and #PP2A-B56 form a bifunctional #kinase-#phosphatase module that balances mitotic checkpoint strength and #kinetochore-microtubule attachment dynamics
#RefereedPreprint c/o @ReviewCommons by @Andrea_Corno_ @AdeSaurin et al @Dundeeuni
https://t.co/S4Y1Mk885d
#TrendingWithImpact: On June 27, 2023, researchers Lilia Gheghiani & Zheng Fu from @VCU published a new #editorial in #Oncotarget, entitled, “The dark side of PLK1: Implications for cancer and genomic instability.”
DOI: https://t.co/Zn48loRn1L
#GEMmodel #PLK1 #openaccess #medEd
UBAP2L-dependent coupling of #PLK1 localization and #stability during #mitosis.
https://t.co/v2mdcTfEMY
Et voilà! Here’s is our story on how #UBAP2L regulates localization and stabilty of Polo-like kinase 1 #PLK1 during #mitosis. Big thank you to all authors but especially to @LucileG2 and @EvaPangou as well as to the reviewers and the editors at the @emboreports 😁🙏
Et voilà! Here’s is our story on how #UBAP2L regulates localization and stabilty of Polo-like kinase 1 #PLK1 during #mitosis. Big thank you to all authors but especially to @LucileG2 and @EvaPangou as well as to the reviewers and the editors at the @emboreports 😁🙏
Our paper on the new pathway that regulates the ubiquitin-mediated turnover of Polo-like kinase 1 in mitosis is now published in EMBO Reports! @SumaraLab @IGBMC https://t.co/gScPl7r6iD
Very happy to share our revised preprint on the role of #UBAP2L in coupling #PLK1 localization and stability during #mitosis . Thank you 🙏 to all authors but especially to @EvaPangou and @LucileG2 https://t.co/SJSv27HhAP
Announcing #MC210807 Phase 1 clinical trial testing safety and efficacy of #Onvansertib #oral #PLK1 inhibitor for R/R proliferative #CMML #RAS . Please DM for referrals @MayoCancerCare @aamdsif @MDSFoundation @md_padron @Dr_AmerZeidan @LLSResearch @KB_McCullough @AlkaliDr
The enzyme #PLK1 amplifies cancer-associated MAPK signaling and supports the growth of lung cancer but can be targeted with approved therapeutics, shows new preclinical research from a team at @universityofky. https://t.co/1e8DZKAjvO
The enzyme #PLK1 amplifies cancer-associated MAPK signaling and supports the growth of lung cancer but can be targeted with approved therapeutics, shows new preclinical research from a team at @universityofky. https://t.co/yhCldDFmLY
1/ We've made important progress in advancing our novel #PLK1 inhibitor, #CYC140, into a Phase 1/2 study for the treatment of solid tumors & #lymphomas. Interested in learning about our third protocol 140-101 and what is next for CYCC140? Thread below.🧵 $CYCC
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