Top Tweets for #Targetedproteindegradation
A new study in Cell Chemical Biology explored how the mechanism driving oncogene overexpression can determine the effectiveness of protein degraders such as PROTACs.
Link in the comments 👇
#TargetedProteinDegradation #PROTAC #CancerResearch #DrugDiscovery #Oncology
New bioRxiv preprint: covalent remodeling of CRBN locks His353 in a conformation that avoids the IMiD clash and polarizes the C2–H to form a new edge‑to‑face interaction with NTAQ1 Phe126. #TargetedProteinDegradation #MolecularGlue https://t.co/g331OlG1PL
#ProteinDegraders are opening new doors in #DrugDiscovery. We support this work with high-quality biospecimens, advanced in vitro systems, and scientific expertise to help ensure your data is both relevant and regulatory-ready. https://t.co/R18nAgpnVy
#TargetedProteinDegradation
2nd virtual #roundtable with #Poland #biotech #CaptorTherapeutics $CTX #TargetedProteinDegradation (Market cap EUR 104m) on #AIRTIMESoftware on February 6 at 11:00 https://t.co/kLBfCbikbZ
Call with #CaptorTherapeutics $CTX #Poland #TargetedProteinDegradation #stocks #clinicalphase (Market cap EUR 108m) on Thursday, January 15, at 11:30 https://t.co/lYb0cg4m49
Nurix Therapeutics Presents New Data from P-I of Bexobrutideg (NX-5948) in Relapsed/Refractory CLL at ASH’25
#nurixtherapeutics #bexobrutideg #nx5948 #cll #sll #pia #pib #rp2d #btkinhibitor #targetedproteindegradation #ash2025 #oncology #pharma
https://t.co/jWeBGUDAfN
We’ll be presenting at the 8th annual @HansonWade #TPD & Induced Proximity Summit & look forward to discussing all things #targetedproteindegradation!
Check out the full program: https://t.co/ejRwa5njL1
Thank you @BioCentury and @SelinaMKoch for featuring our Founder & CEO, @NelloMainolfi, on the #BioCenturyShow.
In this episode, Nello discusses the science and strategy of #TargetedProteinDegradation—its unique catalytic mechanism, ability to reach historically undrugged targets, and the challenges and opportunities that come with translating a new modality into meaningful therapies. He also highlights Kymera’s industry-leading work in immunology, where oral degraders like KT-621, our STAT6 degrader, can unlock new possibilities for millions of patients.
Listen to the full episode here: https://t.co/6nF7e7xils
#RevolutionizingImmunology
We’re excited to announce two partnership updates across our portfolio of novel oral degrader programs, both showcasing our innovation in the field of #targetedproteindegradation.
We’ve entered into a strategic collaboration with Gilead Sciences to accelerate the development and commercialization of our first disclosed molecular glue degrader program targeting CDK2, a high value oncology target with broad treatment potential in areas of significant unmet need.
Additionally, our partner Sanofi intends to advance KT-485, an oral, highly potent and selective development candidate targeting IRAK4 for immuno-inflammatory diseases that Kymera has discovered and characterized through preclinical studies, into clinical studies and will direct all collaboration resources to this next-generation IRAK4 degrader.
Read the full press releases here: https://t.co/qQx6j1PWVr
A landmark session concluded successfully at #CSIRIIIM #Jammu: Dr. Serge Mignani's lecture on #TargetedProteinDegradation explored cutting-edge approaches like #PROTACs vs #MolecularGlues. Grateful for the robust participation and engagement. #DrugDiscovery #ScienceInnovation #MedicinalChemistry #Sanofi #France
Do you find multi-step #PROTAC synthesis to be laborious and time-consuming? We present our latest work in @ChemCommun on a microwave-assisted #SNAr methodology for rapid preparation of #pomalidomide-based #PROTACs!
#targetedproteindegradation #molecularglues
Take a look at 'Microwave-assisted synthesis of pomalidomide building blocks for rapid PROTAC and molecular glue development'
New from Patrick Gunning and colleagues at @GunningLabUofT
https://t.co/URQzvQhoNo
Inspired by @FleurMFerguson and all speakers getting Tuesday started off right! @KeystoneSymp #KSProxDrugs25 #targetedproteindegradation
🤝 #MeetOurScientists: Dr. @CrisMayorRuiz
🎯🔬 Learn how Dr. Mayor-Ruiz's pioneering work in #TargetedProteinDegradation is unlocking new ways to treat untouchable diseases.
📽️ Watch now and explore the future of #biomedicine!
#IRBScience #ProteinDegradation #TPD
Research Scientist - Mass spectrometry - Ferguson Lab @FleurMFerguson
Join our team working on #targetedproteindegradation #chemicalproteomics #molecularglues as a mass-spectrometry specialist in the Ferguson lab at UCSD
To read the full job description and apply, see link i...
Online now - the Review "Routes to #MolecularGlueDegrader discovery" from Yanfen Liu, Yong Cang, and colleagues.
#MGD #TargetedProteinDegradation #TPD #PROTAC #HighThroughputScreening
https://t.co/vFq83vbsne
📰👀 Check out this thread about the new #preprint by our #TargetedProteinDegradation & Drug Discovery lab (Dr. @CrisMayorRuiz) around oncoprotein degradation in vivo, in collaboration with @lab_santamaria- @ciccancer!
📌DOI: https://t.co/DvGsdKHn9c
#TPD #KRAS
🧵👇
We are thrilled to share our new preprint around oncoprotein degradation in vivo —a fantastic collaboration with our friends in Salamanca @lab_santamaria @ciccancer! 😃 @IRBBarcelona #TPD #KRAS
👇
https://t.co/EFZBWFoNHg
E3 Ligase attach a small tag (called ubiquitin) to a substrate protein that needs to be removed by proteassome. #E3Ligase #ProteasomePathway #Ubiquitin #TargetedProteinDegradation
Find out more about the partnership on our website: https://t.co/gVTb3GdG9z
#TargetedProteinDegradation #IntegratedDrugDiscovery
Deadlines are approaching for @KeystoneSymp Proximity Based Therapeutics: #TargetedProteinDegradation and Beyond, this February in Santa Fe! See scholarship, abstract and discount reg dates: https://t.co/JuL40EfGNQ #KSProxDrugs25
🤝 #MeetOurScientists: Dr. @CrisMayorRuiz
🎯🔬 Learn how Dr. Mayor-Ruiz's pioneering work in #TargetedProteinDegradation is unlocking new ways to treat untouchable diseases.
📽️ Watch now and explore the future of #biomedicine!
#IRBScience #ProteinDegradation #TPD
Last Seen Hashtags on Sotwe
incesto papá hija
Seen from Peru
anxiouspandaa(*) + filter:native_video
Seen from Canada
นักเรียนมัธยม
Seen from Thailand
lo鞋鞋交
Seen from Germany
brosis
Seen from Sweden
دوري_ملكات_الاغراء
Seen from Italy
Soaking
Seen from Turkey
Playboi
Seen from United States
cum #mouth
عمه_للكلابُ
Seen from Saudi Arabia
Most Popular Users
Elon Musk 
@elonmusk
241.5M followers
Barack Obama
@barackobama
118.8M followers
Cristiano Ronaldo
@cristiano
114.5M followers
Donald J. Trump
@realdonaldtrump
111.8M followers
Narendra Modi
@narendramodi
107.1M followers
Rihanna
@rihanna
98.7M followers
NASA
@nasa
92.3M followers
Justin Bieber
@justinbieber
91.8M followers
KATY PERRY
@katyperry
90M followers
Taylor Swift
@taylorswift13
84M followers
Lady Gaga
@ladygaga
75.5M followers
Virat Kohli
@imvkohli
73.5M followers
Kim Kardashian
@kimkardashian
70.9M followers
YouTube
@youtube
68.8M followers
Neymar Jr
@neymarjr
66.5M followers
Bill Gates
@billgates
65.3M followers
Selena Gomez
@selenagomez
63.1M followers
The Ellen Show
@theellenshow
62.2M followers
CNN
@cnn
61.7M followers
X
@x
60.7M followers