Top Tweets for #Trim28
Lots of novel neurological #MorbidGenes from ECRs in Room A3 this evening #eshg2024 🧠
Laura Castilla-Valmanya - #TRIM28 causes AD NDD via silencing TEs
Maria Cerminara - AD #FAN1 variants (inc whole gene dels) cause NDD,
Valentina Serpieri - #TTL causes AR tubulinopathy
🔬Publication - by Dr. Ching-Jin Chang, Steven Lin, Shu-Yu Lin, Sheng-Wei Lin @MDPIOpenAccess
#TRIM28 is a crucial #epigenetic modifier, and this study suggests that (de)acetylation of K304 in TRIM28 alters its interaction with #zincfinger proteins. https://t.co/6UR1d1gk46
Co-crystal structure of the ZBF39 and #KAP1/#TRIM28 allows validating the importance of KRAB domain binding by KAP1 for genome-wide transcriptional repression at thousands of loci
@yorgomodis and collaborators @Cambridge_Uni
https://t.co/4ShyiHzG8z

🔬Publication - by Dr. Sheng-Wei Lin, Steven Lin, Ching-Jin Chang @MDPIOpenAccess
This study demonstrates the regulatory network of #TRIM28-mediated #cellgrowth and #erythroid #differentiation in #K562 #leukemia cells. https://t.co/prKGQ0HFiT
#biochem #biochemistry #knockout
🔓 #OA
Identification of #SUMO Targets Associated with the Pluripotent State in Human Stem Cell
➡️https://t.co/PMSZiS11Sg
@UoDLifeSciences @GREDundee Dr Barbara Mojsa, Dr Michael Tatham, Dr Lindsay Davidson, Magda Liczmanska, @EmmaBranigan Prof Ronald Hay
#TRIM28 #proteomics
"Disruption of #RING and PHD Domains of #TRIM28 Evokes Differentiation in Human #iPSCs" by #PUMS Mazurek et al. in @Cells_MDPI https://t.co/l7iek6IGns
#oncotwitter #CellBiology #stemcells #iPS #KAP1 #stemness #epigenetics #Cancer
Activation of endogenous #retroviruses by #Trim28 deficiency during brain development causes #microglia activation and #ERV protein accumulation in adult mouse brains – study by @JakobssonLab @Lund_Stem and coworkers
https://t.co/khFBRvdcrW

Cool research from my awesome new colleagues
#epigenetics
#endogenousretrovirus
#KAP1
#TRIM28
https://t.co/LIni9gGbBK
Read about how the activation of ancient viruses during brain development may contribute to brain disorders later in life #transposons #inflammation #braindisorders @Crocheholic @JakobssonLab @medfak_LU @embojournal
Click here to find out more 👉https://t.co/qfAoT7UDC6

#ScienceJustRight
Beautiful talk by Steve Goff from @ColumbiaPS here @UMassMedical to discuss #Retroviruses #TranscriptionalSilencing #TRIM28 #ZFP809 #HUSHComplex #NP220

#TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes #ProstateCancer progression. https://t.co/zQWigleOC8
We found TRIM28 to interact with AR (https://t.co/Bl1jDbSvt5)
But we never published it, but we also found reduced LNCaP proliferation in TRIM28 KO cells!
Wonderful to see this work by Dept Pathology #PhD student Ben Halliday published in @PLOSGenetics - check out the paper here #TRIM28 #WilmsTumour #kidneycancer #childhealth
https://t.co/Cp3GO8hU0A https://t.co/IzF5UtXeYw
Otago scientists in Dept Pathology make breakthrough in childhood kidney cancer - paper published in @PLOSGenetics #WilmsTumour #KidneyCancer #TRIM28 ping @geneticsotago https://t.co/JUsSuRKxii https://t.co/Cp3GO8hU0A
#NewResearch on germline mutations and somatic inactivation of #TRIM28 in #Wilms tumour from Halliday et al https://t.co/9El44BEpkY

Great video explaining importance of #Trim28 paper @CellCellPress paper to general public! https://t.co/zVG8iPvUlf

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