Top Tweets for #Zoledronate
#Zoledronate to prevent postmenopausal fractures has a prolonged duration of action. Can less frequent administration prevent vertebral fractures in early postmenopausal women? Summary of an RCT in @NEJM
https://t.co/2lhmhh2jy8
#EvidenceMatters #bonehealth #womenshealth
Hoy en #Difundiendo_con_hueso🦴, #Zoledronate administrado cada 5 años reduce fracturas vertebrales en mujeres posmenopáusicas tempranas (NNT 21). Efectivo incluso con dosis infrecuentes (NNT 22). 🩺 #Osteoporosis en @NEJM https://t.co/YxPMSPufSx
Buen miércoles 😁
Treatment for post-menopausal women facing #osteoporosis. #Zoledronate: A Game Changer in Bone Health Management https://t.co/pDcrUg3QCr
Für die #Prävention von #Wirbelfrakturen bei Frauen in der frühen Postmenopause aber ohne #Osteoporose ist das Bisphosphonat #Zoledronate offenbar im mehrjährigen Verabreichungsintervall wirksam.
https://t.co/DBKjnlRZKl
In a recently published randomized clinical trial of 101 participants who received #denosumab for 2 or more years, sequential therapy with #zoledronate did not prevent loss of #bone mineral density in the lumbar spine (LS-BMD) in the first year. In multivariable and subgroup analyses, a longer duration of denosumab use was associated with further decreased LS-BMD; however, BMD in the femoral neck and total hip was preserved after sequential therapy. These findings suggest that sequential therapy with zoledronate does not fully prevent a decrease in LS-BMD after denosumab discontinuation.
*Lee C, Wang C, Yen H, et al. Zoledronate Sequential Therapy After Denosumab Discontinuation to Prevent Bone Mineral Density Reduction: A Randomized Clinical Trial. JAMA Netw Open. 2024;7(11):e2443899.
🔗https://t.co/F1Ag3nuh3z
Duration of #fracture prevention after #zoledronate treatment in women with #osteopenia: observational follow-up of a 6-year randomised controlled trial to 10 years https://t.co/RuyuGjo4fK #osteoporosis
#WorldOsteoporosisDay
Duration of #fracture prevention after #zoledronate treatment in women with #osteopenia: observational follow-up of a 6-year randomised controlled trial to 10 years https://t.co/RuyuGjo4fK #osteopenia
"Optimal #fracture prevention with #zoledronate requires its ongoing administration. In this study, the slow increase in fracture rates after treatment cessation suggests that interdose intervals of longer than 18 months might be effective" https://t.co/RuyuGjoC5i #osteopenia
Matthew T Drake comments on:
Optimising #zoledronate treatment holiday duration without loss of #fracture prevention https://t.co/LoCPBuF2wp #osteopenia
Duration of #fracture prevention after #zoledronate treatment in #women with #osteopenia: observational follow-up of a 6-year randomised controlled trial to 10 years https://t.co/RuyuGjo4fK #osteopenia
Duration of #fracture prevention after #zoledronate treatment in #women with #osteopenia: observational follow-up of a 6-year randomised controlled trial to 10 years https://t.co/RuyuGjo4fK #osteopenia
Optimal #fracture prevention with #zoledronate requires its ongoing administration. In this study, the slow increase in fracture rates after treatment cessation suggests that interdose intervals of longer than 18 months might be effective https://t.co/RuyuGjo4fK #osteopenia
Optimal #fracture prevention with #zoledronate requires its ongoing administration. In this study, the slow increase in fracture rates after treatment cessation suggests that interdose intervals of longer than 18 months might be effective https://t.co/RuyuGjo4fK #osteopenia
Duration of #fracture prevention after #zoledronate treatment in #women with #osteopenia: observational follow-up of a 6-year randomised controlled trial to 10 years https://t.co/RuyuGjo4fK
#WomensHealth #menopause #osteopenia
In the Current Issue:
Duration of #fracture prevention after #zoledronate treatment in #women with #osteopenia: observational follow-up of a 6-year randomised controlled trial to 10 years https://t.co/RuyuGjo4fK #osteopenia
In the April Issue:
Duration of #fracture prevention after #zoledronate treatment in #women with #osteopenia: observational follow-up of a 6-year randomised controlled trial to 10 years https://t.co/RuyuGjo4fK #WomensHealth
In the Linked Comment, Matthew T Drake comments on:
Optimising #zoledronate treatment holiday duration without loss of #fracture prevention https://t.co/LoCPBuF2wp #osteopenia
Optimal #fracture prevention with #zoledronate requires its ongoing administration. In this study, the slow increase in fracture rates after treatment cessation suggests that interdose intervals of longer than 18 months might be effective https://t.co/RuyuGjo4fK #osteopenia
Optimal #fracture prevention is likely to require ongoing use of #zoledronate beyond 6 years, and it is possible that administration at intervals of more than 18 months might be adequate https://t.co/RuyuGjo4fK #osteopenia
Also read the Linked Comment by Matthew T Drake:
Optimising #zoledronate treatment holiday duration without loss of #fracture prevention https://t.co/LoCPBuF2wp
#osteopenia
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