Top Tweets for #Zoledronic
The #early and multiple #Zoledronic injections are needed better to preserve #BMD after #stopping #Dmab in #longterm users.
#Osteoporosis #sequentialtreatment #DXA
https://t.co/yGFSmIAPRn
GLAND PHARMA RECEIVES USFDA APPROVAL FOR ZOLEDRONIC ACID INJECTION
Link: https://t.co/rF8fTRvf2z | News: Gland Pharm
#zoledronic #injection #breakingnews #INS
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GLAND PHARMA RECEIVES USFDA NOD FOR ZOLEDRONIC ACID INJECTION
Link: https://t.co/jXu7fuSZLO | News: Gland Pharm
#zoledronic #injection #breakingnews #INS
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Although #bisphosphonates are used to treat acute #osteonecrosis, reducing pain and helping to prevent disease progression and #bone collapse, long term use of bisphosphonates has also been associated with the development of osteonecrosis in sites other than the jaw. #Zoledronic acid is associated with a higher risk of osteonecrosis than less potent bisphosphonates, and this risk gradually decreases after the end of therapy, however, it is still increased >5 years later. Treatment with #denosumab is also associated with an increased risk of osteonecrosis.
*Nordström, P., Bergman, J., Ballin, M., Björk, S. and Nordström, A. (2020), Bone-Specific Drugs and Osteonecrosis of Sites Other Than the Jaw: A Nationwide Cohort Study. J Bone Miner Res, 35: 1703-1710.
🔗https://t.co/QGJ1E35VCo
IV #bisphosphonates (i.e. #zoledronic acid, #pamidronate) are used in the treatment of #hypercalcaemia of malignancy in adults, however, the current evidence and guidelines suggest using #denosumab in preference to IV bisphosphonates as first-line pharmacological treatment in these cases:
◦ Although comparative studies of IV bisphosphonates and denosumab did not report treatment of hypercalcaemia of malignancy as an endpoint, the results of indicate that denosumab is a more potent suppressor of bone turnover and, therefore, is expected to be more effective.
◦ Side-effect such as infusion reactions and renal injuries are also more common with IV bisphosphonates than with denosumab.
◦ Denosumab has additional advantages in that it can be administered subcutaneously in community settings and can be used in stage 4+5 CKD, albeit with a higher risk of #hypocalcaemia.
*Mc Donald D, Drake MT, Crowley RK. Treatment of hypercalcaemia of malignancy in adults. Clin Med (Lond). 2023 Sep;23(5):503-507.
🔗https://t.co/dFYn6mVQwA
Biphosphonates may help managing hypercalcemia in metastatic breast, prostate cancer and multiple myeloma ⚠️⚠️
What is the role of #Zoledronic acid (ZA) in neovascular age-related #macular degeneration? A pilot randomized control trial shows ZA may improve vision (+8 letters BCVA vs placebo) when added to anti-VEGF therapy: https://t.co/F2V4tvQdFM.
#nAMD #Ophthalmology #Retina #Optometry #Vision #Eyehealth
A new #JBMR study of hip fracture patients who were treated with #zoledronic acid administered during initial fracture hospitalization revealed significantly reduced rates of all-cause mortality relative to comparison subjects @OUPMedicine
Read more here: https://t.co/Twf48EKBRX
What is better for #Rx of
#osteoporosis?
#Denosumab or ##Zoledronic acid?
#Prolia compared to #Aclasta
Giant admin US data of 125,000 Rx niaive women with #OP
▶️Prolia has LESS fractures!
POS0583 #EULAR2024 @eular_org @RheumNow
#Denosumab🆚#Zoledronic Acid in #osteoporosis
Denosumab reduced
▶️Major osteoporotic risk by 26%
▶️Hip by 34%
▶️Nonvertebral by 33%
▶️Non-hip, nonvertebral by 31%
▶️Hospitalized vertebral #fractures by 10%
#ACR23 Abstr 2529
👉🏽https://t.co/Qc95QFkLQE
Thank you to #KatieAndTheTeam at the #MacmillanUnit at @MidCheshireNHS I was treated like a Queen #Zoledronic x1 ✅ 5 more to go #checkYourBoobs #breastcanceradventure
😊Pleasure to share the excellent article: #Multiplexed #bioluminescence imaging of #cancer cell response to #hypoxia and #inflammation in the caudal-artery #injection model of #bone #metastasis during #zoledronic acid #treatment.
#MedEd #CancerMetastasis #CancerResearch
🧐What are the latest research findings in the field of #bone #metastasis?
Key words:
1⃣bone metastasis
2⃣multiplexed bioluminescence imaging
3⃣zoledronic acid
🔗PDF: https://t.co/4JYdtnWqaL
#Zoledronic acid associated with #atrial #fibrillation in global adverse #drug #reaction database https://t.co/rpTqdxLAn9 Evidence against cardio-protection by #bisphosphonates. Is reaction clouded by flu-like symptoms post-injection?
When #cancer spreads to the #bone, it can cause pain, fractures, and other problems.
Study Explores Jaw Problem Linked to #Zoledronic Acid, Finds #Risk Factors.
National Cancer Institute (NCI) JAMA Oncology Mayo Clinic https://t.co/lHNDPqvLYQ
#Denosumab and #ZA may be as effective as #teriparatide for #hipfracture #prevention in #frailolderadults.
Given their #lowercost and easier administration, denosumab and #Zoledronic are likely preferable nonoral treatments for most frail, #olderadults.
https://t.co/Wa7GOYcXyj
From Issue 6: "#Zoledronic Acid Versus #Denosumab for Prevention of Spinal Cord #Compression in Advanced Cancers With #Spine #Metastasis: A Meta-Analysis of Randomized Controlled Trials"
https://t.co/o9hXpEMADa
#spinalcord #spinalcancer #oncology #spinecare #spinaldisorders
Fractured tooth #Zoledronic Acid Zometa treatment=high risk Osteonecrosis of jaw (ONJ) one most relevant & specific complication of biphosphonates.
#shielding need a specialist
UDC in my area
GP No calls to after 10am
@WestminsterConnect has no info
111 on 3rd triage Call
#Carbon-Ion Beam Irradiation Alone or in Combination with #Zoledronic acid Effectively Kills #Osteosarcoma Cells
by Eun Ho Kim, Mi-Sook Kim et al.
👉https://t.co/CmE80acRRm
#carbonion
#ZOL
#OSA
#bonecancer
@VincentRK @guptaarjun90 @MartyMakary @HopkinsMedicine @oncology_bg @JAMAOnc Thankfully, I sat next to @MorieGertz during session so I did not falsely believe that #denosumab was superior to #zoledronic acid.
https://t.co/E2hDB6Gz0D
Long-term use of #alendronate and #zoledronic acid for more than three years reduces the rate of vertebral fracture in treatment-naive postmenopausal #women with notable, yet rare, adverse events. #MDedge https://t.co/jI5f6qxHnE
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