Top Tweets for #acml
#ASCO26 #MDS_MPN #aCML #CNL #leusm
Dr. Kuykendall: Phase 2 study of fedratinib in MDS/MPN overlap neoplasms and chronic neutrophilic leukemia (n=25) demonstrated meaningful clinical activity in a difficult-to-treat population.
πΉ Diagnoses: aCML, CNL, MDS/MPN-U, MDS/MPN-RS-T
πΉ Median age 69 years; 76% harbored β₯3 mutations, ASXL1 in 56%, splicing mutations in 76%
πΉ Fedratinib 400 mg daily
Key efficacy:
β
Spleen response rate: 30% (6/20 evaluable)
β
Mean spleen volume reduction: 30%
β
Symptom response rate: 47% (9/19 evaluable)
β
Mean TSS improvement: 41% at 24 weeks
Takeaway: Fedratinib produced consistent reductions in splenomegaly and symptom burden across MDS/MPN overlap syndromes and CNL, supporting JAK2 inhibition as a therapeutic strategy beyond classical myelofibrosis. Larger studies will be needed to better define disease-specific activity, hematologic responses, and durability of benefit.
#ASCO26 #MPNsm #MDSMPN #aCML #CNL #Leuem #JAKinhibitors
Abdul Mannan Inside the Diagnostic Maze of Atypical CML
https://t.co/3lrfcnUbTs
#ACML #AtypicalCML #Medicine #Hemostasis #CML #AtypicalChronicMyeloidLeukemia #Thrombosis #HemostasisToday #ChronicMyeloidLeukemia #MedX #MedEd #Health #Hematology
Words of wisdom about fatherhood.
#ACML #Karine #Deltarune #Brockneslon #Egypt #congratulationGus #WednesdayMotivation #lutnick #usatoday #Boisson #NationalCheeseDay #dukedennis
The diamond hands in this group are whatβs gonna make it!
#ACML
#ETH #Ethereum #LaCasaDeLosFamososCol2 #Beckysangels #SB19 #4EVE
β‘οΈ π‘π²π ππ
π½πΏπ²ππ ππΆπππΆπ»π΄!
π₯ Entered Trending | @abraxasethereum
Abraxas Capital...Limited | #ACML
https://t.co/E8jYaMfW7G
π LIQ: $60.08K | MC: $411.5K
#ETH #Crypto #Bitcoin
β‘οΈ π‘π²π ππ
π½πΏπ²ππ ππΆπππΆπ»π΄!
π₯ Entered Trending | @abraxasethereum
Abraxas Capital...Limited | #ACML
https://t.co/E8jYaMfW7G
π LIQ: $60.08K | MC: $411.5K
#ETH #Crypto #Bitcoin
π #CoreChain meme king #AMCL is redefining crypto with AI! π‘ The future is hereβare you ready?
#CORE #AMCL #AI #CryptoRevolution
Our DMPS paper has won the 16th Asian Conference on Machine Learning #ACML Best Paper Runner-Up ward! Many thanks to the ACML 2024 conference committee.
DMPS https://t.co/QwraBUhq26 got accepted by ACML2024, where we proposed a simple and fast method to approximate the likelihood score for solving inverse problems using diffusion models. Moreover, a unified approach for both diffusion and flow-based models is illustrated.
Excited to announce our upcoming tutorials and workshop about #Causal #Agent & #LLM.
π #AAAI2025 #AAAI Workshop on Artificial Intelligence with Causal Techniques.
π#ACML2024 #ICDM2024 (full-day) tutorials on Causality and Large Models! π· π·
π‘π
#ACML tutorial details: https://t.co/JfZNObJATd.
Stay tuned for details on #ICDM and #AAAI!
Great conference. Cannot AC this year because am general chair for #ACML, Asian #MachineLearning , running when ICLR ACs do their work.
Announcing the ICLR 2025 Call for Papers!
Abstract submission: 11:59pm, Sept 27 (AoE)
Submission date: 11:59pm, Oct 1 (AoE)
Reviews released: Nov 12
Author/Reviewer Discussion: Nov 12-26
Author Last Day to Reply: Nov 27
Final Decisions: Jan 22 2025
https://t.co/SEaF7f01dP
Large study of #aCML or #MDS_MPN_N
ππ» mutations found 50%
ππ» +8 most frequent
ππ» SETBP1/CSF3R
ππ» HCT β¬οΈ OS
β¦@BloodAdvancesβ©
Characteristics, primary treatment, and survival of MDS/MPN with neutrophilia: a population-based study https://t.co/aeKh4PLCjX
Differences between #CNL and #aCML. Largest study for survival from #NCDP
Check the other study about molecular differences comments ππΌ
@BloodAdvances
CNL and aCML are prognostically distinct: a large National Cancer Database analysis https://t.co/zlTVvh7HCt
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