Top Tweets for #apol1
📣 New publication in @FrontiersIn - Nephrology 📖
We are pleased to share our new work:
'Beyond the test: patient-reported concerns and worries regarding kidney conditions and #APOL1 genetic testing among Black patients'
🧬Among 200 Black adults in the #StLouis APOL1 cohort study with completed 3-month follow-up, 17.5% had an APOL1 high-risk genotype (2 risk variants).
🔵 At baseline, concerns about kidney conditions were substantial, with 39% of participants reporting being extremely concerned. At 3 months, concern remained unchanged in 45%, decreased in 36%, and increased in 19%.
🔵 APOL1 high-risk genotypes were more common among participants whose kidney concerns increased compared with those whose concerns decreased (29% vs 11%; P = 0.02).
🔵 Worry specifically related to having an APOL1 high-risk genotype declined from 14% at baseline to 8% at 3 months.
These findings highlight the importance of understanding the patient experience alongside genetic risk and of developing patient-centered education, communication, and counseling around APOL1 genetic testing.
🤝🏽 We are deeply grateful to the participants who shared their experiences and made this work possible, ➕ to our dedicated co-authors: @renginels | Bryan Clair | @AlizaAnwarMemo1 | John Edwards | @KanaHelloKidney | @Barisafsar75 | Mark Schnitzler | Huiling Xiao | Amber Carriker | Fadee Abu Al Rub | Chi-yuan Hsu | Anthony Muiru | Barry Freedman | Marie Philipneri | @yasar_caliskan
🌟 We also thank the St. Louis APOL1 Study Collaborators for their partnership: Orhun Aydin | Ezequiel Bellorin Font | @AvaDelonai6124 | @HoujeijNourhan | Kevin Lee | @nephrom | @drrushdafaruk | Marilyn Maxwell | Mowaffaq Said | @Farzana_HoqueMD | Amy Mosman | Anne Buganski | Mary Lesko | Kenan Li| Enbal Shacham | @MaiVoMD
We are especially grateful to Mid-America Transplant for invaluable support ➕commitment to our shared #StLouis kidney #community. 💙💚
🏥 @SSMHealthSTL | @SSMHealth | @slusom | #MidAmericaTransplant | @UCSF | @WakeForest
We look forward to continuing to connect with our community around kidney health, transplantation, research, and education at upcoming events—including the Celebrate Life Walk, PKD Walk and ASN Kidney Week
💫 #Nephrology #APOL1 #KidneyDisease #GeneticTesting #Genomics #PatientCentered #KidneyHealth #ClinicalResearch 🧬
📖 Read the full open-access article and learn more about what patients report about kidney health and APOL1 genetic testing: https://t.co/lLiGdK43bl
📣 Proud to share this important new video resource from the @ApolloNetwork13 (#APOL1 Long-term Kidney Transplantation Outcomes Network🧬 ) Community👇🏽
How can we advance research involving deceased donor organs while ensuring that donor families are informed, respected, and meaningfully engaged? 💛
🎥 In this conversation, donor family members, #CommunityAdvisors, researchers, and #transplantprofessionals come together to discuss best practices for next-of-kin #research authorization after consent for organ donation, and why these conversations matter.
🧬 We also introduce the NIH-funded #APOLLOStudyand discuss how understanding APOL1 genetic variants in kidney donors and recipients may help improve #KidneyTransplantationand advance health outcomes in African American communities. 💙💚
🙏🏽 Very grateful to the @AST_info (#AST) for its partnership with the APOLLO #DisseminationWorkingGroup in bringing this important community conversation forward. 💙💚
🤝🏽 Kudos to our outstanding panel and community partners: @itsglendar | Jennifer Davis | @DrRoSchmidt | @nicholejeff | @KristaLentine | @Heather Johnson | Marva Moxey-Mims | @jnkodim | Mariella Ortigosa-Goggins ➕ the dedicated working group for developing this series @anna_smith_anna | @SuperChaperone | @sylviaerosas | @lrussell6868 | @Kashawna__ 💫
🫶 #Research is strongest when the communities it is intended to serve have a voice in how it is designed, discussed, and carried forward. 🦋
#APOLLO #APOL1 #KidneyTransplant #OrganDonation #TransplantResearch #CommunityEngagement #KidneyHealth #HealthEquity #Transplantation #AST
📺 Watch and share the conversation: https://t.co/inT6bsAJHA
In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification. https://t.co/GsGIDAe419
#APOL1 and chronic kidney disease in pediatrics: a study from the Biorepository and Integrative Genomics Initiative @ped_neph
#openaccess
https://t.co/SohmsDm9js
#APOL1 Variants, #AKI, and P#rogression to Kidney Failure in People of African Ancestry Living with #HIV
#VisualAbstract by @hellokidneyMD
https://t.co/MHHdMxtf0u
@rachhung
In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification.
https://t.co/QTFA4EM0A0
In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification.
https://t.co/rt1iMAxY2G
In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification.
https://t.co/gtfuj6eDka
📣 Hot off the press (June 22)! 📖
🤲🏽 Honored to share the publication of findings from the ‘#LivingDonorExtended Time Outcomes’ (#LETO) Study, an ancillary study of the ‘#APOL1 Long-term Kidney Transplantation Outcomes’ (#APOLLO) Network Study:
“#Apolipoprotein L1 Gene Genotype and Kidney Outcomes After #LivingKidneyDonation”
🧬 Key finding: APOL1 genotype is a significant risk factor for reduced kidney function following living kidney donation. These results support #APOL1Genotyping for Black living kidney donor candidates in the U.S. to improve risk stratification and informed decision-making.
📄 Read the @JAMAInternalMed article:
https://t.co/RJoYe6IiK0
🎤 If you’re attending the @ATCMeeting (#ATC) 2026, please join us for presentations on LETO:
• June 23, 9:00 AM — Abstract 921, Plenary Session | Ballroom
• June 23, 10:09 AM — Abstract 938 | Room 253A
🙏🏽We are grateful to the @NIDDKgov for funding this work and to our outstanding collaborators: Chi-yuan Hsu, Ying Gao, Barry I. Freedman, @MitchellLunn , Anthony Muiru, Mark Schnitzler, Jasmin Divers, @mannonmom, Nicholette Palmer, Amy Karger, @KristaLentine *, and @emp802* | @UCSFTransplant | @slunephrons | @SSMHealthSTL | @slusom |
@wakeforestmed | @NebraskaMed | @nyuniversity 🫶🏼
🤝🏽 We look forward to the discussion and to advancing our understanding of #genetic tools that can help improve the safety and long-term outcomes of living kidney donation.🧬
💙💚 #KidneyDonation #Transplantation #LivingDonation #PrecisionMedicine #Genetics #APOL1 #APOLLOStudy #LETO #ClinicalResearch #ATC2026 🦋
In a national cohort, Black living kidney donors with #APOL1 high-risk genotypes had more than twice the risk of reduced kidney function nearly 20 years after donation, supporting genotyping for better risk stratification.
https://t.co/Wftltzjq56
When should APOL1 genetic testing be considered and how should results be shared with patients and families? Listen for practical insights.
Supported by Vertex Pharmaceuticals.
🎧 https://t.co/RGuDW0NrDB (Episode 050)
#APOL1 #Genetics #CKD #Nephrology
Wonderful to see State Representative Lauren Ashley Simmons at the Sunnyside center health fair. We screened over 50 high risk patients for Apol1 #Apol1, #Sanofi, #BoehringerIngelheim
💫 As the @ATCMeeting (ATC) 2026 approaches, I am reflecting on the #WorldTransplantCongress2025 – including our session on ‘Ancestry-Specific Variation in the #ApolipoproteinL1 Gene (#APOL1) and #KidneyTransplant Outcomes’.
🎤 It was a privilege to join colleagues from across the transplant community to discuss the rapidly evolving science of APOL1 genetics and its implications for kidney transplantation. My presentation, ‘Exploring Solutions to Ethical Challenges of APOL1 Testing,’ was part of a broader conversation about how advances in genomics can inform donor evaluation, patient counseling, and clinical decision-making. 🤝🏽
The field continues to move forward, and we are excited to share new work at ATC 2026:
🌟 ‘Outcomes After #LivingKidneyDonation by Race and APOL1 Genotype: Results from the #LivingDonorExtendedTimeOutcomes (#LETO) Study’
🌟’Impact of Donor APOL1 Genotype on 15-Year Living Donor Kidney Transplant Graft and Patient Outcomes: Results from the Living Donor Extended Time (LETO) Study' (plenary)
🧬 We look forward to sharing progress in understanding the long-term impact of donor genetics on transplant outcomes. As #transplantation enters an era of precision medicine, studies such as LETO are helping to define how genomic information can be used to better understand risk, personalize care, and support informed decision-making for donors and recipients alike.
🤝🏽 Our team looks forward to engaging discussions with wonderful colleagues at ATC 2026 and to the continued advancement of genetics-driven approaches in transplantation. 💙💚 #Colleagues @CunningBeans | @MichelleJTx
💫 #ATC2026 #TransplantScience #TransplantResearch #KidneyTransplantation #LivingDonation #APOL1 #Genomics #PrecisionMedicine #ClinicalResearch | #Community | @SSMHealthSTL | @SSMHealth 🏥
📣 📖 Proud to share our latest publication in Frontiers-Medicine #Nephrology:
🧬’ #ApolipoproteinL1 (#APOL1) genetic testing, family history of hypertension, and kidney disease in a Midwestern U.S. cohort’
This study examined the intersection of #APOL1genetic risk, family history, and kidney health among Black adults participating in the #StLouisAPOL1 cohort study.
🔹 Among 220 participants who underwent APOL1 genotyping, we found that APOL1 high-risk genotypes were more common among individuals with a family history of hypertension and/or kidney disease, greater antihypertensive medication burden, lower kidney function, albuminuria, and early decline in eGFR.
🔹 Importantly, the findings highlight that genetic risk and family history provide overlapping—but not identical—information about kidney disease susceptibility. Together, these observations reinforce the need for integrated approaches that combine genetics, clinical assessment, and family history to improve kidney disease risk stratification and early identification of individuals at increased risk.
🌟 What makes this publication especially meaningful is the extraordinary collaboration behind it.
This work brought together investigators from SSM Health Saint Louis University Hospital, Saint Louis University School of Medicine, Mid-America Transplant, UCSF Department of Medicine, Wake Forest University, and the multidisciplinary #StLouisAPOL1StudyCollaborators. The project reflects the collective efforts of nephrologists, genetic researchers, epidemiologists, biostatisticians, research nurses, and community partners committed to advancing kidney health equity.
🖋️Authors include: @renginels | @AlizaAnwarMemo1 | @KanaHelloKidney | @Barisafsar75 | @AmberCarriker | @AbualrubFadee | @yasar_caliskan | @SSMHealthSTL | @SSMHealth | @UCSFNephrology | @wakeforestmed | @slusom
🤝🏽 St. Louis APOL1 Study Collaborators include: @AvaDelonai6124 | @HoujeijNourhan | @nephrom | @drrushdafaruk | @MowaffaqSaid
🙏🏽We are grateful for the support of #MidAmericaTransplant, whose commitment to innovation, research, and collaboration continues to advance understanding of kidney disease risk and opportunities for prevention.📊
This study represents another important step toward understanding how genetic and familial factors can be incorporated into more precise, patient-centered approaches to kidney disease prevention and care.
📖 🆓 Open Access:
https://t.co/nEC2AyF5UD
🧬#APOL1 #KidneyDisease #Nephrology #Genetics #PrecisionMedicine #ChronicKidneyDisease #KidneyHealth #ResearchCollaboration #Multidisciplinary #PublicHealth #FrontiersInNephrology 🩺
Learn about APOL1-mediated kidney disease (#AMKD), including symptoms, genetic risk factors, diagnosis, treatment options, and emerging research shaping the future of personalized kidney care: https://t.co/M6adxjhIw9
#KidneyHealth #RareDisease #APOL1 #RareKidney #KidneyWarrior
Genetics, environment, and kidney disease progression are closely connected. This episode helps unpack those relationships.
🎧 https://t.co/RGuDW0NrDB (Episode 050)
Supported by Vertex Pharmaceuticals.
#Genetics #APOL1 #KidneyCare
🚨Today is APOL1‑Mediated #Kidney Disease Day & Sharron Rouse (@Srouse815 @KKidneys) reminds us why her story can’t wait.
It moves from sudden swelling to #dialysis, #transplant & finally the clarity of learning her #APOL1 status👉️https://t.co/gxqz41VIln
#AMKD #NephTwitter
Nine-protein #APOL1 #ProteomicRiskScore (#APRS) predicting composite outcome of ≥40% #eGFRdecline, #KidneyFailure or death to bridge gap between #GeneticSusceptibility & clinical translation https://t.co/SVK1XjQEpJ @KSusztak #TranslationalScience
Gran sesión del Dr. Shabaka sobre el papel de los alelos de riesgo en #APOL1🧬y mutaciones en #COL4🧬como modificadores genéticos en las #enfermedadesglomerulares
📍Entender la genética es clave para interpretar muchos casos “atípicos”.
#GLOSEN #GlomerularDiseases
Last Seen Hashtags on Sotwe
TWERK
Seen from Germany
oilsex
Seen from India
مقوم
Seen from France
globaldelay
Seen from United States
bator
Seen from Turkey
minichat(********)******* +filter:native_video
Seen from United Kingdom
brosis
snapchat(***)(*)(***) +filter:videos
Seen from United Kingdom
马眼开发
Seen from Norway
fiorde
Seen from Italy
Trends for you
Most Popular Users
Elon Musk 
@elonmusk
241.5M followers
Barack Obama
@barackobama
118.9M followers
Cristiano Ronaldo
@cristiano
114.6M followers
Donald J. Trump
@realdonaldtrump
111.8M followers
Narendra Modi
@narendramodi
107.1M followers
Rihanna
@rihanna
98.7M followers
NASA
@nasa
92.3M followers
Justin Bieber
@justinbieber
91.8M followers
KATY PERRY
@katyperry
90.1M followers
Taylor Swift
@taylorswift13
84M followers
Lady Gaga
@ladygaga
75.5M followers
Virat Kohli
@imvkohli
73.5M followers
Kim Kardashian
@kimkardashian
70.9M followers
YouTube
@youtube
68.8M followers
Neymar Jr
@neymarjr
66.6M followers
Bill Gates
@billgates
65.3M followers
Selena Gomez
@selenagomez
63.1M followers
The Ellen Show
@theellenshow
62.2M followers
CNN
@cnn
61.7M followers
X
@x
60.7M followers