Top Tweets for #ardd
Aging is pleased to announce that we are a media partner of the 13th Aging Research & Drug Discovery Meeting (ARDD), taking place October 1–3 at Harvard University in Boston, MA.
🔗 Learn more:
https://t.co/SEXG7coU0w
#Aging #ARDD #Research #DrugDiscovery #Longevity #Harvard
Registration for #ARDD 2026 is now open.
Explore the program for the 13th Aging Research and Drug Discovery Meeting and secure your place at https://t.co/8Zyg87R5jA
Aging is pleased to announce that we are a media partner of the 13th Aging Research & Drug Discovery Meeting (ARDD), taking place October 1–3 at Harvard University in Boston, MA.
🔗 Learn more:
https://t.co/SEXG7coU0w
#Aging #ARDD #Research #DrugDiscovery #Longevity #Harvard
ARDD, Fisheries, SC Welfare Minister Sudhangshu Das At The Review Meeting Of Three Departments Thousands Of Rural Families Have Found Self-Reliance Through Various Government Projects.
#ARDD #Fisheries #SC #Sudhangshu #Das #Review #Meeting #Various #Government #Projects
finally, #ardd conference has released the video covering my talk at their #Gerophysics session (the link is in the first comment, please like and repost - thank you!). As you may know, we frame aging through thermodynamics and the second law — viewing the body as a heat engine where metabolism inevitably produces "entropic damage" (irreversible, uncorrelated molecular-level insults like random DNA mutilations or chemical errors). This damage accumulates roughly linearly with time.
While physiological markers (e.g., recovery speed, variance in biomarkers, clinical aging clocks) often decline linearly or subexponentially, mortality increases exponentially (Gompertz law). We explain this discrepancy: linear entropic damage slowly erodes the "stability" of regulatory networks (the "free energy landscape" governing biological control), making the system increasingly sensitive to fluctuations ("noise").
Key Concepts Introduced:
* Entropic damage — irreversible, Poisson-like accumulation of uncorrelated errors (visible as a linear component in PCA of molecular/physiological data).
* Dynamic / correlated response — the body's pathways react in a correlated, exponential/hyperbolic way to stress (reversible component, e.g., improved by parabiosis in mice/dogs, but entropic damage itself is not reversed).
* Noise / fluctuations — unpredictable stress or variability (not chronic predictable stressors like smoking); this noise widens the gap between average and maximum lifespan. Low-noise individuals/animals show steeper mortality curves.
* Thermodynamic fidelity — how efficiently metabolism avoids creating damage (linked to metabolic rate and barrier heights in regulatory networks).
* Extreme statistics — aging drift is dominated by rare, large failures (Gumbel distribution), so small linear erosion of barriers → exponential mortality rise.
* Effective temperature — higher effective temperature (more noise/entropy production) accelerates instability.
Data Highlights:
* PCA on human/mouse/dog single-cell/multi-omics data shows two main aging signatures: linear (entropic/red) vs. exponential (dynamic/green).
* Parabiosis experiments reverse the dynamic signature but leave entropic damage untouched.
* Dog lifespan data: breeds with lower noise show higher Gompertz exponents (faster acceleration of mortality).
* Human max lifespan (~120 years) reflects the ultimate stability limit set by network topology and noise control, not just average damage levels.
Implications for Interventions:
* Targeting average biomarker levels (inflammation, etc.) has limited effect.
* Bigger gains likely from reducing noise/fluctuations since this may bridge the mean and the maximum lifespan in our species.
* Calls for "level-3" interventions that address these deeper control layers.
please help by pushing the like and repost buttons!
One of the best resources in our field — https://t.co/nnMXjYkSZ3 🧬
And now they’ve mentioned us there 😊
https://t.co/maACXLcvvl
Chatted with founder Reason at #ARDD about his biohacking experience.
#unlimitedbio
✨ And of course, it was a joy to see both new & familiar faces 💜
#longevity #ardd #ardd2025 #Copenhagen #UnlimitedBio
Jeroen Aerssens, PhD, presented updates on RJx-01, our Phase 2 asset for sarcopenia and highlighted human MoA data showing RJx-01’s capability to improve mitochondrial energy production and to reduce inflammation and collagen deposition. Proud sponsor.
#AgingResearch #ARDD
Longevity Biotech @lifebiosciences presents new data at #ARDD on Partial Epigenetic Reprogramming Platform in preclinical studies:
🐭ER-300 improved liver health biomarkers in MASH mice
🐒ER-100 restored methylation patterns & promoted neuronal regeneration in NAION primates
Join Managing Partner Tom Zuber at the 12th @ARDD_Meeting at the University of Copenhagen, moderating the "Investor Panel-Early Stage" and the "Investor Panel-Growth Stage" on August 27th.
#ARDD2025 #ARDD #UniversityofCopenhagen #Longevity #ZuberLawler
So happy to be at ARDD! 💜
Captured moments: loved discussing scientific challenges with Reason (https://t.co/nnMXjYkl9v), and, of course, my special joy - taking pictures with genetically modified humans (hTERT IV 😉).
#ARDD #Copenhagen #longevity #biotech
🌍 The countdown is on for the 12th Aging Research & Drug Discovery Meeting (#ARDD 2025), taking place August 25–27 in Copenhagen!
Insilico Medicine a proud sponsor contributing to this premier event advancing the science of healthy #longevity. Don’t miss our featured talks:
🎤 August 27, 19:20–19:40
From Disease to Discovery: Leveraging IPF Aging Biology for Novel Therapeutic Targets
Fedor Galkin, PhD
🎤 August 29, 19:00–19:20
Discovery and Development of Longevity Therapeutics: When Should We See the First Rationally-designed Geroprotectors with the Clinical Longevity Protocol?
Alex Zhavoronkov, PhD
🔗 Learn more & register for the virtual pass today: [https://t.co/K158Gzr8gP]
#ARDD2025 #AgingResearch #DrugDiscovery #Longevity #AI #InsilicoMedicine
![InSilicoMeds's tweet photo. 🌍 The countdown is on for the 12th Aging Research & Drug Discovery Meeting (#ARDD 2025), taking place August 25–27 in Copenhagen!
Insilico Medicine a proud sponsor contributing to this premier event advancing the science of healthy #longevity. Don’t miss our featured talks:
🎤 August 27, 19:20–19:40
From Disease to Discovery: Leveraging IPF Aging Biology for Novel Therapeutic Targets
Fedor Galkin, PhD
🎤 August 29, 19:00–19:20
Discovery and Development of Longevity Therapeutics: When Should We See the First Rationally-designed Geroprotectors with the Clinical Longevity Protocol?
Alex Zhavoronkov, PhD
🔗 Learn more & register for the virtual pass today: [https://t.co/K158Gzr8gP]
#ARDD2025 #AgingResearch #DrugDiscovery #Longevity #AI #InsilicoMedicine](https://pbs.twimg.com/media/Gy5RwICXUAAZRhm.png)
Dear friends, The deadline is approaching to apply for the pitch session at ARDD. If you are a startup #ARDD may be the place for you to pitch. Your pitch will be broadcast to 6K people watching online and there will be 40+ VCs at the meeting. Please spread the word! 🙏🙏
Thanks, all, for the great meeting and the great article to write together! We started an aging project!
#ARDD
@ARDD_Meeting
https://t.co/ZsmmYSc8yC
Our #ARDD talk about life models is finally out!
Watch it on YT and follow @ARDD_Meeting for even more exciting longevity talks
Insilico Medicine with #ARDD
Frank Pun and Fedor Galkin at ARDD2024: Dual-Purpose Target Discovery and Aging Research with PreciousGPT Models
https://t.co/X2g2RpPI9v
Insilico Medicine with #ARDD
Frank Pun and Fedor Galkin at ARDD2024: Dual-Purpose Target Discovery and Aging Research with PreciousGPT Models
https://t.co/X2g2RpPI9v
NaNotics LLC with #ARDD
Louis Hawthorne at ARDD2024: NaNots: A Novel Platform for Adsorbing Soluble Drivers of Diseases & Aging
https://t.co/O0VUVPXphS
Timeline with #ARDD
Chris Rinsch at ARDD2024: The Impact of the Postbiotic Urolithin A (Mitopure) on Health and Longevity
https://t.co/uTc7jMjW1x
ACCELERATED BIOSCIENCES CORP. with #ARDD
Yuta Lee at ARDD2024: Trophoblast Stem Cell Secretome for Cell Senescence
https://t.co/hkhQUYYoWw
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