Top Tweets for #assembloid
Indeed, a spectacular image of an #assembloid
Image of the kidney assembloids featured among @Nature best science images of 2025: https://t.co/R9Rhx7yCuw. It was a pleasure to collaborate with @LiLab_Kidney @Pmed27 @bohovyk on this work. See original ms at @CellStemCell: https://t.co/OYL9pX4v5t
In a recent with Jan Carette’s lab at Stanford University, we introduce an #assembloid model for studying neuro-infection with enteroviruses including poliovirus.
The videos below capture the loss of human muscle contraction, which is under the control of spinal cord neurons, after a week of infection.
Work led by Christine Peters, Jimena Andersen and Min-Yin Li
https://t.co/J2EZ7s02cn
Single rosette-based generation of uniform cortical assembloids recapitulating cellular interactions between neurons and glial cells
Our recent work published in Nature Communications!
#brain #brainorganoid #organoid #stemcell #assembloid
This week we introduced an #assembloid based platform to begin studying how #enteroviruses affect human neuromuscular systems.
These enteroviruses, which include including poliovirus, EV-D68 and EV-A71, are a leading cause of viral meningitis in children and have been linked to a polio-like paralysis, which makes understanding their cellular impact especially important.
In this @biorxivpreprint we show how polio and two other enteroviruses lead to loss of muscle contractions, and how this may relate to the distinct cell tropisms and kinetics of damage for each virus.
Collaboration with the Jan Carette lab here at Stanford.
Work led by Christine Peters, Jimena Andersen (now faculty at Emory) and Min-Yin Li.
Video shows timelapse imaging of infection of spinal organoids with each of the 3 viruses
We developed the assembly approach to generate positional specific skin organoid, and remarkably, amnioid which can grow up to centimeter size! #organoid #amnion #development #assembloid #mesoderm
Lateral plate mesoderm directs human amnion and ventral skin organoid formation https://t.co/xkYva33Oe5 #biorxiv_devbio
#UCLA researchers announced on September 11 a new stem cell-derived "#assembloid" model demonstrating how #SCN8A #gene variants (linked to #epilepsy) cause hyperactivity in the #cortex while disrupting #hippocampal rhythms. The work shows these disruptions may explain
Immune-Vascular Forebrain #Organoid #Assembloid to model the impacts of APOE genotype (ε2/2 vs 3/3 vs 4/4) on #SARSCOV2 infection
Isogenic #hiPSC-derived FOXG1+Nestin+ forebrain neural progenitor➡️ forebrain neuron + astrocyte + oligodendrocyte
hiPSC-derived yolk sac➡️ #EndothelialCell #Pericyte #Microglia
Matrigel-based assembly
Both APOE ε2/2 & ε4/4 assembloids are more susceptible, albeit with different inflammatory cascades
bioRxiv 2025
https://t.co/Shttre9lMG
📅 Date: Tuesday, June 3, 2025
🕘 Time: 09:30 AM EST
🌐 Link to register: https://t.co/Zc4gqNTmQG #Doric_Lenses #Doric_Webinar #VoluScan™ #organoid #assembloid #live_cell_imaging
Review | Evolving from organoid to assembloid with enhanced cellular interactions
https://t.co/vsN0sPhHSn
#organoid #assembloid
This week we welcome the 2025 class of students for our hands-on Stanford @BrOrganogenesis course.
With students joining from across the globe, this is our most international class yet—diving into cutting-edge neural #organoid and #assembloid methods, ready to bring them back to their home labs.
Huge thanks to the phenomenal organizers @RebeccaJLevyMD Merve Avar & Sabina Kanton, and the entire lab.
Drs. @GregScherrer25 and @Sergiu_P_Pasca collaborated to establish a human ascending somatosensory #assembloid from #hPSCs that integrates somatosensory, spinal, thalamic, and cortical #organoids to model the spinothalamic pathway. 🧠
@Nature | https://t.co/rIIsKXVEzo
Evolving from organoid to assembloid with enhanced cellular interactions 10.26599/CO.2025.9410010 This review explores the emerging field of #assembloid technology, which integrates multiple #organoids or cell types into self-organizing 3D systems.
Evolving from organoid to assembloid with enhanced cellular interactions
10.26599/CO.2025.9410010
This review explores the emerging field of #assembloid technology, which integrates multiple #organoids or cell types into self-organizing 3D systems.
Great lecture by @Sergiu_P_Pasca on #assembloid @UCLchildhealth @DBC_ICH time to generate more assembloid from GI systems… watch this space @GiobbeGiovanni
Heart #Assembloid Vascularization (+pericyte coverage) & Innervation
1⃣#hiPSC-derived epicardium-myocardium #Organoid + 2⃣Sympathetic neuron #Spheroid
Beautiful vascular network!
Can we further differentiate it into A-C-V microcirculatory unit?😁
@marianamvab bioRxiv 2025
https://t.co/YzGoF15f7a
Incredible new work from @KostinaAleksa, @aaguirrecano, & team at @MSUIQ! This functional, highly complex human heart #assembloid could shed new light on cardiac development & congenital heart defects, while also serving as a tool for high-throughput drug screening.
I am pleased to present the latest work from our lab, a human heart-macrophage assembloid model powered by self-organization that incorporates autologous cardiac embryonic macrophages into human pluripotent stem cell-derived heart organoids:
https://t.co/i5nzpdq6kc
Led by Benjamin Sharpe (@BSharpeNotFlat), members of the Underwood lab (@TimTheSurgeon) characterized co-culture tumor-derived #organoids and cancer-associated fibroblasts in matrix-embedded #assembloid models of esophageal adenocarcinoma.
👉 https://t.co/whngChkvCW
#Pericyte #TunnelingNanoTube
Pericyte-Astrocyte TNT ⏫by #OxygenGlucoseDeprivation
Pericyte-to-Astrocyte Mitochondria transfer occurs on dish (via TNT or direct contact) or in 3D #Assembloid (via TNT or not?🤔), likely⏬Astrocyte Apoptosis
#EndothelialCell does a similar job to Astrocyte
Cell Death Dis 2022 @cddpress
https://t.co/ZuWekzm3Zd
Combined #assembloid modeling and 3D whole-organ mapping captures the microanatomy and function of the human #fallopian tube | Science Advances https://t.co/gvSElmsf8d
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