Top Tweets for #flyclock
A @cornellchem team featuring @10feng @cristhechemist present cryo-EM structures of the Cry-Tim complex, integral to the circadian clock and light entrainment in flies:
https://t.co/n1iL7qzIAq
#flyclock
In @NeuroCellPress @gliaful and colleagues identify glial control of daily variations of sphingolipids whose disruption alters Drosophila circadian circuits, via protein aggregate formation and sleep loss #flyclock:
https://t.co/VJFaKLmPJG
Bioluminescent assays are a key method in #chronobiology; a challenge has always been using this in live organisms. Here, the Top lab develop a technique to measure the oscillation of distinct neuronal and peripheral clocks in live Drosophila #flyclock:
https://t.co/T8PUq7gJWU
Rescuing a cry-deficient #flyclock with cry from different mosquitos, the Holmes lab @UCIrvineSOM show species-specific functions transfer to the fly:
https://t.co/WSW3iXYcHr
Can food act as a time cue in flies? A new #ClockBites from
@SheebaVasu @Sheetal_Potdar @jncasr:
https://t.co/XjJePDrvzP
#flyclock
Diurnal sphingolipid metabolism is required for circadian behaviour and brain circuit remodeling in Drosophila #flyclock. Paper by the team of Thomas Clandinin @Stanford in @NeuroCellPress:
https://t.co/1YBK77L3p6
#ThrowbackThursday to 2001. McDonald & Rosbash are the first to systematically study #circadian gene expression in 🪰. (https://t.co/D2wpRDASPR) @CellCellPress #flyclock #clock
Dorsal #clock networks drive temperature preference #rhythms in Drosophila (https://t.co/dwCTEFtZ2o) @CellReports #flyclock #circadian

#ThrowbackThursday to 2003. Cyran et al. discover a second feedback loop involving vrille, Pdp1 and Clock in the molecular clockwork of the 🪰. @CellCellPress @justinblau01 #circadian #clock #flyclock (https://t.co/2Uy4kX3KWQ)

It's 2002. Nitabach, @justinblau01 & Holmes show that electrical firing is an integral part of the #flyclock. Silencing firing disrupts locomotor & molecular #clock #rhythms in darkness, but only impairs them in LD. (https://t.co/NqqRScLhOj) @CellCellPress #ThrowbackThursday

Grab a ☕️ and have bite of #clocks. @blalagsol gives us a minute of "#circadian gene expression in non-clock neurons in 🪰 and their role in #sleep".
(https://t.co/CnUSi7GW2S) #ClockBites @genevunige @n_nagoshi #flyclock @SfNtweets @ChronobioCanada @EbrsOfficial @ResearchSleep
#ThrowbackThursday to 1999. The Taghert lab showed that mutation of pdf gene or ablation of PDF neurons severely impaired behavioral #rhythms thus highlighting the key role of PDF in the 🪰 #clock. (https://t.co/fphtDtWX1J) #flyclock
#JBR The Neuropeptide PDF Is Crucial for Delaying the Phase of 🪰 Evening Neurons Under Long Zeitgeber Periods. (https://t.co/G0WrFiqyMJ) @Uni_WUE #flyclock #circadian #chronobiology

#circadian #rhythm of 🪰 emergence provided many of the key concepts of #chronobiology. This gating of emergence is achieved by controlling the timing of the final steps of metamorphosis. (https://t.co/DohzCuybZT) @PNASNews #flyclock
#ThrowbackThursday to 1995. Charlotte Helfrich-Förster discovered and characterized the role of PDF in the 🪰 #circadian #clock network. (https://t.co/T0eP9FkVre) @PNASNews
#flyclock @SfNtweets #neuroscience @Uni_WUE

In 1998, a pair of @CellCellPress papers from labs of Rosbash and Hall identified CLK and CYC, the positive regulators of 🪰 #circadian #clock, using forward genetic screens. #ThrowbackThursday
https://t.co/udH8n47a21 https://t.co/J4bJExRARB @AlladaSleep #flyclock

In 1998, the lab of Michael Young cloned DoubleTime (DBT), a key 🪰 #clock component related to mammalian casein kinase 1e, which is mutated in naturally occuring #circadian tau hamster. DBT phosphorylates PER.
#ThrowbackThursday @CellCellPress #flyclock
https://t.co/PtCifbj7NB
#ThrowbackThursday to 1998 double-header in @CellCellPress, where Nobel 🏆winners Rosbash & Hall with P. Emery, @stani_bmg, @DrSteveKay showed that cryptochrome (CRY) is #light-sensitive & #circadian component of the 🪰#flyclock.
https://t.co/wEnoyRr9fz
https://t.co/xSrOMy2h4A

#ThrowbackThursday to 1994, @amitaseh, Jeff Price, Bernice Man and Michael Young identify the #clock #gene tim (timeless) using a forward genetic screen in @ScienceMagazine .
#flyclock #TST
https://t.co/THlroTUOsG

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