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Thank you for participating in the #GUPath #GradingChallenge!
Summary of grading aspects covered:
#Prostate cancer
1 - Rosette-like spaces
3 - Solid cylinders
Papillary #urothelial carcinoma
2 - Borderline LG/HG
4 - Mixed LG & HG
#RCC
5 - Syncytial multinucleate giant cells
This week’s final posting of #GUPath #GradingChallenge cases (5 of 5)👇
Clear cell #RCC 6 cm. Is this WHO/ISUP grade 4?
Please take the poll in comment.
Again share your thoughts #GU tweeples and let’s see the votes.
Case courtesy of @slusagar (Thank you!)
3 of 3. As shown there are 2 scenarios of “borderline” PUC:
1 - Morphology gray between LG & HG (so called LG/G2 vs HG/G2)
2 - Mixed LG & HG
#GradingChallenge
Case 2 - example of 1
Case 4 - example of 2
Thank you #GUPath tweeples! Last case (RCC) to follow!
3 of 3. As shown there are 2 scenarios of “borderline” PUC:
1 - Morphology gray between LG & HG (so called LG/G2 vs HG/G2)
2 - Mixed LG & HG
#GradingChallenge
Case 2 - example of 1
Case 4 - example of 2
Thank you #GUPath tweeples! Last case (RCC) to follow!
This week’s 4th posting of #GUPath #GradingChallenge cases (4 of 5)👇
Papillary #urothelial carcinoma, non-invasive. How will you report the grade? (2016 WHO)
Please take the poll in comment.
Again share your thoughts #GU tweeples and will see the votes.
Final poll: GP4 by 68% of 191 votes
I thought this example highlights issue about solid cylinders or thick cords for GP5. This descriptors need further elaboration.
Thanks #GUPath tweeples for voting!
Next is a controversial Urothelial carcinoma #GradingChallenge scenario!
This week’s 3rd posting of #GUPath #GradingChallenge cases (3 of 5)👇
#Prostate carcinoma. Is this Gleason pattern 4 or 5? Or if you think it’s mixed, what’s the predominant pattern?
Please take the poll in comment
Again share your thoughts #GU tweeples and will see the votes
This week’s 3rd posting of #GUPath #GradingChallenge cases (3 of 5)👇
#Prostate carcinoma. Is this Gleason pattern 4 or 5? Or if you think it’s mixed, what’s the predominant pattern?
Please take the poll in comment
Again share your thoughts #GU tweeples and will see the votes
Final: HG by 63% of 244 votes
Notable comments:
-Largest cells looks degenerative
-Background favored as HG
-1973 WHO may add info to borderline (HG/G2)
-Communication key
-Risk stratifiers have other variables
Great discussion! More #GUPath #GradingChallenge cases to follow!
This week’s 2nd posting of #GUPath #GradingChallenge cases (2 of 5)👇
Papillary #urothelial carcinoma, non-invasive. How will you report the grade? (2016 WHO)
Please take the poll in comment.
Again share your thoughts #GU tweeples and will see the votes.
Final: HG by 63% of 244 votes
Notable comments:
-Largest cells looks degenerative
-Background favored as HG
-1973 WHO may add info to borderline (HG/G2)
-Communication key
-Risk stratifiers have other variables
Great discussion! More #GUPath #GradingChallenge cases to follow!
This week’s 2nd posting of #GUPath #GradingChallenge cases (2 of 5)👇
Papillary #urothelial carcinoma, non-invasive. How will you report the grade? (2016 WHO)
Please take the poll in comment.
Again share your thoughts #GU tweeples and will see the votes.
This week’s 2nd posting of #GUPath #GradingChallenge cases (2 of 5)👇
Papillary #urothelial carcinoma, non-invasive. How will you report the grade? (2016 WHO)
Please take the poll in comment.
Again share your thoughts #GU tweeples and will see the votes.
This week’s 2nd posting of #GUPath #GradingChallenge cases (2 of 5)👇
Papillary #urothelial carcinoma, non-invasive. How will you report the grade? (2016 WHO)
Please take the poll in comment.
Again share your thoughts #GU tweeples and will see the votes.
Final poll: GP5 by 57% of 224 votes
As already commented, solid with rosette-like spaces was added to GP5 by 2014 ISUP.
I guess lack of clear spaces distinguishes this from GP4.
Thanks #GUPath tweeples for voting & informative comments! More #GradingChallenge cases to follow.
This week I’ll be posting #GUPath #GradingChallenge cases (1 of 5)👇
#Prostate carcinoma. Is this Gleason pattern 4 or 5? Or if you think it’s mixed, what’s the predominant pattern?
Please take the poll in comment.
Share your thoughts #GU tweeples and will see the consensus.
Final poll: GP5 by 57% of 224 votes
As already commented, solid with rosette-like spaces was added to GP5 by 2014 ISUP.
I guess lack of clear spaces distinguishes this from GP4.
Thanks #GUPath tweeples for voting & informative comments! More #GradingChallenge cases to follow.
This week I’ll be posting #GUPath #GradingChallenge cases (1 of 5)👇
#Prostate carcinoma. Is this Gleason pattern 4 or 5? Or if you think it’s mixed, what’s the predominant pattern?
Please take the poll in comment.
Share your thoughts #GU tweeples and will see the consensus.
Anyone seen a centered Dansby dual Heritage RC that's centered? All three of mine are OC and most of these are, too. #gradingchallenge
Handwritingchallengeหรอ ธรรมดาอะ เจอ #gradingchallenge อาจารย์กูก่อน555555555555 เห็นหล่อๆแบบนี้แต่���กรด....🌚 #ตีแผ่ชีวิตมหาลัย #finalcrisis
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