Top Tweets for #patchseq
I can only stress how much fun this fruitful collaboration was and still is. Thank you @neuronJoy and @internautderek! Looking forward to hearing your comments #paincommunity #patchseq #ionchannel #pain #itch #microneurography #transcriptomics
Happy Holidays! I’m really excited to share this preprint on using Patch-seq and other multi-modal methods to identify the molecular identity of silent nociceptors in the dorsal root gangion in pigs and humans! https://t.co/wMtn6umhIm 1/
Meet cell 485105.03.02.01... and follow its epic journey to become data through our large-scale, multi-team #Patchseq pipeline.
https://t.co/fWb5hffLrt
Thanks Jim! Below I've linked to a thread from earlier in the year. Look for more #patchseq work from us in the future including integrating with other datasets, and more novel data from islets of donors with T1D.
Congrats @bcellorg on another islet cell patch seq masterpiece. “Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state” https://t.co/paXI8jYIrX
Our new paper in @Nature_NPJ highlights transcriptomics of #Parkinson’s neurons in a dish (42 donours). Diff expression always shows something... but if it overlaps between methods (#iPSC, #iN, #PatchSeq, #10X, #bulk), gotta be real, right? 1/9 https://t.co/FmsIpyBO9U
@neuronJoy @LipovsekLab @crcadwell @hippopedoid @AllenInstitute Thanks heaps for organising. You guys made this super easy. I had lots of fun chatting with you guys about #PatchSeq both at this @SfN_Events Minisymposium and offline too!
Postdoctoral Fellow(s) in Single-cell Physiology and Phenotyping with @bcellorg
University of Alberta, Edmonton, Canada
https://t.co/QPVX6V8AD7
#ScienceJobs #scRNAseq #electrophysiology #exocytosis #metabolism #diabetes #biobanking #phenotyping #patchseq
Happy to share our latest paper, in which we used Patch-seq to connect transcriptional changes to functional changes in single striatal neurons in HD 🎉🎊 Special thanks to all our co-authors #HuntingtonsDisease
#singlecellrnaseq #patchseq @PNASNews
https://t.co/ZfRV64R8CB
Correlated scRNAseq (#patchseq) links the glucose-regulated exocytosis to mitochondrial respiratory chain assembly, and other pathways. In T2D we link impaired glucose-regulation of alpha-cell exocytosis to endocrine development signals.
We are delighted to publish this #Neuroscience #Protocol for #PatchSeq of Small #Interneurons , by Dr. Matthew S. Grubb and colleagues @GrubbLab @dev_neuro
https://t.co/2sCpy1o1ZP
New #postdoc position opening: Postdoc in #molecular profiling of the #entorhinal #cortex using #Patchseq at Department of Veterinary and Animal Sciences @UCPH_health @uni_copenhagen @CallKirstine https://t.co/uF34Xo6ftG
Hey, do you want to get electrophysiological recordings and transcriptomic data from the same small cells? Tips and tricks and (really) ALL the details in our newly published #Patchseq protocol! @LorcanBrowne @dev_neuro @KingsIoPPN
⬇️⬇️⬇️
https://t.co/dUodwi0ZVU
Our research on #Somatostatin -expressing neuron population in mouse Ventral Tegmental area (#VTA) has been just published in #eLife journal. With help of #electrophysiology, #PatchSeq, #RNAscope and #optogenetics we have described this population as fully as we could.
9/12 Two more things: Lots of data on other cell types. One challenge for electrophysiologists is challenge is the identification of non-beta-cel types. We show #patchseq can help refine models to better identify glucagon-secreting alpha-cells based on their e-phys.
7/12 In type 2 diabetes (T2D), beta-cells are impaired. Studies have reported altered single-cell gene expression, but it’s hard to know which are important. #patchseq can help with this by simultaneously studying changes in expression and function…
1/12 Here’s our paper on the dual e-phys/scRNAseq of >1300 human islet cells. I can’t emphasize enough the massive effort by @XiaoqingDai who patch-clamped ALL the cells and @JoanCamunas who did ALL the sequencing/bioinformatics. #patchseq
https://t.co/tahMp0epWc
We are soon advertising a position (#postdoc/staff #scientist) in #Data Management, #Computational analysis and/or #Bioinformatics. Help us build a program that combines datasets from cell->tissue->patient!
https://t.co/hLaYCZF0MB
#biobanking #genomics #physiology #patchseq
I’m seeking a research assistant to work on an @mssocietyuk funded project at the @UofGlasgow @iiiglasgow along with @BiottofnI and others. Experience in #electrophysiology and/or primary #cellculture essential. #liveimaging #bioinformatics #Patchseq.
https://t.co/7KErku5mN9
Many great reasons to come along to this day, including @rach_e_moore from @dev_neuro on neuronal polarity, and our very own Marcela Lipovsek talking about #patchseq in olfactory bulb dopaminergic neurons!
Book your place at the 32nd Head Group Meeting: Craniofacial & Neural Development taking place @UCLchildhealth Mon 20 Jan 2020. Fantastic speakers confirmed from @GrubbLab @kingsmedicine @LiveseyLab @Delogu_KCL @KCLstemcells @TheCrick More info & to book: https://t.co/NL6mF95TxN
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