Top Tweets for #splicemodulation
A targeted #antisense therapeutic approach for #Hutchinson-Gilford #progeria syndrome
$SRPT $IONS $WVE $STOK $PRQR
#splicemodulation @isa_aznarez @oligogirl @lab_zhou @ToshifumiYokota @timyu @Jandritu @PopplewellGroup
@HastingsLab @MayThandarAung7
https://t.co/bXiR101HyE
The administration of #antisense #oligonucleotide golodirsen reduces pathological regeneration in patients with #Duchenne muscular dystrophy
$SRPT @PopplewellGroup #splicemodulation @oligogirl @lab_zhou @ToshifumiYokota @suzanmhammond @HastingsLab
https://t.co/fqHN0zyY0k
Splicing-associated chromatin signature: a combinatorial and position-dependent role for histone marks in splicing definition
$SRPT $IONS $WVE $STOK $PRQR #NSPharma
#splicemodulation @oligogirl @lab_zhou @ToshifumiYokota @timyu @Jandritu @MayThandarAung7
https://t.co/iUzbclx2yd
Clinical Pharmacology Studies Supporting #Oligonucleotide Therapy Development: An Assessment of Therapies Approved and in Development Between 2012-2018
#antisense #gapmer #splicemodulation #siRNA #RNAi @KhvorovaL @VasantRJadhav @oligogirl @ArtKrieg
https://t.co/hnlf7ocZEl
Determination of isoform-specific RNA structure with nanopore long reads
#antisense #gapmer #oligonucleotides #ASO #splicemodulation #microRNA #longnoncodingRNA @RonBreaker @suess_lab #FamulokLab @oligogirl @lab_zhou @ToshifumiYokota @timyu @Jandritu
https://t.co/fzkvNUG0f4
Splice-Switching #Antisense #Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic 🐀
$SRPT $IONS $STOK $PRQR #NSPharma
#splicemodulation @oligogirl @lab_zhou @ToshifumiYokota @timyu @Jandritu @OlgaAnczukow @HastingsLab @MayThandarAung7
https://t.co/IISsYk2H2b
QR-313, an #antisense #oligonucleotide, shows therapeutic efficacy for treatment of dominant and recessive dystrophic epidermolysis bullosa: a preclinical study
$PRQR
$SRPT $IONS $WVE #NSPharma
#splicemodulation @oligogirl @lab_zhou @ToshifumiYokota
https://t.co/uiVmWEVsw2
#Antisense #oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a 🐀 model of Dravet syndrome
$STOK @isa_aznarez
$SRPT $IONS $WVE $PRQR #NSPharma
#splicemodulation @oligogirl @lab_zhou @PopplewellGroup
@MayThandarAung7
https://t.co/uxtOXYXMe8
#Antisense #oligonucleotide modulation of non-productive alternative splicing upregulates gene expression
$STOK @isa_aznarez
$SRPT $IONS $WVE $PRQR #NSPharma
#splicemodulation @oligogirl @lab_zhou @ToshifumiYokota @Jandritu @PopplewellGroup @HastingsLab
https://t.co/1I6NMEZih1
🐀Therapeutic efficacy of #antisense #oligonucleotides in mouse models of CLN3 Batten disease🐀
@RigoRnaIt @HastingsLab
$IONS $WVE $STOK $PRQR #NSPharma
#splicemodulation @isa_aznarez @oligogirl @lab_zhou @ToshifumiYokota @timyu @PopplewellGroup
https://t.co/6atLTo2IFF
Determination of RNA Structural Diversity and Its Role in HIV-1 RNA Splicing
$SRPT $IONS $WVE $STOK $PRQR #NSPharma
#splicemodulation #oligonucleotides #antisense
@isa_aznarez @oligogirl @lab_zhou @ToshifumiYokota @timyu @Jandritu @OlgaAnczukow
https://t.co/7QRf3Eabzi
Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and #Oligonucleotide Efficacy in Dystrophic Muscle
$SRPT $IONS $WVE $STOK $PRQR #NSPharma #splicemodulation #antisense #DMD @oligogirl @lab_zhou @ToshifumiYokota @Jandritu @OlgaAnczukow
https://t.co/CixeC5lkZB
Structural Disruption of Exonic Stem-Loops Immediately Upstream of the Intron Regulates Mammalian Splicing
#splicemodulation #oligonucleotides #antisense
@isa_aznarez @oligogirl @lab_zhou @ToshifumiYokota @timyu @Jandritu @suzanmhammond @OlgaAnczukow
https://t.co/WoSq1c0kTi
Fetal #antisense #oligonucleotide therapy for congenital deafness and vestibular dysfunction
@HastingsLab
$SRPT $IONS $WVE $STOK $PRQR #NSPharma
#splicemodulation
@isa_aznarez @oligogirl @lab_zhou @ToshifumiYokota @Jandritu @suzanmhammond @OlgaAnczukow
https://t.co/bPk4lMrtzz
Delivery of #oligonucleotides to bone marrow to modulate ferrochelatase splicing in a 🐀 model of erythropoietic protoporphyria
$SRPT $IONS $STOK $PRQR #NSPharma
#splicemodulation @isa_aznarez @oligogirl @lab_zhou @ToshifumiYokota @Jandritu @OlgaAnczukow
https://t.co/5yeU9SqyHk
Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy
$SRPT
$IONS $WVE $STOK $PRQR #NSPharma
#splicemodulation #oligonucleotides @oligogirl @lab_zhou @ToshifumiYokota @timyu @Jandritu @suzanmhammond @OlgaAnczukow
https://t.co/1ggNDxVvJy
Extracellular nanovesicles for packaging of CRISPR-Cas9 protein and sgRNA to induce therapeutic exon skipping
$SRPT $STOK $PRQR #NSPharma
#splicemodulation @isa_aznarez @oligogirl @lab_zhou @ToshifumiYokota @timyu @Jandritu @suzanmhammond @OlgaAnczukow
https://t.co/U7ZQBHtaJ6
Myostatin inhibition in combination with #antisense #oligonucleotide therapy improves outcomes in SMA
@lab_zhou
$SRPT $IONS $BIIB #splicemodulation @oligogirl @ToshifumiYokota @Jandritu @suzanmhammond #SMA #CureSMA @SMAresearch @smatrust
https://t.co/1JntkP1gG6
Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy
$IONS
$SRPT $WVE $STOK $PRQR #NSPharma
#splicemodulation #oligonucleotides #antisense
@isa_aznarez @oligogirl @lab_zhou @ToshifumiYokota @Jandritu @suzanmhammond
https://t.co/UlbgiVlhGE
Identifying and Avoiding tcDNA-ASO Sequence-Specific Toxicity for the Development of DMD Exon 51 Skipping Therapy
$SRPT $IONS $WVE $PRQR #NSPharma
#splicemodulation @oligogirl @lab_zhou @ToshifumiYokota @DuchenneNow @DuchenneRF #duchenne @CureDuchenne
https://t.co/RdapB3XVeR
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