Top Tweets for #teaes
@SagarLonialMD @US_FDA 38) Safety: the profile was generally predictable & manageable, consistent with the known effects of #CELMoDs & Dd. Any-grade #TEAEs occurred in essentially all pts in both arms; grade 3/4 in 91.7% (#IberDd) vs 70.1% (#DVd). #EXCALIBER_RRMM

Across #3studies, #ultralowdose #estradiol plus
#dydrogesterone was well tolerated among #postmenopausal #Women , with no increase in #TEAEs or TESAEs compared with #placebo.
#treatment-emergent #adverseevents
https://t.co/xt0Zldi96d

11a) 1st & foremost, this was a safety study: no test dose, all doses self-admin outside a healthcare setting. So, WAS #etripamil safe?
๐ 997 #TEAEs in the safety pop
๐ 59.8% of pts had โฅ1 TEAE
๐ 43 events in 31 pts judged as severe, occurring in 31/503 patients (6.2%).

18c) Most common #TEAEs of any grade were #nausea #vomiting #diarrhea, & most common Grade 3+ were #neutropenia #nausea & #thrombocytopenia.
๐ญThis work has now advanced to globally enrolling Ph3 ENGOT-EN20, enrolling only pts with #TP53wt #EC after response to initial chemo

31) Treatment-emergent adverse events #TEAEs were generally mild.
๐ซ 11 serious adverse events were reported by ten (8%) patients on Mava versus 20 events reported by 11 (9%) on Pbo

12c) Treatment-emergent adverse events (#TEAEs) were higher with T-DXd 6.4 mg/kg vs 5.4 mg/kg in the prespecified early cohort (PEC) and safety analysis set (SAS) (median treatment duration: 4.7/5.5 mo and 3.3/3.7 mo).

The 2nd one on #efficacy and #safety of #bempedoicacid by #sex. Significant #LDLC lowering with BA vs placebo was showed in both sexes with greater lowering in women in the #ASCVD/#HeFH. Rates of #TEAEs were similar across groups. @AHAMeetings 2020
https://t.co/xWUJXHiL7M #AHA20
๐ฑ๐ฐ #SriLanka #Ceylon #LKA #VisitSriLanka #Travel #Tourism #TTOT #BestofLankaTravels #OurWorld #ThilanW #WanderlustXL
RT|BestofLanka1: RT TravelFlute: RT pandaOfWakanda: Beautiful tea gardens of #srilanka #srilankadaily #visitsrilanka #nuwuraeliya #teaesโฆ https://t.co/W9oyrwtt2Y
#worldsymposia #friedman described study related #TEAEs #Alexion 2 patients had infusion reactions but resolved on #desensitization protocol
Beauty of #SriLanka tea estate's are unbelievable green #Nuwaraeliya
Photo vikussja_stepanova
#TeaPlantion #teaesโฆ

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