#triscend2 - Twitter Hashtag

6 months ago

Thank you @TCTMD and @TCTMD_Yael for interviewing me on the #ACC26 #TRISCEND2 #Evoque #TTVR data and how to put it into context of T-TEER vs TTVR in transcatheter tricuspid valve therapy for symptomatic severe TR @MountSinaiHeart @MountSinaiNYC @IcahnMountSinai @Dr_BrendanCarr @DrDavidReich https://t.co/O340V8Uh1J

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Dr. Gilbert Tang

@GilbertTangMD

6 months ago

Fascinating #TRISCEND2 #Evoque #TTVR data JUST OUT #ACC26 as a late breaker presented by @VinodThourani et al: - Initial baseline TR severity (62% massive/torrential) were less than TRILUMINATE RCT (71% massive/torrential) - 44.9% of pure control died @ 2 years vs 19.1% in TTVR group (p<0.001)! - No statistical (but numerical) difference in HFH @ 2 years between TTVR (26.8%) and pure controls (37.1%, p=0.171) - Non-crossovers due to unsuitable anatomy? Does this mean their TR worsens with time? - 30.2% pacemaker rate in native pts in TTVR group; ? % in crossover group? - Sustained near TR elimination @ 2 years in TTVR group and crossover group @ 1 year - Low 2 year reintervention rate Thoughts?

GilbertTangMD's tweet photo. Fascinating #TRISCEND2 #Evoque #TTVR data JUST OUT #ACC26 as a late breaker presented by @VinodThourani et al:
- Initial baseline TR severity (62% massive/torrential) were less than TRILUMINATE RCT (71% massive/torrential)
- 44.9% of pure control died @ 2 years vs 19.1% in TTVR group (p<0.001)!
- No statistical (but numerical) difference in HFH @ 2 years between TTVR (26.8%) and pure controls (37.1%, p=0.171)
- Non-crossovers due to unsuitable anatomy? Does this mean their TR worsens with time?
- 30.2% pacemaker rate in native pts in TTVR group; ? % in crossover group?
- Sustained near TR elimination @ 2 years in TTVR group and crossover group @ 1 year
- Low 2 year reintervention rate

Thoughts?

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Dr. Gilbert Tang

@GilbertTangMD

almost 2 years ago

#Evoque #TTVR #TRISCEND2 RCT showed no diff in ☠️HFH but ⬆️KCCQ 6MWD. Landmark analysis showed trend in ⬇️☠️in TTVR but not powered. Papers now in @NEJM @JACCJournals #TCT2024 @crfheart @hahn_rt @SusheelKodaliMD