HDYONZ

Huntington's Disease Youth Organisation of New Zealand || Support, Educate, and Advocate for young people impacted by Huntington's Disease in New Zealand

[HDYONZ @hdyonz]

MAY = HD Awareness Month.
This month we’ll be bringing you the People of HD in New Zealand. Please share your own stories with us 🔵🔷 #huntingtonsdisease #peopleofHD #HDawareness #HDYOnz

[HDYONZ @hdyonz]

Last Saturday, HDYO NZ representative, Micah Daniel Austria, went to Totara Springs for an awesome HD Family Day Out. Organised by MS Waikato and generously sponsored by the Lions Club of Cambridge, HD patients and their... https://t.co/f1Cl49h9oT

[HDYONZ @hdyonz]

Greetings Whanau!

In light of the recent tragedy of March 15th, 2019, it is more important than ever to encourage togetherness! Check out the upcoming event in the Waikato region where you can connect in a safe... https://t.co/xseeolQTlU

[HDYONZ @hdyonz]

Super excited about this! And super excited to have as many young Kiwi's attend as possible! https://t.co/2CqfhKtIiX

[HDYONZ @hdyonz]

Please know you’re not alone ♥️ Thanks to the brave people that shared. https://t.co/iLJndTrryx

[HDYONZ @hdyonz]

More excitement on the horizon as another therapy makes it's way past FDA approval! https://t.co/Uud0cmy2vP

[HDYONZ @hdyonz]

To start off the New Year, some... https://t.co/PDjMdyrXk4

[HDYONZ @hdyonz]

A few words from our co-chair Dr Malvindar Singh-Bains in her recent interview with 95bFM https://t.co/ilwPapYtB8

[HDYONZ @hdyonz]

Merry Christmas and Happy New Year from HDYO-NZ! In 2019 we hope to run more public awareness seminars like these! We will also be hosting more meet ups! Let us know where we should be hosting them! Feel free... https://t.co/3YMhIDRV5p

[HDYONZ @hdyonz]

Attention friends! Many of you would have heard about the drug that made international headlines which is currently being tested as an therapy for HD. For those who have questions about it, here is a FAQ sheet provided by HDBuzz clarifying the... https://t.co/4aqAIu99Fb

[HDYONZ @hdyonz]

Register for informative webinar below! https://t.co/J2Zn0VI342

[HDYONZ @hdyonz]

Hey team! We interrupt your day to share some exciting news! The "Huntington-lowering" drug which broke headlines last year, RG6042 (Roche Pharmaceuticals) is now rolling into a very large phase 3 clinical trial!

What does that mean? A big global... https://t.co/wDmqJlRFPn

[Christine Arasaratnam @Christine_Aras]

Dr. Michelle Gray spoke about the involvement of astrocytes in Huntington's disease, investigating these in BACHD mice. There is evidence of abnormal astrocytes in HD @hdyonz #huntingtonsdisease

[Christine Arasaratnam @Christine_Aras]

Juan Botas delved into compensatory versus pathogenic changes in DNA. It was also said that in drosophila motor impairments are caused by mHtt-induced neuronal dysfunction @hdyonz #huntingtonsdisease

[Christine Arasaratnam @Christine_Aras]

And now for today (saturday) we learnt from Myriam Heiman that Nme1 is protective against mHtt toxicity @hdyonz #huntingtonsdisease

[Christine Arasaratnam @Christine_Aras]

The predisposition of HD patients to heart disease was also discussed. @hdyonz #huntingtonsdisease

[Christine Arasaratnam @Christine_Aras]

We then moved onto looking at how incomplete splicing of DNA increases with CAG repeat length @hdyonz #huntingtonsdisease

[Christine Arasaratnam @Christine_Aras]

Particularly heartening is the approved use of Spiranza (ASO drug) for Spinal Muscular Atrophy in the United States @hdyonz #huntingtonsdisease

[Christine Arasaratnam @Christine_Aras]

We also looked to other neuodegenerative diseases such as SCA, XDP, and Spinal Muscular Atrophy @hdyonz #huntingtonsdisease

[Christine Arasaratnam @Christine_Aras]

Interesting fact: if you lower the CAG extension by 1 repeat, you extend the onset of the disease by around 2 years @hdyonz #huntingtonsdisease