Hector

[Developers @XDevelopers]

Announcing the hosted X MCP.

Agents now have access to the best real-time information source in the world.

Connect Grok, Cursor, or any MCP-compatible AI tool to the X API without any setup!

Check it out here: https://t.co/5MzPYwGFzD

[Marc van der Chijs @marcvanderchijs]

https://t.co/qJGPmSAe6C

[Sahil Bloom @SahilBloom]

Everyone needs to hear this…

The Empty Boat Mindset

(a visual thread)

[Prof. Feynman @ProfFeynman]

Life is too short to worry about little things. Have fun. Fall in love. Regret nothing, and don't let people bring you down. Study, think, create, and grow. Teach yourself and teach others.

[Peter H. Diamandis, MD @PeterDiamandis]

We're so close to longevity escape velocity (LEV by 2033) that your sole responsibility right now is to avoid dying from something stupid. The next 5 years will deliver more medical breakthroughs than the previous 50.

[Sahil Bloom @SahilBloom]

If you want to stand out, just do the old fashioned things well:

- Be on time
- Be well read
- Practice good posture
- Look people in the eye
- Do what you say you'll do
- Have a confident handshake

Few live up to this standard. It will never go out of style.

[Andreas Kinneging @AndreasKinnegi1]

Goed 2e gesprek met Holland Gold

[Marc van der Chijs @marcvanderchijs]

I closely work together with Claude for many hours per day, every day. We mostly use it to predict neoantigens and design mRNA molecules, a field I was completely unfamiliar with until fairly recently. And every single day there is at least one time when I exclaim 'Wow, this is truly amazing!'.

Claude is a genius, it comes up with solutions for problems that I would have never thought of. Maybe because I don't have the right scientific background, but I don't think it's just that. It thinks out of the box, and it sees connections humans don't see. You just need to learn to prompt it right and keep on asking follow-up questions.

I believe there is a short period of time to profit from this before the rest of the world will find out. That period is now. I can't explain the magic that I experience every day to people, I guess you have to use it to understand it. If you don't use Claude (or another top AI model) regularly for more than simple Google searches, you are getting left behind. Don't put your head in the sand, you will regret it in a few years.

[OpenAI @OpenAI]

Introducing GPT-Rosalind, our frontier reasoning model built to support research across biology, drug discovery, and translational medicine.

[Ole Lehmann @itsolelehmann]

Claude Mythos is like Hiroshima for software.

everything you own online, your bank, your email, your photos, your identity, is now dangerously exposed in ways that didn't exist 48 hours ago

that's why Karpathy's digital hygiene guide is probably the most important thing you can read this week

here's every step to protect yourself in these uncharted times:

> use a password manager for every account
> set up physical security keys so attackers can't log in
> enable face id and fingerprint everywhere
> randomize your security question answers
> encrypt your hard drive
> get rid of unnecessary smart home devices
> switch to signal for private messaging
> use brave instead of chrome
> switch to brave search instead of google
> mint virtual credit cards for every purchase
> get a virtual mailing address
> never click links inside emails
> use a vpn on public wifi
> block ads and trackers at the dns level
> install a network monitor to see which apps are spying on you

full breakdown of each step below:

[Claude @claudeai]

Introducing Claude Managed Agents: everything you need to build and deploy agents at scale.

It pairs an agent harness tuned for performance with production infrastructure, so you can go from prototype to launch in days.

Now in public beta on the Claude Platform.

[Marc van der Chijs @marcvanderchijs]

A physician built a 4 year medical school education with AI (sub-)agents using Claude, in just a few weeks, using 1 billion tokens. This is so cool, if I wouldn’t work 16 hours a day on my new start-up I would try the same for an economics university education and open source it.

[Sahil Bloom @SahilBloom]

Working out is the ultimate gateway drug for life improvement. Because it completely rewires your brain to view challenges differently. You start realizing that you’re in control. Capable of taking action to create outcomes. That shift has ripple effects into every area of life.

[Marc van der Chijs @marcvanderchijs]

Wow. The world has no idea what will hit us this or next year. I have said here before that I’m scared, that’s only gotten worse. Sam Altman makes some very good points though. Because the article is behind a paywall, this is a Grok summary of his blueprint. Hopefully politicians will finally wake up:

Sam Altman's "New Deal for superintelligence" blueprint outlines 6 ideas to address AI's disruptive scale, like a modern Progressive Era:

1. Public wealth fund: Seed a national fund with AI company contributions for every American to share in AI-driven growth.

2. Robot taxes: Shift from payroll taxes to capital gains/corporate income to sustain social programs as AI automates jobs.

3. Four-day workweek: Pilot 32-hour weeks at full pay, turning AI efficiency into more free time for workers.

4. "Right to AI": Treat AI access like electricity or internet—affordable for schools, libraries, small biz, and underserved areas.

5. Rogue AI containment: Gov't-industry playbooks for autonomous AI that can't be easily shut down.

6. Auto safety net: Trigger higher unemployment benefits/cash aid when AI displacement hits economic thresholds.

Altman sees urgent threats like cyberattacks and bio risks; this is OpenAI's starting point for DC debate.

[✮ Hood Satoshi @hoodtoshi]

Meta just dropped a model that predicts how your BRAIN reacts to video content.

So I built an app with it.

Paste any YouTube, TikTok, or IG link and get:
→ Predicted attention curves over your entire video
→ Emotional intensity mapping
→ Cognitive load analysis
→ A live brain visualization that lights up as your video plays
→ Exact timestamps where viewers lose focus
It's basically VidIQ on steroids — except instead of optimizing for the algorithm, you're optimizing for the human brain.
Built in a few hours using TRIBE v2. This tech is insane.

[Tuki @TukiFromKL]

🚨 do you understand what Karpathy just said..

the guy who co-founded OpenAI.. led AI at Tesla.. one of the best engineers alive..

built an app with AI.. and said the code was the easy part..

the hard part was Stripe.. auth.. DNS.. databases.. deploying it.. connecting 15 different services that all have different dashboards and different docs and different billing pages..

AI can write your entire app in 20 minutes.. but it still can't click "confirm email" on Vercel..

so the thing that's "replacing developers" can't do the thing developers actually spend 80% of their time doing..

vibe coding didn't kill software engineering.. it just proved that coding was never the job.. the job was dealing with the mess around the code.. and that mess is still 100% human.

[Andrej Karpathy @karpathy]

Software horror: litellm PyPI supply chain attack.

Simple `pip install litellm` was enough to exfiltrate SSH keys, AWS/GCP/Azure creds, Kubernetes configs, git credentials, env vars (all your API keys), shell history, crypto wallets, SSL private keys, CI/CD secrets, database passwords.

LiteLLM itself has 97 million downloads per month which is already terrible, but much worse, the contagion spreads to any project that depends on litellm. For example, if you did `pip install dspy` (which depended on litellm>=1.64.0), you'd also be pwnd. Same for any other large project that depended on litellm.

Afaict the poisoned version was up for only less than ~1 hour. The attack had a bug which led to its discovery - Callum McMahon was using an MCP plugin inside Cursor that pulled in litellm as a transitive dependency. When litellm 1.82.8 installed, their machine ran out of RAM and crashed. So if the attacker didn't vibe code this attack it could have been undetected for many days or weeks.

Supply chain attacks like this are basically the scariest thing imaginable in modern software. Every time you install any depedency you could be pulling in a poisoned package anywhere deep inside its entire depedency tree. This is especially risky with large projects that might have lots and lots of dependencies. The credentials that do get stolen in each attack can then be used to take over more accounts and compromise more packages.

Classical software engineering would have you believe that dependencies are good (we're building pyramids from bricks), but imo this has to be re-evaluated, and it's why I've been so growingly averse to them, preferring to use LLMs to "yoink" functionality when it's simple enough and possible.

[JOSE GEFAELL @ChGefaell]

What happened in 2021?