IgA nephropathy progresses to kidney failure in up to 50% of patients within 10–20 years.
On March 29th, the NEJM published the final 24-month data from APPLAUSE-IgAN and the results change the treatment landscape.
Here’s what every nephrologist needs to know 🧵
Barratt J et al. NEJM 2026. DOI: 10.1056/NEJMoa2600743
Authors from @UABHeersink report a rare case of a recurrent cerebrospinal fluid (CSF) pseudocyst causing small bowel obstruction in an adult with a long-standing ventriculoperitoneal (VP) shunt for congenital hydrocephalus. https://t.co/HvBVkgV7Cj @AHAScience#AHAJournals
Should residents & fellows bill?
A single resident can provide >$300k/yr in uncompensated care due to outdated @CMSGov rules.
Our @NEJM paper proposes a competency-based framework to capture this revenue, improve trainee pay, and offset massive debt. #MedTwitter#MedEd#GME
We are pleased to share the publication of the KDIGO 2026 Clinical Practice Guideline for Anemia in Chronic Kidney Disease (CKD), a comprehensive update to the 2012 guideline.
Read the guideline in @Kidney_Int:
https://t.co/kTGdibb77F
Visit the KDIGO Anemia in CKD Guideline website to download the guideline, executive summary, and news release:
https://t.co/Pjn6nLArSD
Co-chaired by Dr. Jodie Babitt (US) and Dr. Marcello Tonelli (CA), the guideline provides evidence-based recommendations for diagnosing and managing anemia across the CKD continuum, including dialysis and kidney transplantation.
“This guideline represents a major step forward in how we approach anemia in CKD,” said Dr. Babitt. “It emphasizes a systematic evaluation of anemia and iron deficiency, clearer guidance on when and how to use oral and intravenous iron, and integrates new evidence on emerging therapies while reinforcing the need to avoid overtreatment and to prioritize safety and shared decision-making.”
“This guideline reflects a decade of new evidence and the increasing complexity of anemia management in people with chronic kidney disease,” said Dr. Tonelli. “We evaluated a large body of randomized trial data across iron therapies, ESAs, HIF-PHIs, and transfusion strategies, with careful attention to both benefits and harms, to support consistent, evidence-informed anemia care across diverse healthcare systems, resource settings, and patient populations worldwide.”
#anemia #CKD
🔥Proud to share our latest #PKD prognostic model from CRISP IV
In ADPKD pts with normal eGFR we can predict probability of kidney failure 15 years later with C-index >0.8
Uses only TKV + data obtained in usual clinical care
@KUJGKI@KUMedCenter@fouadchebib
🔥🔥We are thrilled to announce that we matched all six fellowship positions!👏 Congratulations to Drs. Ahmadzadeh, Chandler, Kivlin, Nallapareddy, Rathi & Sugar! 🔥🎉👏🎊‼️
There’s a lot to be thankful for this Thanksgiving, but for #IgAN patients, this may be the most meaningful. 5 years ago we had ZERO drugs approved for this disease and today, we have 5 drugs with full or accelerated FDA approval!!
Thank you to all the patients who took a chance and participated in this and other clinical trials. You are why we are here today!!
https://t.co/dlttVKkdPS
NIH funded study showing that select domains of cognition improve after kidney transplantation. Cognitive impairment in CKD is at least partially reversible! Thank you @AJKDonline.
@pruthap287 Thank you for such kind words!! Will never forget the grace, positivity, and determination you have!! Your passion for cardiology is unmatched, you are a fantastic human being and physician!! You will be an asset to cardiology fellowship ♥️♥️♥️
Humbled and overflowing with gratitude for my program leadership at @namccares for believing in me for a chief resident position. Excited to lead with kindness with all round amazing friends and co-chiefs !!
#IMProud@ACPIMPhysicians@AAIMOnline