Wu et al. used MRI to characterize human subarachnoid glymphatic compartments and obtained evidence consistent with a potential perivascular shunting pathway. https://t.co/QusvW3WIXG
The BOLD signal may not be what we thought it was.
BOLD signal changes can oppose oxygen metabolism across the human cortex
https://t.co/3lWmJIdjCU
#neuroscience
🧠📈Study finds baseline perivascular space (PVS) volume is correlated with cognitive changes in patients with recent small subcortical infarcts
🎯Early PVS-targeted interventions could help prevent post-stroke cognitive impairment
Read more below👇
https://t.co/KBzspwh3k8
Raket et al. study the time course of biomarker changes in Alzheimer's disease, from the earliest detectable changes – often appearing a decade prior to symptom onset – to end-stage dementia. https://t.co/Fp7N7bV0sN
Mastenbroek et al. present a biological framework developed to categorise individuals in a memory clinic cohort based on the presence, extent, and sequence of several common pathologies. https://t.co/nHXZBEWicH
🧵
An underrecognized finding: perivascular enhancement (PVE).
How to identify it and how to reason through its differential: hop on !!
https://t.co/0AVn1iYp4U
Dementia Risk Predicted with CSF Biomarkers
Impaired movement of cerebrospinal fluid (CSF) can predict the risk of a person developing #dementia later in life
@honghui2021@Cambridge_Uni#CSF#biomarkers#brain
https://t.co/cBnQQfpSDv
🧠📈Study finds baseline perivascular space (PVS) volume is correlated with cognitive changes in patients with recent small subcortical infarcts
🎯Early PVS-targeted interventions could help prevent post-stroke cognitive impairment
Read more below👇
https://t.co/KBzspwh3k8
Donahue et al. review the anatomy and function of the parasagittal dural space, highlighting its roles in neuroimmune surveillance and in the clearance of proteins implicated in neurodegenerative disorders. https://t.co/KCzvZEWu8x
The VasCog-2-WSO criteria provide updated international guidelines for diagnosing vascular cognitive impairment and #dementia, incorporating recent biomarker advancements. https://t.co/X0D2xZ8Zx8
Anti-Inflammatory Therapy for Cerebral Small Vessel Disease: Genetic Evidence for Potential Druggable Targets
In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Sun et al. #AHAJournals
https://t.co/snKEmgEVzT
Using tau PET and plasma p-tau217 biomarkers may refine #Alzheimer trials by tracking disease progression in real-time and anticipating cognitive changes prior to impairment.
https://t.co/GBe8rQ8zy3