Bastien Rioux

MD, MSc, FRCPC | 🇨🇦 Neurologist | Clinical research fellow @EdinUniBrainSci #neurovasc | Follow ➡ @stroke_methods

[Neurology Journal @GreenJournal]

@PargolBalali Read the related editorial by @B_Rioux and Whitelely: https://t.co/EjrCLx9Z3H

[Bastien Rioux @B_Rioux]

:-)

https://t.co/Abiuc01ty7

[Stroke AHA/ASA @StrokeAHA_ASA]

Polygenic Risk Scores to Investigate the Genetic Liability to Poststroke Epilepsy

In this #BloggingStroke post, @B_Rioux discusses #Stroke article by @SanticlocMD & @CyprienRivier et al. #AHAJournals

https://t.co/tHELRJKEqf

[Stroke AHA/ASA @StrokeAHA_ASA]

Anti-Inflammatory Therapy for Cerebral Small Vessel Disease: Genetic Evidence for Potential Druggable Targets

In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Sun et al. #AHAJournals

https://t.co/snKEmgEVzT

[Stroke AHA/ASA @StrokeAHA_ASA]

What’s in a Predictor? The Case of Brain Imaging Markers for Poststroke Cognitive Impairment

In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Hassani et al. #AHAJournals @CBushnellMD @LBGoldsteinMD

https://t.co/ov7NTfW2nq

[Bastien Rioux @B_Rioux]

In this Blogging stroke, I discuss MRI "predictors" of cognitive function after stroke and explain why they are difficult to interpret clinically.

"Risk estimations in the clinic — including intuitions or ‘gestalt’ — are inherently multivariable."

https://t.co/yeb8OBeAYh

[Stroke AHA/ASA @StrokeAHA_ASA]

Can Proteomic Profiling Help Predict Incident Ischemic Stroke in the General Population?

In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Gan et al. #AHAJournals

https://t.co/sKk2yj8YyO

[UK Dementia Research Institute @UKDRI]

Research by @HuntLabEdin & @DrMcglasson (UK DRI at Edinburgh) sheds light on the mechanisms behind RVCL-S, a rare genetic disorder that affects small blood vessels.

The study identifies an important therapeutic target👉 https://t.co/GjSimnoLrq

[Bastien Rioux @B_Rioux]

@UKDRI

[Bastien Rioux @B_Rioux]

Our work led by Sarah McGlasson and colleagues from the Hunt lab at UK DRI Edinburgh sheds light on a rare genetic disease caused by DNA damage in small blood vessels

Powerful translational approach using UK Biobank and mechanistic studies on TREX1

https://t.co/1uMAKHaJUB

[Stroke AHA/ASA @StrokeAHA_ASA]

Are Neuroinflammation and Blood-Brain Barrier Dysfunction Involved in Cerebral Microbleeds?

In this #BloggingStroke post, @B_Rioux discusses #Stroke article by @Lupei_Cai et al. @CamStroke #AHAJournals

https://t.co/fc1PV88QOk

[Stroke AHA/ASA @StrokeAHA_ASA]

Can Serum Biomarkers Help Detect Hemorrhagic Transformation After Intravenous Thrombolysis in Acute Ischemic Stroke?

In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Guo et al. @NguyenThanhMD #AHAJournals

https://t.co/eyZ7Hu7hsa

[Stroke AHA/ASA @StrokeAHA_ASA]

Can Age-Stratified Genetic Analyses Help Identify Risk Factors for Stroke in Younger Adults?

In this #BloggingStroke post, @B_Rioux discusses #Stroke article by Nguyen et al. #AHAJournals

https://t.co/5cpU99vmxG

[Bastien Rioux @B_Rioux]

Can Age-Stratified Genetic Analyses Help Identify Risk Factors for Stroke in Younger Adults?

https://t.co/5PlFxT0S3B

[Stroke AHA/ASA @StrokeAHA_ASA]

Sex-Specific Genetic Association Studies Help Uncover Stroke Mechanisms

In this #BloggingStroke post, @B_Rioux discusses #Stroke article by @JaraCarcel et al. @ArenillasJF @brainbleedmd @FabregaGallego @MarFreijo @vobach3 @israelcadenas1 #AHAJournals

https://t.co/3CIZdYBxIW

[Alexandre Poppe @PoppeAY]

Nouvelle/new publication!👇
https://t.co/1fyTnxom4D
DIDO times in Québec and clinical outcomes among EVT-treated pts.
🧠 Great work from Dr Joel Neves Briard, Aymen Sahal, colleagues from all EVT sites in QC and @INESSS_Qc
@INR_CHUM

[Stroke AHA/ASA @StrokeAHA_ASA]

Early Direct Oral Anticoagulant Initiation is Generally Safe in Ischemic Stroke Associated With Atrial Fibrillation

In this #BloggingStroke post, @B_Rioux discusses @TheLancet article by Werring et al. on the OPTIMAS trial. @BoNorrving

https://t.co/SxUtF0zjEB

[UK Dementia Research Institute @UKDRI]

Did you know 300 million people live with a rare disease worldwide?

This #RareDiseaseDay, we're spotlighting @HuntLabEdin (UK DRI at Edinburgh). The lab is researching a gene called TREX1, which when faulty, causes 2 different rare brain diseases 🧬 🧠

🎥 @DrMcglasson explains ⬇️

[Bastien Rioux @B_Rioux]

Great study on plasma p-tau217 in cognitive impairment from an international collaboration involving researchers at @mcgillu
https://t.co/hENFh9d4Z5

[Bastien Rioux @B_Rioux]

2/2 New mechanistic discoveries will be facilitated through a shift towards biologically-derived phenotypes, age-stratified analyses and inclusion of diverse ancestry populations.

[Bastien Rioux @B_Rioux]

1/2 Excellent review by John Hardy (UK DRI at UCL) on the genetic architectures of neurodegenerative diseases and how our current understand of failing damage clearance systems can inform future GWASs.

https://t.co/3kPm65KMGd