This work was a great effort by many in the lab, especially @jonathanpalozzi, Swathi Jeedigunta and Anastasia Minenkova, and we thank so many others in Toronto and elsewhere who have heard the story and provided great insight and suggestions! 9/9
We are excited to share this new story from our lab! We report discovering a crucial piece of the long-standing mystery of how mitochondrial (mt) genomic integrity is maintained across generations. Summary follows: ๐งต 1/9 https://t.co/tH0Fhi1bxS
Our work suggests the exciting idea that mtDNA selection and meiosis, which are required for maintaining mtDNA and nuclear DNA fitness respectively, are genetically and developmentally linked. 8/9
Thanks to everyone for a successful #CanFly2019, especially the organizing committee: Julie Brill, Bruce Reed, @RFG_Lab, @tjsmerritt, @kramer_lab, @KimlabFlyroom, @IanDworkin, as well as all the PIs and trainees who shared their great science this past week!
@RusanLab@siekhauslab@nyuskirball@UofT @nih_nhlbi Could not agree more. Our work builds upon seminal research by both Hong Xuโs lab and Hansong Ma and Patrick OโFarrell https://t.co/bIpVNGgYDf