Years ago, I was in Ukraine and broke.
Photographer: let me take your photos and give you some money.
Me: sure.
*proceeds to pose*
Years later.
Someone: Omg! You must be making so much money off this.
Me: yes, I just enjoy living in penury.
@EmmaOkoreMD With the current standards of ART used, every patient who is regular with their treatment is supposed to achieve an undetectable viral load.
Best we can do in a case where we suspect the patient is a risk is discussing with your hospitals legal team; if they have. Naija no get.
Reperfusion injury cannot be completely prevented, but its severity may be reduced through:
1. Controlled reperfusion – Gradual restoration of blood flow with adjustments in pressure, oxygen, calcium, and pH to limit cellular injury.
2. Ischemic preconditioning – Brief episodes of ischemia before a prolonged insult, activating endogenous protective pathways.
3. Pharmacologic therapies – Antioxidants (e.g., vitamin C, N-acetylcysteine), calcium channel blockers (e.g., verapamil), sodium–hydrogen exchange inhibitors (e.g., cariporide), and anti-inflammatory agents may reduce oxidative stress, calcium overload, and inflammation.
4. Hypothermia – Tissue cooling lowers metabolic demand and attenuates reperfusion-related damage.
5. Ischemic postconditioning – Brief interruptions of blood flow at the onset of reperfusion to reduce oxidative and inflammatory injury.
In practice, controlled reperfusion and hypothermia are the most established strategies, while many pharmacologic approaches remain investigational.