I play with GABAergic interneurons in the motor cortex to relieve STN stress. C BRAINS PhD Fellow, École Normale Supérieure Paris PSL | Glasgow Alum| Notts Alum
Has anyone struggled quantifying Sst postive cells in cortex? Whats the best approach that helped? I am trying to quantify colocalisation with chrimsonR-tdtomato in M1.
Our joint study with Takaki Komiyama @takaki_komiyama is out in @Nature !
https://t.co/bW0tvl9cao
We found cell type-specific changes in the cortical circuit of Huntington’s disease mice. Optogenetic stimulation of VIP cells rescued circuit defects and improved motor function.
#eNeuro | Assessment of Cell-Type-Specific Excitatory Synaptic Strength in the Dorsolateral Striatum of Goal-Directed and Habitual Cocaine-Seeking Behavior
https://t.co/a5XC3Kgurr
Small deletions in an X-linked RNA are associated with autism in boys and alter social behavior in male mice, without affecting learning and memory, a new study reports.
By @GiorgiaWithAnI
https://t.co/x4ux8noQpm
How do some skills become second nature? MIT researchers are uncovering how the brain turns repeated actions into automatic behavior, offering new insight into learning, habit formation, and performance. https://t.co/oyCKDXx39n
🎉 🎉 🎉 Very happy to share that the Neuropixels Opto paper, on which I am a co-first author, is finally out today! @naturemethods !!! https://t.co/tIPTm0Eqyi
How does your brain filter out noise and focus enough to learn efficiently?
Our newest preprint uses intracranial recordings + computational modeling to explore how selective attention shapes learning and state representations in the human brain 🧠
https://t.co/5UdiULuAHR
1/🧵
“To be successful as a scientist, I think you really need to be curious. You need to be inquisitive. You want to know answers to stuff that you don’t have a good sense on. You have to be stubborn because you’re going to be wrong and you’re going to not get through this. You have to have a long-term perspective. You can go months, years, sometimes making painfully little progress on something – and then something happens and it’s exciting. But if you need immediate gratification, you should not be a scientist. That’s not going to work for you, because there’s very little immediate gratification in this business. You’ve got to be stubborn and you’ve got to have a long-term perspective.”
Some career advice from 2025 medicine laureate Fred Ramsdell. He shared the prize with Mary Brunkow and Shimon Sakaguichi for their “discoveries concerning peripheral immune tolerance.”
Online now: Cell- and state-specific plasticity of striatal glutamatergic synapses is critical to the expression of levodopa-induced dyskinesia https://t.co/OBhy71X3CS
Ever notice how some moments feel heavier than they should? It may be because your brain is connecting them to older memories. New research from @deSousa_AndreF at @dgsomucla suggests fear grows when experiences get linked together over time. What we feel now is often shaped by what came before. https://t.co/59xHHyJ8AT
A miniaturized ultrasound enables targeted stimulation of subregions throughout the #brain, increasing the types of tools and opportunities for studying brain function. https://t.co/K09RVuKRRM
✨🧠Postdoc position open!🧠✨
If you’re excited about neural circuits, stress, and behavior (and want to do some really cool experiments), I’d love to hear from you.
Please share!
https://t.co/bfZv2opfHr
#JNeurosci: Galvan et al. show that most GPe neurons exhibit substantial variability in firing over minutes, calling into question whether firing patterns alone can reliably define cell types.
https://t.co/pbvyVgoDp9
🚨The Sweis Lab for Translational Neuroeconomics @IcahnMountSinai is searching for a postdoc fellow! If you or someone you know is searching for a position, please share!
📄 📌Link to job flyer here:
https://t.co/dyN43q7nGX
🧠 🐁 🔬🏙️🌆🧪🧬💊🧫💡🏥
@MountSinaiPsych@SinaiBrain
Neuropath. & molecular analyses on 47 postmortem substantia nigra samples implicate ferroptosis (& to a lesser extent necroptosis) in #Parkinsons cell death; Researchers propose a “2-hit” model: early synucleinopathy amplified later by a neuromelanin-iron
https://t.co/4QSZfquNIZ
Two neurobiologists who helped decipher how the somatosensory system detects touch and pain have won this year’s Brain Prize, the largest award in neuroscience.
By @HelenaKudiabor
https://t.co/b4RFVBubiF
Researchers identify brain neurons responsible for building endurance after exercise #inmice. https://t.co/dmWsN5lD5H
J. Nicholas Betley & colleagues
@neurocellpress
Our new work is out in Science Advances. We show that neural activity in the striatum reflects not just cortical inputs, but also often-underappreciated thalamic inputs.
https://t.co/ppLG7auidL