A med student asks: "Sir, why is Rabies almost 100% fatal once symptoms start? Why can't our immune system just fight it off like other viruses?"
This is a brilliant question. The answer lies in how this specific virus completely outsmarts our body's defense mechanisms.
STEP 1: STOP THE SEIZURE NOW
Status Epilepticus - Periphery Protocol:
Step 1: Airway + O2 + Positioning
- Lateral position. Suction ready. O2 10L
- Check sugar. 25%DW or DS IV if hypoglycemic
Step 2: Benzodiazepine - 2 chances only
- Lorazepam 4mg IV slow. If no IV: Diazepam 10mg PR/Rectal
- Can repeat once in 5 min. Max 2 doses
- Why: Every minute = more neuron death
STEP 2: LOAD THE SECOND DRUG
Step 3: Anticonvulsant Load
- Phenytoin 20mg/kg IV in NS. Max 50mg/min → Watch BP + ECG
Can’t mix with D5. Causes precipitation
-OR Phenobarbitone 20mg/kg IV if no phenytoin. Slower, more sedation
Why: BZD stops it now. This keeps it stopped.
Wanted to see $Gold take out June low first then I’d be more comfortable building longs
May have to do small soon and just have orders under it incase of some spike
See how it goes
I'm breaking down this LFTs report like a pro clinician for my juniors today. A lot of you have been asking for a practical, real world way to read these. I promise you: if you read this thread to the end, you’ll never struggle with interpreting liver function tests again.
First of all remember this advice: never read LFTs randomly. Read in groups. Three groups. 🧵
Rick Rule: Gold is stupidly underowned.
Today, almost nobody owns gold.
- Rick Rule: ~0.5% of US financial assets are in gold.
- Goldman Sachs: ~0.18%.
Goldman estimates that every additional 0.01% allocation to gold would increase its price by roughly 1.4%.
For perspective, the 40-year average allocation is roughly 4%.
Historically, gold performs best when purchasing power is being destroyed.
Meanwhile, inflationary pressures continue to build:
- US M2 money supply is growing at the fastest pace in 5 years.
- The war in Iran is escalating.
- Governments around the world run massive deficits.
- Debt across the developed world continues to grow.
Yet gold remains one of the most underowned assets in the world.
Gold isn't something you buy because you're certain a crisis will happen tomorrow.
Gold is insurance...
And you buy insurance before there's an accident.
🩸 Can you name all 13 clotting factors without looking?
Most doctors remember Hemophilia A & B.
But do you remember:
• Which factors are Vitamin K dependent?
• Which pathway Factor VII belongs to?
• Which deficiency prolongs aPTT but causes no bleeding?
Here’s a high-yield summary every medical student and resident should know.
Save it for revision. 📚
#MedTwitter #FOAMed #MedicalEducation #NEETPG #USMLE #MRCP
Here is a finding that should reshape how we think about LDL and cardiovascular risk.
The Virta Health study showed a 10% average increase in LDL on a supervised ketogenic intervention for type 2 diabetes. And a 12% reduction in calculated 10-year ASCVD risk at the same time.
Let that sink in. 🧵
If you’re a HO / MO / Resident starting Emergency duty. This Slide is GOLD for you.
In ER, we’re taught “CT is normal in early stroke”. That’s half true.
If you know these 3 signs, you can spot an acute MCA stroke in <2 minutes on NCCT.
Step 1: Is the patient symptomatic?
Look for:
• Confusion
• Seizures
• Coma
• Severe vomiting
• Signs of raised ICP
➡️ If YES → Severe symptomatic hyponatremia.
Treat with 3% hypertonic saline (100 mL IV over 10 minutes) and reassess. Repeat up to 3 times if severe neurological symptoms persist.
Step 2: If not symptomatic, assess volume status.
Hypovolemic
• Vomiting
• Diarrhea
• Thiazide diuretics
• Adrenal insufficiency
• Burns/third-space losses
➡️ Treat: 0.9% Normal Saline
Euvolemic
• SIADH
• Hypothyroidism
• Glucocorticoid deficiency
• Primary polydipsia
• Low-solute intake (beer potomania/“tea and toast”)
➡️ Treat: Fluid restriction + treat the underlying cause
Hypervolemic
• Heart failure
• Cirrhosis
• Nephrotic syndrome
• Advanced kidney failure
➡️ Treat: Fluid restriction ± loop diuretics + treat the underlying disease
Step 2: Correct sodium safely.
Avoid rapid correction.
Aim for ≤8 mmol/L in the first 24 hours in patients at high risk of osmotic demyelination, with close monitoring of serum sodium.
Remember:
✅ Symptoms decide 3% saline.
✅ Volume status decides the fluid.
✅ Correction rate protects the brain.
El cortisol alto añade 5 años a tu rostro.
Destruye la insulina, te da papada y barriga, e incluso encoge tu cerebro.
Aquí tienes los 7 mejores consejos de médicos para arreglarlo:
1. Deja de hacer ejercicio por la noche.