Today in @NEJM we show that cefazolin should be the preferred agent for MSSA bacteremia
https://t.co/BCVDzDfUqL
We also show in @TheLancet that penicillin should be preferred to anti-staphyloccal penicilins for PSSA
https://t.co/X3JSm7NxJG
@snap_trial@RIMUHC1
@ImBigPharma Thats a high level but imaging pattern and risk factors matter a lot. If you labs uses standard cutoff levels for the GLM that level above 4 is very high. I usually care when it is above 0.85. I would expect to see growth on the cultures at that level so I wouldn't jump on Tx.
@PaulSaxMD Great read Dr Sax. It reminded me a similar situation with my father. I diagnosed him with right renal carcinoma during my third year of IM while I was in the US and he was in Colombia. The complexities of being the family doctor and being in a different country are tough.
What the DOTS trial of Staph bacteremia tells us:
• Dalbavancin d1 and d8 vs daily IVs for WEEKS
• No left-sided IE/CNS/prosthetics
• Dalba not superior by DOOR endpoint, but similar clinical outcomes.
Big implications for inpt care. More in link ⬇️⬇️⬇️
⚠️TYLENOL & AUTISM—RFK Jr and Trump are wrong—the largest & best study in the world in 2.5 MILLION KIDS—found no increased autism risk with acetaminophen (aka paracetamol, Tylenol) use by the mother during pregnancy. A crude unadjusted analysis found only a preliminary 5% risk, but once you adjust for family by matching using sibling controls (who didn’t get autism), the even tiny 5% risk vaporizes to 0% 📉. (Fun fact: I used to do drug safety epidemiology and have been whistleblower against big pharma when their drugs were dangerous—so I know a few things about drug safety data). Thread 🧵.
The federal HIV guidelines are facing a shutdown.
A trusted, living resource — used by clinicians, programs, and public health agencies for decades — may disappear due to “budget decreases and revised priorities.”
Big mistake.
https://t.co/AXmpdBjXNJ
@CeraGibson Estimates suggest we've lost about half of the world's original forests over human history, and a significant chunk of that was in the last 100 years.
#IDTwitter@JHMed_ID
Happy New Year Infectious Diseases colleagues!
The @IDSAInfo worked hard to advocate for the add-on billing code G0545 that can now be used when evaluating inpatient confirmed or suspected infections!