Ilan Libedinsky

PhD candidate neuroscience at the Dutch Connectome Lab, Vrije Universiteit

[Ilan Libedinsky @ILibedinsky]

🚨 New Research Alert! 🚨

Polyconnectomic scoring of functional connectivity patterns across eight neuropsychiatric and three neurodegenerative disorders
https://t.co/qg8JpZBJo2

Can we use the entire connectome to learn more about brain disorders?

@BiologicalPsyc1

[Bernardo Maciel @bernardopmaciel]

Hello! Our new study where we investigated how genetic variants shape the functional wiring of our brains using UKB was just published.
🧵 Here are our main takeaways! (1/5) 🧵

[Nathan Bell @nathanybell]

When do machine learning models actually outperform standard polygenic scores? 🤔

In our new preprint, we benchmark how non-additive genetic effects (i.e, dominance deviations) shape polygenic prediction across simulated and UK Biobank traits.

👉 https://t.co/FMbNEkIQpw

🧵 1/6

[Emil Uffelmann @euffelmann]

🚨 The preprint for our GWAS of Alzheimer’s disease (AD) is out

Preprint: https://t.co/fbZDUj3c0F

🧵

[New Scientist @newscientist]

A timeline of genetic changes in millions of years of human evolution suggests advances in cognitive abilities may have led to our vulnerability to mental illness. https://t.co/Gsq06p4r09

[Bernardo Maciel @bernardopmaciel]

Hey!!
Rachel Brouwer, Martijn van de Heuvel and I wrote a book chapter on the genetics of neuroanatomy. We discuss twin literature on heritability of brain structural traits, followed by a discussion on GWAS findings
https://t.co/YQXZSfdOHj

[Bernardo Maciel @bernardopmaciel]

Our new preprint on "The genetic landscape of heterogeneity in human functional brain connectivity" is available on medRxiv. Check it out! @MJ_Schipper, Christiaan de Leeuw, @cato_romero, @khelwegen, @DPosthu, Jeanne Savage and Martijn van den Heuvel.

https://t.co/ZcuZNKcmpY

[Cato Romero @cato_romero]

I'm so happy to share that our paper "Immune-developmental processes contribute to schizophrenia risk: insights from a genetic overlap study with height" has been published in Biological Psychiatry 🥳 https://t.co/dqGXiCntTB

[Ilan Libedinsky @ILibedinsky]

https://t.co/njt9h3VXTD

[Ilan Libedinsky @ILibedinsky]

🚨 New Research Alert! 🚨

Polyconnectomic scoring of functional connectivity patterns across eight neuropsychiatric and three neurodegenerative disorders
https://t.co/qg8JpZBJo2

Can we use the entire connectome to learn more about brain disorders?

@BiologicalPsyc1

[Ilan Libedinsky @ILibedinsky]

6/ We’ve made available the scripts to compute PCS using MATLAB, R, and Python, along with a repository of meta-analytical CSS maps for 11 brain disorders, all mapped using 25 different cortical parcellation schemes. Now everyone can compute PCS on their own data!

[Ilan Libedinsky @ILibedinsky]

8/ Many thanks to the co-authors of the study, including @khelwegen, @Marius_Gruber, @JonathanRepple, Tilo Kircher, Udo Dannlowski, and especially @martijnheuv, as well as my great colleagues at the CTG for their help and input.

[Ilan Libedinsky @ILibedinsky]

7/ Interested in learning more about this method and how to apply it? I’ll discuss this and more in a webinar on November 7, organized by the amazing @TranslationalNI @UBC_Psychiatry @DMCBrainHealth @shalailahaas @RuiyangGe @enigmabrains. https://t.co/WWuIDlI2Pn

[Translational-Neuro @TranslationalNI]

The 7th event is scheduled for November 7th! We're excited to welcome @ILibedinsky , PhD candidate from @VUamsterdam , who will be presenting their work on quantifying brain connectivity signatures by means of polyconnectomic scoring! https://t.co/u688adBQ5k

[Ilan Libedinsky @ILibedinsky]

#OHBM2024 Are you looking for an easy-to-use, interpretable connectomic marker that quantifies the presence of disease-related signatures in the brain? Visit poster 1907 to learn how polyconnectomic scores can enhance your research!

[Cato Romero @cato_romero]

I’m very happy to share that our work on the genetic overlap between schizophrenia and height is now available on @medrxivpreprint 🎉 Link: https://t.co/jyuoxxJlYJ
quick summary below (1/9)