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Online now: Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition https://t.co/O5XPfFoJxZ
Online now: The transcription factor Eomes drives a stemness program in CD4+ T cells that promotes anti-tumor immunity in response to immunotherapy https://t.co/geONFeoVxi
Online now: Analysis of West Nile disease convalescents identifies human monoclonal antibodies protective against West Nile and related orthoflaviviruses https://t.co/JDrOCyYhB8
Commensal-derived trehalose monocorynomycolate triggers γδ T cell-driven protective ocular barrier immunity. A study by Rachel R. Caspi et al. in @ImmunityCP#ASMicrobe https://t.co/hoNyntrYwD
Commensal-myeloid crosstalk in neonatal skin regulates interleukin-1 signaling and cutaneous type 17 inflammation. Read the full article by @MAD_Postdoc & colleagues in @ImmunityCP#ASMicrobe https://t.co/L4t9A1gagv
🚨New Publications featuring #PIIO Member @NandiniAacharya. Two new @ImmunityCP papers co-authored by Dr. Nandini Acharya uncover fundamental mechanisms that shape #Th17 cell identity and function. These findings advance our understanding of how Th17 cells integrate environmental, metabolic, and intracellular cues to drive #immunity, #inflammation, & #cancer, opening new avenues for future #immunotherapies.
https://t.co/EJZxR0bNyt
https://t.co/eCubpiwY8p
IT'S TOMORROW!!!
OBS Neuroimmunology Webinar — Monthly on the 3rd Thu at 12 PM ET
Aged circulating CD8+ T cells and their secreted factors drive cognitive decline
*Speaker: @SucharovJuliana@UCSF@ImmunityCP
*Moderator: @CCJerryLinPhD @MGH_RI
*Zoom: https://t.co/HUh9eGl74q
How are longevity and immunity to severe infection connected? The answer lies in disease tolerance.
Out in @ImmunityCP, we preview an exciting breakthrough by Triana-Martinez et al. on how p16High immune cells protect the host and promote healthy aging. 🧵 (1/5)
IFN-γ produced during immunotherapy induces PD-L1 expression by neutrophils with an aged phenotype that drives therapy resistance @ImmunityCP@0310Polo@karolinskainst
https://t.co/V2l6hJrvvg
💫Back2back papers in @ImmunityCP led by #DandanYang: multi-omics studies reveal how the gluococorticoid (GC) pathway restrains Th17 cell pathogenicity.
GC steroid synthesis & sensing maintain the homeostatic state of Th17 cells. @AnaAndersonLab
1/3 🧵
https://t.co/BS2oUXNYiE
Online now: Interleukin 23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity https://t.co/jcLztxv1rZ
Online now: Analysis of monoclonal antibodies against the malaria invasion complex protein RIPR reveals the structural basis for synergistic antibody protection https://t.co/KblpA8Fm05
Join our editor Dr. Jodi Gullicksrud at @AegeanConf's 1st International Conference on T Cells in Health and Disease! June 15 is the deadline for abstracts, early registration rates, and Trainee Travel Award applications. Register today: https://t.co/YoLgpg86P5 #TCells#Immunology
Online now: Activating an interleukin 4-FLT3-STAT6 axis in multipotent progenitors restores lymphopoiesis in inflammation and aging https://t.co/VJl64GwmjB