Kuchroo Lab

Lab of Prof. Vijay Kuchroo @GeneLayInst @BrighamWomens @HarvardMed @BroadInstitute. Posts by lab members unless signed by VKK. Views are our own.

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

New publication in Immunity! Researchers from the Gene Lay Institute, led by Dr. Caroline Sokol and Dr. Xueping Zhu, identified mTORC1 as a molecular switch that helps sensory neurons “remember” allergen exposure—driving heightened itch and allergic responses upon re-exposure.

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

Honored to welcome Dr. Shimon Sakaguchi, the 2025 Nobel Laureate, for a fireside chat at the Gene Lay Institute with our trainees. His pioneering work in regulatory T cells has transformed our understanding of immune tolerance. Watch the highlight below.
#GeneLayInstitute

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

Science, collaboration, and community! Yesterday we gathered for our monthly science meeting and heard from three of our talented Gene Lay Institute Postdoctoral Fellows. We love seeing our community come together to share feedback, support new research, and catch up.

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

Celebrating 34 years of the Kuchroo Lab and honoring our Director, Vijay Kuchroo! Past and present lab members came together on Cape Cod to celebrate decades of discovery, collaboration, mentorship, and hard work.A wonderful reminder of the lasting community built over the years.

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

Join the Gene Lay Institute on October 2nd for our Tissue Inflammation Workshop! Hear from leading scientists in neuroimmunology, present your research in our trainee poster session, and connect with experts. Register today!

#GeneLayInstitute

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

https://t.co/CIhywhaFht

[Kuchroo Lab @KuchrooLab]

Congratulations Marco, and welcome to the @GeneLayInst.

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

Macrophages near brain blood vessels regulate blood flow & waste clearance to protect against Alzheimer’s. @TheColonnaLab reports cMAF enables this key signaling. Congrats to Dr. Colonna, GLI's newest core faculty member, on this research! @WashUMedicine @MGBResearchNews

[Kuchroo Lab @KuchrooLab]

Dr. Kuchroo's Legacy of Stars🌟

[Kuchroo Lab @KuchrooLab]

Cape Cod 2026
#KuchrooLabReunion

[Kuchroo Lab @KuchrooLab]

Cape Cod 2026
#KuchrooLabReunion

[Kuchroo Lab @KuchrooLab]

@AnaAndersonlab @NatureMedicine @NatureComms @NorioChihara Bring on #KuchrooLabReunion2026. Sea Crest here we come!
#KuchrooLabReunion #KuchrooLegacy
@LabPeters

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

New research from @JoonHyukLee3 & @QuintanaLabHMS shows that astrocytes level-up as non-professional antigen-presenters after interactions with T cells to boost T cell pathogenicity in 🧠CNS autoimmunity.
@MGBResearch @HarvardMedical @BroadInstitute https://t.co/xaNB0GrcR0

[Kuchroo Lab @KuchrooLab]

@AnaAndersonlab @NatureMedicine @NatureComms @NorioChihara Bring on #KuchrooLabReunion2026. Sea Crest here we come!
#KuchrooLabReunion #KuchrooLegacy
@LabPeters

[Kuchroo Lab @KuchrooLab]

🧵of #KuchrooLabReunion 🌎

First up, Manu Rangachari & Gerd zu Hörste (@mzhlab), together at #MSXchange 2024 in Montreal.

We love to see our alumni getting together

[Kuchroo Lab @KuchrooLab]

@AnaAndersonlab @NatureMedicine @NatureComms A 🌏 #KuchrooLabReunion in Kyoto with @NorioChihara, VKK, & Kimitoshi Kimura 🇯🇵

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

Excited to welcome Dr. Shimon Sakaguchi to The Gene Lay Institute today for a fireside chat on scientific career journeys and advice for young researchers!

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

Thank you Dr. Sakaguchi for inspiring our trainees today! Stay tuned for video highlights coming soon.

[IdoAmitLab @IdoAmitLab]

📢 New dates for ReThink Neuroimmunology: May 24–26, 2027, at the Weizmann Institute of Science.
Join our spectacular international speaker lineup for bold science and deep discussions.
Registration is open. Space is limited: https://t.co/g79xuibxXu
#RTN2027 #Neuroimmunology

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

🎉 Celebrating 3 Years of Impact! 🎉

On June 26, The Gene Lay Institute proudly celebrated its 3rd anniversary alongside our valued members. This milestone reflects the dedication, collaboration, and shared vision of everyone who has been part of our journey.

#GeneLayInstitute

[Gene Lay Institute of Immunology & Inflammation @GeneLayInst]

What an incredible day at the @GeneLayInst 's inaugural retreat on April 27, 2026! 🎉

Watch the retreat highlights below! 🎥⬇️

#GeneLayInstitute #Immunology #Research #LifeSciences #TeamScience #ScientificCollaboration

[Xavier Lab @TheXavierLab]

Join us and @GeneLayInst on July 31st for the Annual Symposium! This year's speakers include Marco Colonna, Shimon Sakaguchi, @stefanispranger, and @victora_lab. Register using the QR code in the flyer!

#inflammation #immunity #disease #genelayinstitute

[Immunity @ImmunityCP]

Online now: A cell-intrinsic glucocorticoid biosynthesis and sensing circuit maintains a homeostatic Th17 cell state https://t.co/GEzKtRi84a

[Immunity @ImmunityCP]

Online now: Interleukin 23 promotes a pro-inflammatory Th17 cell state by stabilizing RORγt and suppressing glucocorticoid receptor activity https://t.co/jcLztxv1rZ