India has ~1 radiologist for every 100000 people.
Read that sentence again.... :((
If we get into an accident on a rural highway at midnight / a small-town doctor suspects tb in our chest X-ray, we are waiting on a tiny, overworked pool of specialists who are running on fumes. Delayed scans mean delayed treatments.
In critical care, that delay is the difference b/w life & death.
While the world was obsessed with building AI that generates catchy text / fancy avatars, a quiet team out of SINE, IIT Bombay decided to solve a real problem.
They built Endimension.
What they are actually building...
Founded by IIT alumni & AI researchers: Bharadwaj KSS, Apparao MLV & Karthik K. Endimension built a deep-learning radiology engine that integrates directly into existing hospital workflows.
Their CDSCO-approved & CE-registered AI platform does not replace doctors, it acts as an ultra-sharp pair of 2nd eyes that never gets tired:
- Detects 80+ critical abnormalities across X-rays, CT scans & MRIs.
- Flags subtle, easy to miss lesions / brain hemorrhages within secs, triaging urgent cases to the top of a doctor's queue.
- Boosts radiologist productivity by up to 4.2x, turning hrs of waiting into mins.
Now, what does it mean for Bharat....
This is not high-tech locked inside air-conditioned metro hospitals.
Endimension’s zero-footprint, cloud-native tech works on low-bandwidth setups across Tier-2, Tier-3 & rural clinical centers.
It is actively deployed in massive public health efforts like the National TB Elimination Programme (NTEP), scanning 100s of chest X-rays daily in places where a specialist might not visit for weeks.
1000+ healthcare facilities served.
1.5M+ lives touched annually.
This is what indigenous deeptech looks like when it is built for scale, resilience & true public good.
No hype, no corporate polish, just world-class engineering coming out of Powai to save lives at the last mile.
The company is actively planning to secure Series A funding (targeting the MENA region via UAE expansion programs such as Hub71 / UAE-India CEPA Startup Series). Last confirmed equity raise was the ₹6 cr Pre-Series A in April 2024 led by Inflection Point Ventures.
Endimension is also expanding to Abu Dhabi after becoming part of Hub71's innovation ecosystem.
India is not just building the clinical backbone for its own people but for the world. Keep an eye on Endimension. 🙏🙏
For centuries, Leprosy (Hansen's Disease) was treated as an incurable curse. Even after antibiotics were introduced, treatment required yrs of heavy drug regimens & nerve damage often persisted.
In the late 1970s, an Indian biochemist developed the world's very 1st immunotherapeutic vaccine for leprosy, using a harmless, non-pathogenic soil bacterium to awaken the human immune system.
While global pharma labs focused exclusively on developing chemical antibiotics to kill Mycobacterium leprae, . Dr. Gursaran Pran (G.P.) Talwar at the National Institute of Immunology (which he founded) in New Delhi realized that the real problem was immune paralysis. In severe lepromatous leprosy, the patient's T-cells completely fail to recognize the pathogen.
Talwar screened dozens of soil mycobacteria & identified a specific, non-pathogenic strain named Mycobacterium w (Mw, now classified as Mycobacterium indicus pranii).
He discovered that when killed Mw bacteria were injected into leprosy patients alongside standard multi-drug therapy (MDT):
- It re-energized the patient's dormant cell-mediated immunity.
- It accelerated bacterial clearance from the skin & nerves by up to 50%.
- It significantly reduced the incidence of debilitating painful immune flare-ups (erythema nodosum leprosum).
The Mw vaccine became the world's 1st scientifically proven immunotherapeutic agent for leprosy, later found to also boost host immunity against drug-resistant tuberculosis & certain types of tumors.
Global health agencies spent decades searching for complex synthetic molecules, an Indian biochemist looked into the dirt under our feet and found a harmless soil microbe that taught the human immune system how to conquer 1 of the oldest afflictions in human history.
If an Indian startup/defense firm wants to build rocket engines/satellite parts/surgical implants/advanced drone components, they need sub-micron precision metal parts made from heavy-duty alloys like Titanium & Inconel.
Historically, the ultra-precise 5-axis CNC machines required to carve these complex 3D parts had to be imported from countries like Germany/Japan/Switzerland at astronomical costs. To make matters worse, foreign suppliers face tight export controls on high-precision machining tech due to its dual-use potential in defense/missiles.
India had the engineering talent to design hardware, but was held back by a reliance on imported tooling & machining infrastructure.
A not so known startup Ethereal Machines is doing genuinely game-changing work for Indian deeptech & manufacturing, operating in a sector that rarely gets flashy headline attention compared to consumer tech.
Founded by Kaushik Mudda & Navin Jain out of RVCE in BLR, they hit on a fundamental bottleneck that was quietly crippling India’s hardware, aerospace & defense ecosystem.
Instead of just buying machines, Ethereal built their own multi-axis CNC machines from the ground up in India including their proprietary hardware, mechanics & complex CNC controller software. 🙏🙏
They built flagship proprietary machines like Halo, Aura & Nimbus that deliver sub 10 micron precision allowing intricate metal geometries to be carved in a single setup w/o manually repositioning the raw block.
Their early breakthrough was combining 3D printing (adding material) & multi-axis CNC milling (carving material away) into a single machine platform.
Instead of just selling machines, they run a massive 50K+ sq ft Smart Factory in Peenya, BLR operating 24/7. Startups in spacetech, drone tech, semiconductor equipment & medical devices can upload CAD designs & get aerospace-grade precision components delivered in days instead of months, cutting customer lead times by ~40%.
They became the 1st Indian company to win a CES "Best of Innovation" Award in Las Vegas for their hybrid manufacturing tech.
By controlling both the hardware & the software behind multi-axis machining, they give India's spacetech & defense ecosystem a local manufacturing fallback that cannot be disrupted by global supply chain shocks/export bans.
Top-tier deeptech investors like Peak XV Partners, Blume Ventures & Avataar Ventures backed them with major Series A & B funding rounds to set up a massive 300K sq. ft. mega-factory outside BLR.
Most people think of "Indian tech" as SaaS apps/fintech/q-com, Ethereal Machines is doing the heavy, unglamorous lifting, building the physical machine tools required to manufacture the rockets, drones, medical implants & chips of tomorrow right inside India. 🙏🙏
I want to tell you about a two-time Nobel Prize winner who figured out why humans get heart disease and almost every other animal does not.
His name was Linus Pauling. He won the Nobel Prize in Chemistry in 1954 and the Nobel Peace Prize in 1962. He is the only person in history to win two unshared Nobel Prizes.
In 1989 he published something that should have changed cardiology forever.
He called it the Unified Theory of Human Cardiovascular Disease.
Nobody listened.
@bidesh_desh@TVMohandasPai Sir, their website has an option to book appointments. Currently they are available in over 200+ location in 30 cities in India, namely Bangalore, Hyderabad, Mumbai, Delhi, Chennai, Pune, Vadodara, Dehradun, Mysore, Bhopal, Gurgaon and more.
https://t.co/gNqC8iRfmg
Most Indian women at 28 are quietly living with 4 things they've stopped questioning. Their bloodwork explains every single one.
This could be your wife. Your girlfriend. Your sister. Your mother.
→ Periods that have gotten heavier, shorter, or weirder
→ Belly weight that stays no matter how clean she eats
→ Hair thinning at the crown, breakouts at 30 on the jawline
→ Tired and anxious in a way no amount of sleep fixes
She isn't being dramatic. She isn't lazy. She isn't "just like that."
Here's what's actually happening, and what she can do about it without spending a rupee on tests first:
SHOCKING:
In 1969, Stanford psychologist Philip Zimbardo left 2 identical cars on the street:
- one in wealthy Palo Alto,
- the other in criminal Bronx, NYC.
But, one was DESTROYED immediately.
The other untouched for days.
The reason will make you question reality:
The Palo Alto car was stripped clean within 10 minutes. License plates gone, battery ripped out, seats torn open, windows smashed. Respectable families walked by and watched it happen. Some even helped.
The Bronx car sat untouched for over a week. Kids played around it. Adults walked past without a glance. Nobody took anything.
Zimbardo had stumbled onto something that shattered every assumption about human nature, social class, and criminal behavior.
The destruction started when Zimbardo himself raised the hood and removed one piece. Within minutes, passersby began taking parts. Once the car looked slightly damaged, it became fair game for total annihilation. Families loaded station wagons with pieces. Well dressed adults yanked out the radiator while their children watched.
The Bronx car remained pristine until Zimbardo intentionally damaged it the same way.
Then it too was destroyed within hours.
What Zimbardo discovered was that vandalism has nothing to do with poverty, desperation, or criminal neighborhoods.
It has everything to do with *permission*.
The moment something appears abandoned or broken, it sends a signal that normal rules have been suspended. That signal gives everyone around it psychological permission to break rules they would never break otherwise.
This became known as Broken Windows Theory.
Small signs of disorder and neglect invite larger acts of disorder and neglect. A broken window left unrepaired becomes a message that nobody cares, nobody is watching, nobody will stop you from breaking more windows.
Cities started fixing graffiti within hours instead of leaving it for weeks. They replaced broken streetlights immediately. They swept up trash before it accumulated. Crime plummeted. New York subway crime dropped 75% just from removing graffiti and fare jumping.
But the psychological mechanism runs deeper than urban policy.
Every environment you enter is constantly communicating its rules through barely visible signals. A clean, organized space whispers that precision matters and sloppiness will be noticed. A cluttered, chaotic space shouts that anything goes and nobody will care if you add to the chaos.
Your brain reads these signals faster than your conscious mind processes them. You straighten your posture in a formal office. You speak more quietly in a library. You walk faster in a run down neighborhood. You smile more in a beautiful park.
What looks like environmental influence is actually environmental *permission*. The space tells you what behavior is acceptable, and you unconsciously calibrate yourself to match.
This explains why the same person acts completely differently in different contexts. Why honest people steal hotel towels. Why polite people become aggressive in traffic. Why disciplined people overeat at parties. The environment grants or revokes permission for behaviors that have nothing to do with who you think you are.
The most successful people understand this and design their environments to give them permission for the behaviors they want and remove permission for the behaviors they want to avoid.
A musician fills their space with instruments within arm's reach. A writer removes every distraction from their writing space. An athlete surrounds themselves with gear that makes movement inevitable. They create environmental permission structures that make good choices automatic and bad choices require effort.
The Zimbardo experiment revealed that human morality is far more contextual than anyone wanted to believe. Ethical behavior requires environmental support. Remove that support, and ordinary people become capable of extraordinary destructiveness. Add that support, and destructive people become capable of extraordinary restraint.
Your character is not as fixed as you think. Your environment is editing your personality every moment of every day.
The car experiment ended 50 years ago.
The permission structures around you are still running the experiment today.
"If you let motivation dictate your actions, inertia conspires to keep you in place.
Action creates progress. Progress creates momentum. Momentum creates motivation."
— @farnamstreet newsletter today!
https://t.co/Pgb5deHF6w
The year is 1948. India has just become free and is trying to have a tryst with destiny. And in a country with endless possibilities, you are a 27-year-old man from an affluent family.
You have also studied in prestigious institutions like Loyola College and College of Engineering Guindy and have been given a scholarship from the Govt of India to go to the USA and study Dairy engineering.
You go to the USA and realize that studying metallurgy and nuclear engineering is more useful and interesting than studying techniques of extracting milk from cows. You follow your instinct and successfully complete your course.
You are now a nuclear engineer. And in a world that has just gone nuclear, the opportunities you have are limitless. The world is at your feet.
Then the Govt of India becomes a reverse Lannister calls in its debt. They want you to work for them for a limited period as an obligation to whatever they did for you.
You have no choice but to come back.
You hope you are sent to glamourous locations like Bombay or Madras where you can spend your obligatory time in comfort and luxury. You are an America Return Nuclear engineer after all.
But the Govt of India cares as much about your designations and qualifications as a Nokia 3310 cares about a drop. So, they play a cruel joke upon you.
They send you to a small decrepit town in Gujarat which doesn't even have electricity. Your accommodation is a rundown Garage and the only sign of life around you are the mosquitos, who are trying to taste your blood.
The town is called Anand. And the only Anand you have there is its name. Else it is all despair.
You, an affluent gentleman from south India, who doesn't speak a word of Gujarati, who has never lived in a village, are now stuck in a god foresaken village in the middle of nowhere. And You want to get out of this god forsaken place on the first chance you get.
Then something happens.
You start going around the town. You start speaking to people. You understand their way of life. You understand what they want. Without you realizing you start falling in love with the place. You want to do something for them.
And then you create a revolution.
A revolution that has changed the face and fate of India.
A revolution whose gifts we are still reaping 65 years after it started.
And You are the one who started it all.
You are Dr Verghese Kurien.
Operation Flood was, is and will be one of the greatest movements India has ever had.
We went from a country that used to import milk powder from New Zealand and other countries to becoming the largest milk producing country in the world, in 30 years.
It gave livelihoods to close to more than 100 million farmers over the years and has lifted more than 50 million people out of poverty and starvation. If you count the people emancipated by Operation flood, it would be the 30th largest country in the world, ahead of Spain, South Korea and Argentina.
Today, we move the global dairy market and it is singularly because of Dr Kurien.
And he didn't stop at dairy.
He realized that India was heavily dependent on Southeast Asia for its edible oil needs. So he got all the oilseeds growers together and started Dhara, India's own edible oil brand.
He so thoroughly disrupted the edible oil industry that for a brief period of time, he significantly reduced our dependance on palm oil.
Unfortunately, our babus intervened and as they usually do, destroyed it all. But that's the story for another day.
When Karnataka's Cocoa farmers went to him to seek salvation from Cadbury's oppression, he created Amul Chocolates and created a big dent in their market share. He also ensured Cadbury treated the farmers with a lot more respect and fairness, now that the farmers had option.
When Indira Gandhi complained about farmers not getting fair price for their vegetables, he started Safal, a vegetable selling co-operative under the NDDB umbrella and made it a success.
Now most of this is known.
But what we don't know more about was Dr Kurien the innovator.
Dr Kurien and his friend JJ Dalaya were the first in the world to synthesize buffalo milk and convert it to powder. This allowed us to store and supply milk during times of deficiencies.
He was the first to create condensed milk or as you call it, Milkmaid / Mithai Mate, from buffalo milk and ended Nestle's monopoly in this segment for good.
He was also the first to pack a dense substance as oil in a Tetrapak, something that their own Swedish engineer's thought was impossible. He made it possible.
I can keep going on and on.
In today's world, words like Legend, GOAT, superstar are thrown around very very loosely.
People who hit balls with a stick, give useless expressions on a giant screen and make cringy unwatchable 30 sec videos on some apps or crack some vulgarly unfunny jokes are given these epithets today.
So, what would you call a guy who saved India from hunger and starvation? What would you call a guy who prevented India from malnutrition and stunted growth? What would you call a guy who made a basic commodity like milk, accessible to a billion people?
We don't have words for that. Maybe we need to invent some.
One more very commonly misplaced word today is disruption.
Anything and everything are disruption now. The development of an app, delivering grocery or food in 10 minutes or writing an additional line of code are all what passes off as disruption today.
That is not disruption.
Disruption is where you create something that changes the lives of people forever. Disruption happens when what you create, rewards people for Generations.
Disruption is where you help poor farmers break the vicious circle of poverty and throw them 354 steps up the economic ladder
Disruption is not how you change how people do certain things; Disruption is when you change the people themselves.
Dr Kurien was India's first and the greatest disruptor.
Dr Kurien is India's true GOAT.
So, Happy Birthday Dr Kurien. India is grateful that we had you walking on our soil. Thank you!!
P:S: The attached image is that of the recreated Garage that Dr Kurien first stayed. Garages have a unique connection to the world of tech, as a lot of tech companies started from there and are worth some bajillion dollars today.
This is a Garage that lifted 60 million Indians out of poverty.
With all due respect to HP and Google, this is the greatest Garage of them all.