Luke Pattison

Research scientist interested in inflammatory pain 🔬 👨🏼‍🔬 ✌🏼

[Luke Pattison @interlukein]

Still time to submit your latest work on #inflammatorypain to our special issue of @Cells_MDPI focussed on the Molecular Mechanisms of Inflammatory Pain.

We’re accepting manuscripts until September - if you have something suitable in the pipeline, please get in touch!

[Luke Pattison @interlukein]

Organising a special issue of @Cells_MDPI highlighting recent advances in inflammatory pain mechanisms.

If you’re looking for a home for new data, or a review on #inflammatorypain, please get in touch!

[Luke Pattison @interlukein]

Please help out if you can! 🙏

[Ewan St. John Smith @psalmotoxin]

Do YOU live with joint pain?

Do YOU experience poor pain management?

Have you got 2-minutes to tell pain researchers about it?

If yes 👉 https://t.co/PzGN5KvsdD

We hope to gain insight into lived experience for those with joint pain & involve people in our #PainResearch 😃

[Ewan St. John Smith @psalmotoxin]

At 13:00 our @UnivCamPharm lab will be live @SfNtweets!

Poster N3 sees @mayadannawi presenting on overexpression of Prdm12 in the adult sensory nervous system

Poster O6 sees @interlukein presenting on loss of Piezo2 in colonic sensory neurons with age

Please drop on by 😃

[Luke Pattison @interlukein]

Excited for @SfNtweets #SfN2025 in not-so-sunny-today San Diego! 🧠 👨‍🔬 🔬

I’ll be presenting our latest work on Piezo2 👈, colonic control 💩 and aging 👵🏻 on Wednesday, 1-5 pm at board O6 - come say hi! 🙃

[Lauren Slosky @LaurenSlosky]

Hooray!! The first major product from the lab is out today @Nature.

Small molecules that bind the GPCR-transducer interface change G protein subtype selectivity in predictable ways, enabling rational drug design.💥

Check it out! 👉https://t.co/oO21BkoxVQ

🧵👇

[Luke Pattison @interlukein]

Great summary of our latest work - a real Team Science effort! 👥 🐭

[Osteoarthritis and Cartilage Journals @OACJournal]

The sphingolipid sphingomyelin 34:1 is upregulated in the synovial fluid during OA. This study shows that SM34:1 causes inflammatory pain in mice and induces neuronal hyperexcitability. Great work: @psalmotoxin @interlukein @mayadannawi @LanhuiQiu @BeckyRickman @UnivCamPharm

[Luke Pattison @interlukein]

I am currently curating a Special Issue for @Cells_MDPI on “Molecular Mechanisms Underlying Inflammatory Pain.”

If you are working on, or planning a suitable manuscript, I would be delighted if you would consider submitting it to our issue.

https://t.co/SAKZRNuqLH

[Luke Pattison @interlukein]

Proud to watch my Pegasus Scholars students presenting on targeted cancer therapies today, after a week exploring the formation, functions, faults and fixing of proteins! 🔬

Glad to support Robinson College’s excellent widening participation initiation for another year! 👨‍🏫

[Luke Pattison @interlukein]

An inspiring week of meetings! 💡

@CamNeuro symposium and the inaugural meeting of the GPCR-UK network! Stepping into the lab with fresh enthusiasm this morning!!

[Ewan St. John Smith @psalmotoxin]

A couple of days of neuroscience excellence at the 8th @CamNeuro Symposium: Interventions & Recovery.

So many great talks, loads of representation from our lab showcasing what everyone has been up to, & insightful public panel discussion on dementia!

[Luke Pattison @interlukein]

If you have #osteoarthritis which causes you #pain, please consider answering my 2 minute survey below 👇

[Luke Pattison @interlukein]

👋I’m developing a proposal to investigate how pain changes with progression of osteoarthritis (OA). 🦴⚡️

If you have OA, I’d love to hear how your experience with pain has changed over time - please consider answering this quick 10-question survey! 🙏

https://t.co/UGzTw3krCm

[Luke Pattison @interlukein]

👋I’m developing a proposal to investigate how pain changes with progression of osteoarthritis (OA). 🦴⚡️

If you have OA, I’d love to hear how your experience with pain has changed over time - please consider answering this quick 10-question survey! 🙏

https://t.co/UGzTw3krCm

[C-COMP @MSKPainCenter]

https://t.co/yASiWdl5ET
New preprint from the lab: Targeting piezo2 to treat osteoarthritis pain

[Luke Pattison @interlukein]

Still got it! ⚡️

[Luke Pattison @interlukein]

🤩 geeking out at Geneva light festival last weekend - double helix 🧬 & neuron 🧠 #genevalux

[Luke Pattison @interlukein]

📣 Calling fellow ECRs studying the contributions of GPCRs to pain and/or analgesia!

🧠 Interested in presenting at #SfN25 in San Diego in November?

🙏 Please drop me a message - looking for last few speakers for a mini symposium proposal!

#PainResearch #Neuroscience

[Luke Pattison @interlukein]

📣 Calling fellow ECRs studying the contributions of GPCRs to pain and/or analgesia!

🧠 Interested in presenting at #SfN25 in San Diego in November?

🙏 Please drop me a message - looking for last few speakers for a mini symposium proposal!

#PainResearch #Neuroscience

[Luke Pattison @interlukein]

Exciting project, great mentor, lovely Cambridge - get applying!

[Ewan St. John Smith @psalmotoxin]

🚨 Excited to announce that we are hiring 🚨

If bowel disease, pain, & naked mole-rats are your thing then we have the perfect opportunity for you 😃

This @ChatGPTapp image shows a naked mole-rat with visceral pain, but they actually appear resistant #PainResearch

[Luke Pattison @interlukein]

Research Showcase of our latest work investigating the role of acid-sensitive receptors in inflammatory joint pain! 💊

https://t.co/quL5v73hOP

[Luke Pattison @interlukein]

@PNASNews Special thank you to @mayadannawi for supporting revision experiments! 🙌🙌🙌

[Luke Pattison @interlukein]

Very happy to share the published version of this work - out now in @PNASNews - riding the year out on a high! ✨

https://t.co/eLV2N4ztKg

More on this work below 👇

[Luke Pattison @interlukein]

Very happy to share our ✨ NEW ✨ preprint!

Activation of the proton-sensing GPCR, GPR65 on fibroblast-like synoviocytes contributes to inflammatory pain.

https://t.co/3oDoh36aVL

Keep reading for a summary of what we found… 🧵[1/10]