Irena Feng

studying neuronal vulnerability in Alzheimer's • @BU_MDPhD candidate • she/her 🏳️‍🌈 || *mostly on bsky now @ irenafeng*

[Irena Feng @irenafeng]

preprint alert! 🤭

[bioRxiv Neuroscience @biorxiv_neursci]

Cell-type specific profiling of human entorhinal cortex at the onset of Alzheimer's disease neuropathology https://t.co/5RiPa3mV2q #biorxiv_neursci

[Boston U Chobanian & Avedisian School of Medicine @BUMedicine]

Congratulations to BU’s Vickery Trinkaus-Randall, PhD, and Steven Borkan, MD, on their multi-PI T32 NIH grant to help recruit, train and inspire MD/PhD students to become clinician scientistshttps://bit.ly/44brH0e

[Irena Feng @irenafeng]

if anyone wants to chat more about my poster, feel free to reach out anytime!

[Irena Feng @irenafeng]

Wrapped up #KSNeurodegen25! It was so fun chatting with people about my poster, making new friends, and enjoying the scenery and weather 🤩 Thanks to @KeystoneSymp for hosting this conference (and for my brand-new coaster from winning musical bingo!!!)

[Chelsy Eddings, PhD @Chelsy_Eddings]

Fresh preprint of some of my PhD work released today: if you like human synapses, STED and time-resolved EM check it out!
"Ultrastructural membrane dynamics of mouse and human cortical synapses" https://t.co/hOa4gNCMIx

[Suzanne Tharin MD PhD @SpineTharin]

Just out from our lab with @MariaGalazoLab miR-193b-365 microcluster downstream of Fezf2 coordinates neuron-subtype identity and dendritic morphology in cortical projection neurons: iScience https://t.co/s39asUVRoM

[BU MSTP Program @BU_MDPhD]

Happy Thanksgiving from our MD-PhD family! Everyone showed off some major cooking chops for an impressive potluck spread 🥳🥳🥳

[Sergiu P. Pasca @Sergiu_P_Pasca]

Today we introduce human neural loop #assembloids created from 4 parts derived from stem cells to study the cortico-striato-midbrain-thalamo-cortical pathway and to model neurodevelopmental disease

Work led by the remarkable Ji-Il Kim
and Yuki Miura in the lab. Also in collaboration with the @marius10p lab at @HHMIJanelia

Video shows a four-part neural assembloid displaying emergent synchronized activity after a couple of hundred days of integration

[BU MSTP Program @BU_MDPhD]

Some highlights from another great Annual Retreat this Saturday! A huge thank you to our keynote speaker Dr. Aly Elezaby
@alyelezaby
for an inspiring and fascinating talk on his research on troponin I and his path to starting his own lab!

[Joseph Takahashi @CircadianClocks]

Circadian Rhythms Tied to Changes in Brain Morphology in a Densely Sampled Male https://t.co/W73X0ZRwUc

[Hanieh Falahati هانيه فلاحتى @HaniehFalahati]

When we think about communication between neurons, we often think about synapses. But as you can see in this week's #EM_Monday images, the cell body of neurons can come into contact with each other, and this contact area is huge compared to synapses. So do the neurons use...(1/n)

[Celeste Karch @karchlab]

Live-cell visualization of tau aggregation in human neurons 🤩 https://t.co/RZbE6yuV4b

[Boston University Diversity & Inclusion @BU_Diversity]

Join @BUAnatNeuro for an Emerging Scholars Program on Brain Diversity in Health and Disease. 🧠

Stop by this Thursday to hear talks from amazing scholars!

Join via Zoom: https://t.co/2O31t7EJu0

[Irena Feng @irenafeng]

Had a blast playing @CritCareGame tonight! Who would've thought the real killer in the ICU was pager alerts all along... 😂

[BU MSTP Program @BU_MDPhD]

We had our first social event of the year yesterday!

Welcome to the new M1s and welcome back to everyone else :)

[Boston U Chobanian & Avedisian School of Medicine @BUMedicine]

We have a very special guest walking the stage today with our new students #WhiteCoatCeremony2024

[Elise A. Mitchell @byeliseam]

Knowing there was a shortage of article reviewers during and after 2020, I decided to say yes to every article review request I felt qualified to do. I've now reviewed nearly a dozen and have some random insights to share, mostly for grad students and early career folks.

[Irena Feng @irenafeng]

New water bottle! Thanks @TwistBioscience 😊🙏

(Twist also has stickers sometimes with your order - love them for their DNA synthesis AND the free lab merch haha)

[Dan @MoakleyDan]

1/ Very happy to share that our preprint is now online! Check it out here: https://t.co/OPKWApLmVp In the study, we model RNA alternative splicing regulation in the neocortex and validate both neuron type-specific and type-orthogonal regulatory programs. Read on for a summary!

[Patrick Hsu @pdhsu]

See our previous thread on preprint here: https://t.co/z82IcKfGY7

Bridge RNA recombinases encode a mechanistically new class of guide RNAs

They are bispecific, unlike the CRISPR (2012) or RNA interference (1998) guide RNAs that specify only 1 target for a simple scissors cut