Istesso

Restoring repair for lifelong health

[Istesso @istesso]

Istesso announced the initiation of dosing in IST-03, a Phase 2 clinical trial evaluating leramistat for rheumatoid arthritis-associated sarcopenia: https://t.co/OGiUNBFMZG

[Istesso @istesso]

New data show that Istesso’s first-in-class oral regenerative medicine, leramistat, can restore and even enhance muscle quality and strength in models of aging and chronic disease. Is this the beginning of the end for age-related muscle loss? https://t.co/XXDIdIEt4n

[Lisa @DrugDiscoverer]

Lower gravity, more radiation= more cellular stress, muscle and bone loss (and bone loss doesn’t recover fully on return to earth). To populate moon cities we’ll need medicines that protect muscle and bone, and health, together. @istesso

[Lisa @DrugDiscoverer]

@vkhosla @Vero_Bioscience The logical next step if these clocks can predict organ aging is to prevent deterioration before diagnosis by adaptive repair to restore function. @istesso

[Lisa @DrugDiscoverer]

Changes map to areas of failed repair… and drive aging, but is it the epigenetic change that drives the failed repair, or failure to repair that drives the epigenetics? And what happens when we restore capacity to repair? @istesso

[Lisa @DrugDiscoverer]

Today our team @istesso publish data showing that we can elicit tissue repair in models of autoinflammation/immunity and fibrosis via a single metabolic switch.

[Istesso @istesso]

This RA Awareness Week we are supporting @NRAS_UK to shine a light on #RheumatoidArthritis and the devastating impact #RAdrain has on patients’ everyday lives. We agree everyone should be able to live the life they want to live without pain.

[Istesso @istesso]

On our way to the London Stock Exchange where our CEO Lisa Patel will be presenting Istesso as part of the ‘Future of Healthcare Investment Forum 2023’. We're honoured to be invited and look forward to bringing important conversations to the table regarding healthcare.

[Istesso @istesso]

Last week’s annual EULAR Congress offered a vital forum to discuss rheumatic diseases 🧬 Lots of important questions were asked, highlighting the need to support patients more. We’re still a way off where we need to be, but it’s great to see progress.

[Istesso @istesso]

🌍🩺 On #WorldwideAutoimmuneArthritisDay & #InternationalClinicalTrialsDay, we thank our trial participants & staff, as we raise awareness of these debilitating diseases and envision a future that transforms patients' lives. Read why we must do better: https://t.co/oujsN58bCk

[Istesso @istesso]

Last night we celebrated 20 years of @IPGroupplc's outstanding support for science and innovation @sciencemuseum. Istesso’s Executive Chair, @biotech_CEO, led a panel discussion with inspiring speakers including Dame Kate Bingham and Maggie Aderin-Pocock MBE #sciencematters

[Istesso @istesso]

It’s #InternationalWomensDay and at Istesso we’re so inspired by the women who work with us every day.

Let’s #embraceequity and get more #womeninscience #womeninbusiness #womeninstem

Who are the women that inspire you?

[Istesso @istesso]

Our CEO Lisa Patel recently spoke to Tom Froggatt for his Careers in Discovery podcast. To hear all about Lisa’s story, what motivates her and some fascinating insights into how Istesso came to be, head over to the news page on our website where you can find the link in full.

[Parkwalk @ParkwalkAdvisor]

To celebrate Intl Women’s Day 2021, we wanted to highlight 3 of our portfolio co's who are led by successful females. Read our interviews with Giorgia Longobardi, CEO, Cambridge GaN + Jane Osbourn, Chair, @Mogrify_UK + Lisa Patel, CSO @istesso

https://t.co/1iFx8OmuWu

#IWD2021

[IP Group - visionary ventures @IPGroupplc]

Congratulations to our p/f company @istesso on raising a total of £10m - https://t.co/hbul4vEsNg - to help finance their important work in the field of immunometabolism. @biotech_CEO @DrugDiscoverer #backinginnovation

[Istesso @istesso]

Very pleased to have Sir Keith Peters and Peter Allen join us as NEDs today https://t.co/CQk2imOXUq #istesso #immunometabolism

[IP Group - visionary ventures @IPGroupplc]

Prospects for our biotech co @ModernBio look "exciting, impressive" according to the live audience vote @biotech_CEO

[Istesso @istesso]

Clinical trials are the lifeblood of new medicines. Thank you to all our partners for supporting and facilitating ours. #Clinicaltrialsday

[Lisa @DrugDiscoverer]

Delighted that @ModernBio made it to the @BIA State of the Nation- the biggest UK single asset deal of 2014 https://t.co/KGAhgAu0mi #ukbsf

[Jonathan Trethowan @JBTrethowan]

Awesome achievement - congratulations to the @ModernBio team https://t.co/UuS3RULgL3