Tapasree Roy Sarkar (Sarkar Lab)

Assistant Professor, #CancerResearcher, #breastcancer, #tumormicroenvironment, @ TAMU_biology, Ph.d. @purdueABE, postdoc @MDAnderson, @NCI

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

We (Biology, Statistics and Health Science Center of Texas A&M University)are hosting a symposium on ‘Cancer: Basic Science to Bioinformatics’.
Free registration @
https:/iamcs.tamu.edu/4th-annual-bioinformatics-symposium/.
With @SenduraiMani @tarumurmur @irtisha_singh

[TAMU Biology @TAMU_Biology]

A groundbreaking study from the lab of Dr. Tapasree Roy Sarkar was recently highlighted in Forbes Magazine, for identifying the critical link between circadian rhythm disruption (CRD) and breast cancer. Read the full article from Forbes here: https://t.co/0lWV58iKSx

[Professor Erwin Loh @erwinloh]

Disrupted Circadian Rhythms Fuel Aggressive Breast Cancer

Disrupted circadian rhythms from night shifts or irregular sleep schedules can fuel breast cancer risk.

Working the night shift, frequently flying across time zones or keeping an irregular sleep schedule does more than just leave us exhausted; it can fuel the risk of aggressive breast cancer. Exactly how and why this happens has remained a mystery, until now.

A new study sheds light on this elusive link, finding that circadian disruptions change the structure of mammary glands and weaken the immune system’s defenses, all the while pointing toward a new way to counteract these effects.

To investigate these effects, the researchers used two groups of genetically engineered models that develop aggressive breast cancer. One group lived on a normal night-day schedule, while the other lived on a disrupted light cycle that threw off their internal clocks.

The findings, published in Nature group journal Oncogene, were striking.

Typical models develop cancer around the 22-week marker. The circadian-disrupted group, however, showed signs of cancer much earlier — at almost 18 weeks.

Tumors in circadian-disrupted models were also far more aggressive, and far more likely to spread to the lungs, a key indicator of poor outcomes in breast cancer patients.

Source in comments.

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

Circadian disruption alters mammary gland morphology and accelerates aggressive mammary tumorigenesis
#oncogene #nature

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@MaraShermanLab @TheMarkFdn Congratulations, Mara!!!

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

Women’s Health, Breast Cancer Awareness Month, Oct’24: Invited talk @nVent Global Women’s Network
#BreastCancerAwareness #BreastCancerAwarenessMonth #BreastCancer

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

#latepost
Had a great time visiting Vanderbilt university as a SEC scholar … Thanks @marjanrafat for being an amazing host!

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

Symposium ‘Cancer Research: Basic science to Bioinformatics’, on Oct 11th, at Texas A&M University, with @TAMU_Biology @TAMUArtSci @AlexCarlKeene @mahulchak @Irtisha_Singh @TAMUstats

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@SGoswamiMDPhD @DeblinaRC @RaiPratishtha @MDAndersonNews Congratulations!!!

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@RafatLab Thank you so much for hosting me.. I had a great time!!! Thoroughly enjoyed our brainstorming session… and our sweet treats 😄

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@RafatLab 😄😄😄

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@AKGaharwar @Irtisha_Singh @NatureComms @Kanwar_Abhay08 @tamusystem @TEESresearch @tamucommedsci @MITOCHONDRIAMED @Mito_News @MitoAging @BMESociety @bmentamu Congratulations @AKGaharwar @Irtisha_Singh and team

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@ola_jhumie Congratulations!! So proud of you 🤗🤗🤗

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

Thank you so much, Dr. Simon, for visiting us and for the wonderful seminar!!! @TAMU_Biology @PennMedicine @TAMUArtSci

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

So excited to host Dr. Celeste Simon from #upenn #upenmedicine #tamubiology on Sept 10th.

[Olajumoke Ogunlusi @ola_jhumie]

It was a wonderful experience presenting my research at the mechanisms & models of cancer meeting @CSHL. Thank you to my amazing mentor @itsTaps and @TAMU_Biology. I also met the wonderful @PamSharmaMDPhD, and enjoyed her talk on immune checkpoint therapy. #cshlcancer24 #phdlife

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@ola_jhumie @CSHL @TAMU_Biology @PamSharmaMDPhD So proud of you Ola!

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@NinaSteele17 @Momademia Congratulations!!!

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@RonDePinho So sorry to hear your loss. My condolences to you and your family!!

[TAMU Biology @TAMU_Biology]

Congratulations to Tapasree Roy Sarkar on her SEC Faculty Travel Program Grant, where she'll be visiting Vanderbilt School of Medicine to collaborate & share her work on how different environmental factors, biological cues, & therapy can alter the breast tumor microenvironment!

[Tapasree Roy Sarkar (Sarkar Lab) @itsTaps]

@NinaSteele17 @Momademia Congratulations!!best wishes