Jennifer Renaud

Cardiac Imaging Research Scientist

[Venk Murthy MD PhD @venkmurthy]

**New Paradigm in Cardiac Perfusion Evaluation**

Quantitative measures of blood flow from PET have been a huge advance and are driving PET adoption. Until recently, these were generally computed globally or across large regions (e.g. vascular territories).

Our group has now developed and validated a framework for high-resolution regional quantification of blood flow and integrating this with regional perfusion defects called iMFR.

Enables better discrimination of:

* diffusely impaired perfusion - microvascular/vasomotor dysfunction with strong prognostic implication

* focally impaired perfusion - related to epicardial stenoses

This review discusses the approach and summarizes the prognostic and diagnostic data to date.

🔗 Free @JNCjournal access link in reply 👇

🙏 contributions from @j_m_renaud (lead author) @alexispvpr (diagnostic validation) @almallahmo @premsoman123 @DekempRob @BeanlandsRob @cmadamanchi & others not on SoMe