Jake Saba

MD/PhD student in Rachel Green's Lab
@HopkinsMedicine @GreenLabJHMI @HopkinsMDPhD @BCMB_JHMI

[Green Lab @GreenLabJHMI]

Excited to see our LARP1 manuscript published at The EMBO Journal. We show that LARP1 directly binds non-translating ribosomes and TOP mRNAs. An excellent collaboration with the @jingdongcheng lab!

https://t.co/VvDLODTn3n

[Green Lab @GreenLabJHMI]

We’ve captured the splitting image of Slh1: our work on an enzyme that splits collided ribosomes in E. coli is out on bioRxiv! Huge thanks to the @BeckmannLab, Burroughs, and Aravind for a great collaboration.

https://t.co/8B7GHWKTu0

[Green Lab @GreenLabJHMI]

Check out our new preprint in collaboration with @jingdongcheng lab about how LARP1 senses the abundance of non-translating ribosomes to help cells decide whether or not to make ribosomal proteins!

https://t.co/j5gJVMcXfk

[McManus Lab @CMU @McManusRNALab]

Sharing our new manuscript on bioRxiv.

[Green Lab @GreenLabJHMI]

Check out our new manuscript demonstrating that conserved uORFs regulate HOX mRNA translation. A fun collaboration with Tom Dever’s lab at the NIH. Spicier than Frank’s red HOX sauce 😉

https://t.co/4GsD1Nx91B

[Green Lab @GreenLabJHMI]

We tried to come up with a pun for this tweet, but it was a no-go 😉 check out our paper from @anthonyveltri out now on BioRxiv!
https://t.co/CZYWRNjGRs

[Green Lab @GreenLabJHMI]

Hot off the press!! 🔥🔥 The endonuclease SmrB is recruited to collided ribosomes to promote ribosome rescue in E. coli. Our latest work with @BeckmannLab, Max Burroughs, and L. Aravind, read the full story 👇
#ribosome #cryoEM #translation
https://t.co/72PKAdiBtx

[Beckmann Lab @BeckmannLab]

Making the cut ✂️
Ribosomal collisions matter also in bacteria! Collided disomes recruit SmrB, which comes to the rescue by cleaving the mRNA. Happy collaboration with the amazing @GreenLabJHMI and Allen Buskirk!
Preprint is out on @biorxivpreprint now! https://t.co/mOfA00gmbA

[Green Lab @GreenLabJHMI]

Hot off the press: new review on translation in stem cells by grad student @JakeSaba93 in collaboration with @KifLiakathAli and @FionaWattMRC. Check it out!

https://t.co/lzQDVffZOt